Zobrazeno 1 - 10
of 91
pro vyhledávání: '"Jianye Cai"'
Autor:
Rong Li, Xijing Yan, Cuicui Xiao, Tingting Wang, Xuejiao Li, Zhongying Hu, Jinliang Liang, Jiebin Zhang, Jianye Cai, Xin Sui, Qiuli Liu, Manli Wu, Jiaqi Xiao, Haitian Chen, Yasong Liu, Chenhao Jiang, Guo Lv, Guihua Chen, Yingcai Zhang, Jia Yao, Jun Zheng, Yang Yang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract Older livers are more prone to hepatic ischaemia/reperfusion injury (HIRI), which severely limits their utilization in liver transplantation. The potential mechanism remains unclear. Here, we demonstrate older livers exhibit increased ferrop
Externí odkaz:
https://doaj.org/article/82572909d6d141f9893068bc97990bd4
Autor:
Haitian Chen, Wen Yin, Kang Yao, Jinliang Liang, Jianye Cai, Xin Sui, Xuegang Zhao, Jiebin Zhang, Jiaqi Xiao, Rong Li, Qiuli Liu, Jia Yao, Guohua You, Yasong Liu, Chenhao Jiang, Xiaotong Qiu, Tingting Wang, Qiang You, Yingcai Zhang, Mo Yang, Jun Zheng, Zong Dai, Yang Yang
Publikováno v:
Advanced Science, Vol 11, Iss 32, Pp n/a-n/a (2024)
Abstract Hepatic ischemia‐reperfusion injury (HIRI) is a prevalent issue during liver resection and transplantation, with currently no cure or FDA‐approved therapy. A promising drug, Cyclosporin A (CsA), ameliorates HIRI by maintaining mitochondr
Externí odkaz:
https://doaj.org/article/fcfcbcb4104445b799ce1c3f46e97ee0
Autor:
Chenhao Jiang, Huaxin Chen, Yinqian Kang, Xinyi He, Jianyang Huang, Tongyu Lu, Xin Sui, Haitian Chen, Jiaqi Xiao, Jiebin Zhang, Hanwen Zhang, Jun Zheng, Yang Yang, Jia Yao, Jianye Cai, Yingcai Zhang
Publikováno v:
Cell Death Discovery, Vol 9, Iss 1, Pp 1-10 (2023)
Abstract The therapeutic potential of umbilical cord-mesenchymal stem cell (UC-MSC) transplantation in liver fibrosis has been highlighted. However, the fate of transplanted MSCs in the fibrotic microenvironment remains unclear. In this study, we aim
Externí odkaz:
https://doaj.org/article/7754c39d7fae4450aa36183a1f3f34cd
Autor:
Jun Zheng, Xijing Yan, Tongyu Lu, Wen Song, Yang Li, Jinliang Liang, Jiebin Zhang, Jianye Cai, Xin Sui, Jiaqi Xiao, Haitian Chen, Guihua Chen, Qi Zhang, Yubin Liu, Yang Yang, Kanghong Zheng, Zihao Pan
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-22 (2023)
Abstract Background The Warburg effect is well-established to be essential for tumor progression and accounts for the poor clinical outcomes of hepatocellular carcinoma (HCC) patients. An increasing body of literature suggests that circular RNAs (cir
Externí odkaz:
https://doaj.org/article/2615bf663e0f4801994084063e0fa581
Autor:
Xiaotong Qiu, Jianye Cai, Haitian Chen, Jia Yao, Cuicui Xiao, Rong Li, Jiaqi Xiao, Jiebin Zhang, Xin Sui, Tongyu Lu, Jun Zheng, Yingcai Zhang, Yang Yang
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BackgroundThe purpose of this study is to evaluate the effects of chemotherapy and radiotherapy on the prognosis of unresectable HCC patients with portal and/or hepatic vein invasion.MethodsA retrospective analysis of unresectable HCC patients with p
Externí odkaz:
https://doaj.org/article/3985aa122cec4a5b83fb6e3b71e8f98b
Autor:
Senyu Yao, Xiaoyue Wei, Wenrui Deng, Boyan Wang, Jianye Cai, Yinong Huang, Xiaofan Lai, Yuan Qiu, Yi Wang, Yuanjun Guan, Jiancheng Wang
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
The regulatory mechanisms contributing to male reproductive ageing are unknown. Here, the authors show that Nestin-dependent mito-ER contacts (MERCs) regulate stem Leydig cell (SLC) senescence and provide insights into SLCs-targeting therapies.
Externí odkaz:
https://doaj.org/article/2845439343764e1fba6f73eab2348679
Autor:
Haijin Lv, Xiaofeng Yuan, Jiebin Zhang, Tongyu Lu, Jia Yao, Jun Zheng, Jianye Cai, Jiaqi Xiao, Haitian Chen, Shujuan Xie, Ying Ruan, Yuling An, Xin Sui, Huimin Yi
Publikováno v:
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-16 (2021)
Abstract Objectives Acute lung injury (ALI) remains a common cause of morbidity and mortality worldwide, and to date, there is no effective treatment for ALI. Previous studies have revealed that topical administration of mesenchymal stem cells (MSCs)
Externí odkaz:
https://doaj.org/article/e24d02dbf0dd41d79daed464995f09fa
Autor:
Yingcai Zhang, Jiebin Zhang, Huimin Yi, Jun Zheng, Jianye Cai, Wenjie Chen, Tongyu Lu, Liang Chen, Cong Du, Jianrong Liu, Jia Yao, Hui Zhao, Guoying Wang, Binsheng Fu, Tong Zhang, Jian Zhang, Genshu Wang, Hua Li, Andy Peng Xiang, Guihua Chen, Shuhong Yi, Qi Zhang, Yang Yang
Publikováno v:
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-15 (2021)
Abstract Background ABO-incompatible liver transplantation (ABO-i LT) has become a rescue therapeutic option for patients with severe hepatic failure. Although the use of rituximab greatly reduces the morbidity of antibody-mediated rejection (AMR), s
Externí odkaz:
https://doaj.org/article/180a8bea56334d9fad8a52fc2b6a49a6
Autor:
Boyan Wang, Yi Wang, Hainan Chen, Senyu Yao, Xiaofan Lai, Yuan Qiu, Jianye Cai, Yinong Huang, Xiaoyue Wei, Yuanjun Guan, Tao Wang, Jiancheng Wang, Andy Peng Xiang
Publikováno v:
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-17 (2021)
Abstract Background Cancer cachexia is a wasting syndrome that is quite common in terminal-stage cancer patients. Cancer-related anemia is one of the main features of cancer cachexia and mostly results in a poor prognosis. The disadvantages of the cu
Externí odkaz:
https://doaj.org/article/be482fd51d0c493ba40c226677da0c70
Autor:
Jiaqi Sun, Yinong Huang, Jin Gong, Jiancheng Wang, Yubao Fan, Jianye Cai, Yi Wang, Yuan Qiu, Yili Wei, Chuanfeng Xiong, Jierui Chen, Bin Wang, Yuanchen Ma, Lihua Huang, Xiaoyong Chen, Shuwei Zheng, Weijun Huang, Qiong Ke, Tao Wang, Xiaoping Li, Wei Zhang, Andy Peng Xiang, Weiqiang Li
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-20 (2020)
Pericytes play an essential role in blood brain barrier (BBB) integrity. Here, the authors generate pericyte-like cells (PCs) from human pluripotent stem cells (hPSCs) which display functional properties and also promote BBB recovery in a mouse model
Externí odkaz:
https://doaj.org/article/c8098a945ee5461faca4a71cc390c57e