Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Jianya, Peng"'
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Parasitic helminth infections remain a significant global health issue and are responsible for devastating morbidity and economic hardships. During infection, helminths migrate through different host organs, which results in substantial tissue damage
Externí odkaz:
https://doaj.org/article/e3098569f9e648dd80f6132a41db61d8
Autor:
Constance McElrath, Vanessa Espinosa, Jian-Da Lin, Jianya Peng, Raghavendra Sridhar, Orchi Dutta, Hsiang-Chi Tseng, Sergey V. Smirnov, Heidi Risman, Marvin J. Sandoval, Viralkumar Davra, Yun-Juan Chang, Brian P. Pollack, Raymond B. Birge, Mark Galan, Amariliz Rivera, Joan E. Durbin, Sergei V. Kotenko
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Despite being prevalent yet well studied, ulcerative colitis still has poorly characterized pathophysiology. Here the authors use mouse colitis models to find that type I and III interferon (IFN) both contribute to ameliorating the disease, with IFN
Externí odkaz:
https://doaj.org/article/71db4af0b0d54c2a94af312d1646e924
Autor:
Jianya Peng, Chandler B. Sy, John J. Ponessa, Alexander D. Lemenze, Christina M. Hernandez, Juan M. Inclan-Rico, Arman Sawhney, Hannah G. Federman, Krupa Chavan, Vanessa Espinosa, Sergei V. Kotenko, Amariliz Rivera, Mark C. Siracusa
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(37)
Neuroimmune interactions are crucial for regulating immunity and inflammation. Recent studies have revealed that the central nervous system (CNS) senses peripheral inflammation and responds by releasing molecules that limit immune cell activation, th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74605ebc15be14b24faea65c1d27b923
https://pubmed.ncbi.nlm.nih.gov/36070344
https://pubmed.ncbi.nlm.nih.gov/36070344
Autor:
Marvin J. Sandoval, Jianya Peng, Heidi P. Risman, Viralkumar Davra, Amariliz Rivera, Raghavendra Rao Sridhar, Yun-Juan Chang, Brian Pollack, Sergei V. Kotenko, Orchi Dutta, Raymond B. Birge, Joan E. Durbin, Constance McElrath, Mark Galan, Sergey V. Smirnov, Vanessa Espinosa, Hsiang-Chi Tseng, Jian-Da Lin
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
The etiology of ulcerative colitis is poorly understood and is likely to involve perturbation of the complex interactions between the mucosal immune system and the commensal bacteria of the gut, with cytokines acting as important cross-regulators. He
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6449e01e27c062a40e8a417a48467d7
https://doaj.org/article/71db4af0b0d54c2a94af312d1646e924
https://doaj.org/article/71db4af0b0d54c2a94af312d1646e924
Autor:
Jian-Da Lin, Ningguo Feng, Adrish Sen, Murugabaskar Balan, Hsiang-Chi Tseng, Constance McElrath, Sergey V Smirnov, Jianya Peng, Linda L Yasukawa, Russell K Durbin, Joan E Durbin, Harry B Greenberg, Sergei V Kotenko
Publikováno v:
PLoS Pathogens, Vol 12, Iss 6, p e1005726 (2016)
[This corrects the article DOI: 10.1371/journal.ppat.1005600.].
Externí odkaz:
https://doaj.org/article/51d21d2714f6400aae3e07ffb6f44eec
Autor:
Jian-Da Lin, Ningguo Feng, Adrish Sen, Murugabaskar Balan, Hsiang-Chi Tseng, Constance McElrath, Sergey V Smirnov, Jianya Peng, Linda L Yasukawa, Russell K Durbin, Joan E Durbin, Harry B Greenberg, Sergei V Kotenko
Publikováno v:
PLoS Pathogens, Vol 12, Iss 4, p e1005600 (2016)
Type I (IFN-α/β) and type III (IFN-λ) interferons (IFNs) exert shared antiviral activities through distinct receptors. However, their relative importance for antiviral protection of different organ systems against specific viruses remains to be fu
Externí odkaz:
https://doaj.org/article/a051314a708e4baf9c40ca92069aa2b4
Autor:
Jianya Peng, Mark C. Siracusa
Publikováno v:
Semin Immunol
It has been appreciated that basophilia is a common feature of helminth infections for approximately 50 years. The ability of basophils to secrete IL-4 and other type 2 cytokines has supported the prevailing notion that basophils contribute to antihe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a34b24125fdb9ef0deb5f4e2d162f121
https://pubmed.ncbi.nlm.nih.gov/34815162
https://pubmed.ncbi.nlm.nih.gov/34815162
Autor:
Hunter MacDonald, Jianya Peng, Arnold Johnson, Nancy Gertzberg, Janey James, Paul Neumann, Vincenzo Russo, Carlos Feleder
Publikováno v:
Journal of Neuroimmunology. 286:16-24
We investigated the role of intracerebroventricular (ICV) injection of rimonabant (500 ng), a CB1 antagonist, on lipopolysaccharide ((LPS) 5mg/kg)-induced pulmonary inflammation in rats in an isolated perfused lung model. There were decreases in pulm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7beea20a55bca56c6c85f3c8a21cc016
https://doi.org/10.1016/j.jneuroim.2015.07.001
https://doi.org/10.1016/j.jneuroim.2015.07.001
Publikováno v:
Journal of neuroimmunology. 285
This study tested the hypothesis that lipopolysaccharide (LPS) lowers arterial pressure through two different mechanisms depending on the dose. Previously, we found that a low hypotensive dose of LPS (1 mg/kg) lowers arterial pressure by activating v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8dc88b691526020cf721e82939c51ed
https://pubmed.ncbi.nlm.nih.gov/26198924
https://pubmed.ncbi.nlm.nih.gov/26198924
Publikováno v:
The FASEB Journal. 28
Sepsis is a systemic inflammatory response caused by infection which can lead to shock and lung injury. Previous studies indicate that septic shock is mediated by brain endocannabinoid 1 (CB1) receptors. Hence, this study tested the hypothesis that t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::471660cc158719303398fe88145618ae
https://doi.org/10.1096/fasebj.28.1_supplement.1157.4
https://doi.org/10.1096/fasebj.28.1_supplement.1157.4