Zobrazeno 1 - 10
of 808
pro vyhledávání: '"Jianying, Hu"'
Autor:
Hongxin Xiang, Li Zeng, Linlin Hou, Kenli Li, Zhimin Fu, Yunguang Qiu, Ruth Nussinov, Jianying Hu, Michal Rosen-Zvi, Xiangxiang Zeng, Feixiong Cheng
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Accurate molecular representation of compounds is a fundamental challenge for prediction of drug targets and molecular properties. In this study, we present a molecular video-based foundation model, named VideoMol, pretrained on 120 million
Externí odkaz:
https://doaj.org/article/d86f383c80f347838207afa1e693fe5c
Publikováno v:
Environment International, Vol 191, Iss , Pp 108996- (2024)
Prenatal exposure to organophosphorus flame retardants (OPFRs) has been linked with adverse effects on reproductive health, and new OPFRs are continually emerging. In this study, emerging OPFRs, such as bis(2-ethylhexyl) phenyl phosphate (BEHPP), tri
Externí odkaz:
https://doaj.org/article/e67e553f672d4930b43215d3e530f9d6
Autor:
Haoran Xu, Wenxiao Zhang, Yu’ang Ren, Yuanzheng Zhang, Jin Li, Shuxiu Zheng, Rong Dai, Jianying Hu, Hefa Cheng, Guofeng Shen, Huizhong Shen, Jianmin Ma, Shu Tao
Publikováno v:
Environment International, Vol 190, Iss , Pp 108936- (2024)
Electricity production is a significant source of air pollution. Various factors, including electricity demand, generation efficiency, energy mix, and end-of-pipe control measures, are responsible for the emission changes during electricity generatio
Externí odkaz:
https://doaj.org/article/dfc5f5bde39f4d709d7946c67253454d
Endocrine-Disruptive Effects of Adenylate Cyclase Activator Forskolin: In Vitro and In Vivo Evidence
Publikováno v:
Toxics, Vol 12, Iss 10, p 701 (2024)
Forskolin (FSK) is a potent adenylate cyclase activator and may display endocrine-disruptive effects via the disruption of steroidogenesis. Here, we tested this hypothesis by use of the in vitro H295R steroidogenesis assay and the in vivo long-term m
Externí odkaz:
https://doaj.org/article/a4d0dd1379df42cf8c97c8a123df9ddb
Autor:
Zhaonan Sun, Jennifer Ware, Sanjoy Dey, Elif Eyigoz, Swati Sathe, Cristina Sampaio, Jianying Hu
Publikováno v:
Frontiers in Aging Neuroscience, Vol 16 (2024)
BackgroundUnderstanding the sensitivity and utility of clinical assessments across different HD stages is important for study/trial endpoint selection and clinical assessment development. The Integrated HD Progression Model (IHDPM) characterizes the
Externí odkaz:
https://doaj.org/article/a0cb3a9763a545fead3af24cc2292ddc
Autor:
Chenhao Lin, Zhonghan Sun, Zhendong Mei, Hailuan Zeng, Manying Zhao, Jianying Hu, Mingfeng Xia, Tao Huang, Chaolong Wang, Xin Gao, Yan Zheng
Publikováno v:
BMC Medicine, Vol 20, Iss 1, Pp 1-11 (2022)
Abstract Background Circulating levels of amino acids were associated with blood pressure (BP) in observational studies. However, the causation of such associations has been hypothesized but is difficult to prove in human studies. Here, we aimed to u
Externí odkaz:
https://doaj.org/article/d8c70d35ceea461aba1a04a8e9597b62
Autor:
Jianying Hu, Manying Zhao, Chenhao Lin, Zhonghan Sun, Guo-Chong Chen, Zhendong Mei, Yan Zheng
Publikováno v:
Nutrition & Metabolism, Vol 19, Iss 1, Pp 1-11 (2022)
Abstract Background The associations between visceral adipose tissue (VAT) and bone mineral density (BMD) or fracture have been controversial and the causality of the associations remains to be assessed. This study aimed to explore the associations o
Externí odkaz:
https://doaj.org/article/c694c207af074447b8804f83131154cc
Publikováno v:
BMC Pregnancy and Childbirth, Vol 22, Iss 1, Pp 1-8 (2022)
Abstract Background Decreasing the anaesthesia preparation time for primiparas experiencing painful uterine contractions is clinically relevant. This prospective intervention study investigated the effect of various educational methods conducted at d
Externí odkaz:
https://doaj.org/article/0cc3a69f3ca74f99912dbb9e032d1321
Autor:
Zhonghan Sun, Xiong‐Fei Pan, Xiao Li, Limiao Jiang, Ping Hu, Yi Wang, Yi Ye, Ping Wu, Bin Zhao, Jianguo Xu, Mengmeng Kong, Yanni Pu, Manying Zhao, Jianying Hu, Jinfeng Wang, Guo‐Chong Chen, Changzheng Yuan, Yongfu Yu, Xiang Gao, Fangqing Zhao, An Pan, Yan Zheng
Publikováno v:
Advanced Science, Vol 10, Iss 10, Pp n/a-n/a (2023)
Abstract Though gut microbiome disturbance may be involved in the etiology of gestational diabetes mellitus (GDM), data on the gut microbiome's dynamic change during pregnancy and associations with gestational glucose metabolism are still inadequate.
Externí odkaz:
https://doaj.org/article/151f7f35147b41a5a8ef43ab690e54f4
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 255, Iss , Pp 114719- (2023)
The combination of glyphosate (Gly) and hard water (Hwt) is a suspected risk factor for chronic interstitial nephritis in agricultural communities (CINAC). Accumulated mitochondrial damage and proximal tubular epithelial (PTE) cell senescence have be
Externí odkaz:
https://doaj.org/article/67935a0c6d8049988523e723ff4d164e