Zobrazeno 1 - 10
of 121
pro vyhledávání: '"Jianying, Xi"'
Autor:
Sushan Luo, Qilong Jiang, Wenshuang Zeng, Qinzhou Wang, Zhangyu Zou, Yanyan Yu, Daojun Hong, Quantao Zeng, Song Tan, Zhouao Zhang, Yong Zhang, Xiuming Guo, Jing Chen, Zhongyan Zhao, Shixiong Huang, Jianquan Shi, Ying Chen, Lei Du, Chong Yan, Jianying Xi, Jie Song, Chongbo Zhao, the Chinese Myasthenia Gravis Collaborating Group (CMGCG)
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 11, Iss 8, Pp 2212-2221 (2024)
Abstract Objective Efgartigimod, a neonatal Fc receptor antagonist, facilitates antibody degradation including pathogenic IgGs. The ADAPT study demonstrated the tolerability and efficacy of efgartigimod in the treatment of generalized myasthenia grav
Externí odkaz:
https://doaj.org/article/4ed052dcd6e640d5909d6e1483e6906d
Autor:
Jiaojiao Ma, Dan Chen, Fangfang Yi, Jie Song, Sushan Luo, Huahua Zhong, Jianying Xi, Zongtai Wu, Zunbo Li, Chongbo Zhao
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
IntroductionPatients with myasthenia gravis (MG) display strong treatment heterogeneity. Recent studies have indicated that low-dose steroids or immunosuppressants are effective. However, factors affecting the add-on of non-corticosteroid immunosuppr
Externí odkaz:
https://doaj.org/article/67e20c93e8504bcd97aa1718855d700e
Autor:
Huahua Zhong, Li Zeng, Xuefan Yu, Qing Ke, Jihong Dong, Yan Chen, Lijun Luo, Xueli Chang, Junhong Guo, Yiqi Wang, Hui Xiong, Rongrong Liu, Changxia Liu, Jibao Wu, Jie Lin, Jianying Xi, Wenhua Zhu, Song Tan, Fuchen Liu, Jiahong Lu, Chongbo Zhao, Sushan Luo
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 19, Iss 1, Pp 1-9 (2024)
Abstract Background As the most common subtype of adult muscular dystrophy worldwide, large cohort reports on myotonic dystrophy type I (DM1) in China are still lacking. This study aims to analyze the genetic and clinical characteristics of Chinese H
Externí odkaz:
https://doaj.org/article/43cef6e073334a009d68304f552df021
Autor:
Kexin Jiao, Jialong Zhang, Ningning Wang, Xingyu Gu, Xuechun Chang, Xingyu Xia, Bochen Zhu, Mingshi Gao, Nachuan Cheng, Chongbo Zhao, Jianying Xi, Wenhua Zhu
Publikováno v:
Stem Cell Research, Vol 81, Iss , Pp 103562- (2024)
GlcNAc2-epimerase myopathy is a rare autosomal recessive myopathy characterized by distal involvement in the lower extremities. Our study reprogrammed human-induced pluripotent stem cells from peripheral blood mononuclear cells of a patient with GNE
Externí odkaz:
https://doaj.org/article/72e21426c0fa43a5aca7565c4cfc1090
Autor:
Jie Song, Xiao Huan, Yuanyi Chen, Yeting Luo, Huahua Zhong, Yuan Wang, Lei Yang, Caihua Xi, Yu Yang, Jianying Xi, Jianming Zheng, Zongtai Wu, Chongbo Zhao, Sushan Luo
Publikováno v:
Therapeutic Advances in Neurological Disorders, Vol 17 (2024)
Eculizumab has improved recovery from ventilatory support in myasthenic crisis (MC) cases. However, the safety and efficacy profiles from prospective studies are still lacking. This study aimed to explore eculizumab’s safety and efficacy in a prosp
Externí odkaz:
https://doaj.org/article/3b2104cb0774475ebaf6d823628db8aa
Autor:
Jie Song, Haiyan Wang, Xiao Huan, Qilong Jiang, Zongtai Wu, Chong Yan, Jianying Xi, Chongbo Zhao, Huiyu Feng, Sushan Luo
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionEfgartigimod is effective and well-tolerated in patients with anti-acetylcholine receptor (AChR) antibody-positive generalized myasthenia gravis (MG). However, the therapeutic potential and the safety profile of efgartigimod in myasthenic
Externí odkaz:
https://doaj.org/article/32bd87e8d6494ba7a6f7117366d52b66
Autor:
Pan Wang, Bo Zhang, Jian Yin, Jianying Xi, Ying Tan, Feng Gao, Fan Zeng, Ting Chang, Hao Zhou, Hui Liang, Zhongyan Zhao, Huan Yang, Chongbo Zhao, Shixiong Huang
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
BackgroundDespite the efficacy of efgartigimod demonstrated in ADAPT phase 3 trial, data specifically derived from Chinese participants are not available. Therefore, we aimed to evaluate the efficacy and safety of efgartigimod in Chinese patients wit
Externí odkaz:
https://doaj.org/article/1c054960f55248aeaeb37c065cfb0adb
Autor:
Huahua Zhong, Xiao Huan, Rui Zhao, Manqiqige Su, Chong Yan, Jie Song, Jianying Xi, Chongbo Zhao, Feifei Luo, Sushan Luo
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-14 (2023)
Abstract Background Myasthenia gravis (MG) is the most prevalent autoimmune disorder affecting the neuromuscular junction. A rapid deterioration in respiratory muscle can lead to a myasthenic crisis (MC), which represents a life-threatening condition
Externí odkaz:
https://doaj.org/article/a4239e1daecf4466ae4bb09be2645a32
Autor:
Yuan Wang, Xiao Huan, Xinfang Zhu, Jie Song, Chong Yan, Lei Yang, Caihua Xi, Yafang Xu, Jianying Xi, Chongbo Zhao, Rong Xia, Sushan Luo
Publikováno v:
Therapeutic Advances in Neurological Disorders, Vol 17 (2024)
Background: Myasthenic crisis (MC) is a life-threatening condition for myasthenia gravis (MG). Therapeutic plasma exchange (TPE) and intravenous immunoglobulin (IVIg) efficaciously treat patients with MC. However, not every MC responds well to rescue
Externí odkaz:
https://doaj.org/article/31d2211feb514f87ba20413faf12a27f
Autor:
Yongsheng Zheng, Jianian Hu, Chong Sun, Kai Qiao, Yanyin Zhao, Bingyou Liu, Jian Sun, Jianying Xi, Sushan Luo, Jiahong Lu, Chongbo Zhao, Jie Lin
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
BackgroundRefractory chronic inflammatory demyelinating polyneuropathy (CIDP) is a challenging subset of CIDP. It does not respond well to immune therapy and causes substantial disability. A comprehensive understanding of its clinical profile, electr
Externí odkaz:
https://doaj.org/article/90ba3bb707d444bfa83a668b18a5a16f