Zobrazeno 1 - 10
of 120
pro vyhledávání: '"Jianye Zang"'
Autor:
Xinhao Hou, Mingjing Xu, Chengming Zhu, Jianing Gao, Meili Li, Xiangyang Chen, Cheng Sun, Björn Nashan, Jianye Zang, Ying Zhou, Shouhong Guang, Xuezhu Feng
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Chromodomains mainly function as histone methyl-lysine readers to regulate gene expression. Here the authors delineate a functional map of chromodomain proteins and identify an H3K9me1/2 writer, MET-2, and reader, CEC-5, that are required for the nor
Externí odkaz:
https://doaj.org/article/8405873977c64abc95c3ceb3b596b2e1
Autor:
Tian Tian, Lili Chen, Zhen Dou, Zhisen Yang, Xinjiao Gao, Xiao Yuan, Chengliang Wang, Ran Liu, Zuojun Shen, Ping Gui, Maikun Teng, Xianlei Meng, Donald L. Hill, Lin Li, Xuan Zhang, Xing Liu, Linfeng Sun, Jianye Zang, Xuebiao Yao
Publikováno v:
Cell Discovery, Vol 8, Iss 1, Pp 1-15 (2022)
Abstract In mitosis, accurate chromosome segregation depends on kinetochores that connect centromeric chromatin to spindle microtubules. The centromeres of budding yeast, which are relatively simple, are connected to individual microtubules via a kin
Externí odkaz:
https://doaj.org/article/0bf28f73ca5b42b4815a2209652cc3a5
Autor:
Nan Jia, Guo Li, Xing Wang, Qing Cao, Wanbiao Chen, Chengliang Wang, Ling Chen, Xiaoling Ma, Xuan Zhang, Yue Tao, Jianye Zang, Xi Mo, Jinfeng Hu
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-14 (2022)
The Staphylococcal superantigen like protein 10 induces necroptosis in human cells through binding to TNFR1 by both the N- and C-terminal domains and activating RIPK1-RIPK3-MLKL and RIPK3-CaMKII-mitochondrial permeability transition pore pathways.
Externí odkaz:
https://doaj.org/article/cbe5f666ad724953be2c2ec7b9654009
Autor:
Hanxiao Zu, Chang Li, Chenrui Dai, Yi Pan, Chen Ding, Huiying Sun, Xuan Zhang, Xuebiao Yao, Jianye Zang, Xi Mo
Publikováno v:
Cell Discovery, Vol 8, Iss 1, Pp 1-5 (2022)
Externí odkaz:
https://doaj.org/article/8763545e1c1c47ddaf04482666c82df3
Autor:
Liping Li, Hui Lu, Xuan Zhang, Malcolm Whiteway, Hao Wu, Shanlun Tan, Jianye Zang, Shujuan Tian, Cheng Zhen, Xianlei Meng, Wanqian Li, Dazhi Zhang, Min Zhang, Yuanying Jiang
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 4 (2022)
ABSTRACT Baicalein (BE) is a promising antifungal small-molecule compound with an extended antifungal spectrum, good synergy with fluconazole, and low toxicity, but its target protein and antifungal mechanism remain elusive. In this study, we found t
Externí odkaz:
https://doaj.org/article/b3aeee0ef50b4f949e9b66fa08dcf109
Autor:
Tiantian Fang, Wanbiao Chen, Yaping Sheng, Siming Yuan, Qiaowei Tang, Gongyu Li, Guangming Huang, Jihu Su, Xuan Zhang, Jianye Zang, Yangzhong Liu
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-8 (2019)
Tetrathiomolybdate (TM) and Cu-ATPases, e.g. Wilson (WLN) protein, affect the efficacy of common anticancer drug cisplatin. Here, the authors show that TM generates a protein dimer with a WLN domain by expelling copper and provide insight into the sy
Externí odkaz:
https://doaj.org/article/eb788873ae41467b98ebc2094c4d5779
Autor:
Jianlin Lu, Yuanyuan Huang, Li Zhan, Ming Wang, Leilei Xu, McKay Mullen, Jianye Zang, Guowei Fang, Zhen Dou, Xing Liu, Wei Liu, Minerva Garcia-Barrio, Xuebiao Yao
Publikováno v:
iScience, Vol 24, Iss 4, Pp 102363- (2021)
Summary: AMP-activated protein kinase (AMPK) senses energy status and impacts energy-consuming events by initiating metabolism regulatory signals in cells. Accumulating evidences suggest a role of AMPK in mitosis regulation, but the mechanism of mito
Externí odkaz:
https://doaj.org/article/cd2495f193bf4a3683ac22d7a4800b26
Publikováno v:
Nanomaterials, Vol 8, Iss 6, p 446 (2018)
Slow and controlled release systems for drugs have attracted increasing interest recently. A highly efficient metal-organic gel (MOGs) drug delivery carrier, i.e., MIL-100(Al) gel, has been fabricated by a facile, low cost, and environmentally friend
Externí odkaz:
https://doaj.org/article/8a63d41772d7463f82cdac6b878a6c2e
Autor:
Jianbin Ruan, Hui Ouyang, Maria F Amaya, Mani Ravichandran, Peter Loppnau, Jinrong Min, Jianye Zang
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e35376 (2012)
HP1 proteins are highly conserved heterochromatin proteins, which have been identified to be structural adapters assembling a variety of macromolecular complexes involved in regulation of gene expression, chromatin remodeling and heterochromatin form
Externí odkaz:
https://doaj.org/article/ce8106af909141beb3caa5f1b34f7090
Autor:
Jing Li, Zhihong Li, Jianbin Ruan, Chao Xu, Yufeng Tong, Patricia W Pan, Wolfram Tempel, Lissete Crombet, Jinrong Min, Jianye Zang
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e25104 (2011)
M-phase phosphoprotein 8 (MPP8) was initially identified to be a component of the RanBPM-containing large protein complex, and has recently been shown to bind to methylated H3K9 both in vivo and in vitro. MPP8 binding to methylated H3K9 is suggested
Externí odkaz:
https://doaj.org/article/e45b3e5623ce4eab9a939f9ddbfff167