Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Jianya, Huan"'
Autor:
Peter Kurre, Charles T. Roberts, Natalya A. Goloviznina, Amy M. Skinner, Matthew J. Shurtleff, Noah I. Hornick, Jianya Huan
PDF file - 156K, AML exosomes can alter gene expression and protein secretion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ad7ecbe2d2e69d593d40f8b01735c63
https://doi.org/10.1158/0008-5472.22399322
https://doi.org/10.1158/0008-5472.22399322
Autor:
Peter Kurre, Charles T. Roberts, Natalya A. Goloviznina, Amy M. Skinner, Matthew J. Shurtleff, Noah I. Hornick, Jianya Huan
PDF file - 2.9MB, The detection of IGF-1R in HL-60 cell and vesicle lysates by Western blot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::019ce720ae97786fc96a32f78828ed05
https://doi.org/10.1158/0008-5472.22399328
https://doi.org/10.1158/0008-5472.22399328
Autor:
Peter Kurre, Charles T. Roberts, Natalya A. Goloviznina, Amy M. Skinner, Matthew J. Shurtleff, Noah I. Hornick, Jianya Huan
PDF file - 143K, All primers were used in semi-quantitative PCR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fd160e44a029592b3d8f55b7406b9d4
https://doi.org/10.1158/0008-5472.22399319
https://doi.org/10.1158/0008-5472.22399319
Autor:
Peter Kurre, Charles T. Roberts, Natalya A. Goloviznina, Amy M. Skinner, Matthew J. Shurtleff, Noah I. Hornick, Jianya Huan
PDF file - 456K, Co-culture of AML cells with stromal cell can alter gene expression and protein secretion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d56e7b5fdd7d0f9de9c65f824992bed
https://doi.org/10.1158/0008-5472.22399325
https://doi.org/10.1158/0008-5472.22399325
Autor:
Richard L. Klemke, Donna E. Hansel, Huawei Wang, Gerry R. Boss, Darren E. Casteel, Divya Sahu, Jianya Huan, Debashis Sahoo
Publikováno v:
The American Journal of Pathology. 191:2203-2218
Bladder cancer invasion depends on mammalian target of rapamycin complex 2 (mTORC2) activity, although the downstream mTORC2 effectors that mediate this effect have not been fully defined. One potential downstream effector is the arginine derivative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fe1a16fb0b7befdb5a09460910e4295
https://doi.org/10.1016/j.ajpath.2021.08.002
https://doi.org/10.1016/j.ajpath.2021.08.002
Publikováno v:
Cancers. 14(6)
The mammalian target of rapamycin (mTOR) pathway regulates important cellular functions. Aberrant activation of this pathway, either through upstream activation by growth factors, loss of inhibitory controls, or molecular alterations, can enhance can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7014bf8b9dc333ffdcf4dafdf59420b0
https://pubmed.ncbi.nlm.nih.gov/35326708
https://pubmed.ncbi.nlm.nih.gov/35326708
Autor:
Clare, Keddy, Tanaya, Neff, Jianya, Huan, Joshua P, Nickerson, Catherine Z, Beach, Yassmine, Akkari, Jianling, Ji, Stephen, Moore, Kellie J, Nazemi, Christopher L, Corless, Carol, Beadling, Randy, Woltjer, Yoon-Jae, Cho, Matthew D, Wood, Monika A, Davare
Publikováno v:
Cold Spring Harbor Molecular Case Studies
Chromosomal rearrangements of the NTRK genes generate kinase fusions that are targetable oncogenic drivers in diverse adult and pediatric malignancies. Despite robust clinical response to targeted NTRK inhibition, the emergence of therapeutic resista
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0e44ec266f980cbac6953532a44fe483
https://pubmed.ncbi.nlm.nih.gov/34429303
https://pubmed.ncbi.nlm.nih.gov/34429303
Autor:
Catherine Z. Beach, Kellie J. Nazemi, Stephen Moore, Joshua P. Nickerson, Carol Beadling, Matthew D. Wood, Yoon Jae Cho, Tanaya Neff, Randy Woltjer, Clare Keddy, Christopher L. Corless, Jianling Ji, Yassmine Akkari, Monika A. Davare, Jianya Huan
Publikováno v:
Molecular Case Studies. 7:a006109
Chromosomal rearrangements of the NTRK genes generate kinase fusions that are targetable oncogenic drivers in diverse adult and pediatric malignancies. Despite robust clinical response to targeted NTRK inhibition, the emergence of therapeutic resista
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ff82810d56dba19387310ce78f997da
https://doi.org/10.1101/mcs.a006109
https://doi.org/10.1101/mcs.a006109
Autor:
Phillip A. Wilmarth, Jianya Huan, Natalya A. Goloviznina, Noah I. Hornick, A N Kamimae Lanning, Larry L. David, Bill H. Chang, Peter Kurre, T Mori, Charles T. Roberts, John R. Chevillet, Anupama Narla, Marc M. Loriaux
Publikováno v:
Leukemia. 29:2285-2295
We recently demonstrated that acute myeloid leukemia (AML) cell lines and patient-derived blasts release exosomes that carry RNA and protein; following an in vitro transfer, AML exosomes produce proangiogenic changes in bystander cells. We reasoned t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfe5d873176c7c9a34c0a5f2a7488542
https://doi.org/10.1038/leu.2015.163
https://doi.org/10.1038/leu.2015.163
Autor:
Charles T. Roberts, Jianya Huan, Amy M. Skinner, Natalya A. Goloviznina, Noah I. Hornick, Peter Kurre, Matthew J Shurtleff
Publikováno v:
Cancer Research. 73:918-929
Extrinsic signaling cues in the microenvironment of acute myelogenous leukemia (AML) contribute to disease progression and therapy resistance. Yet, it remains unknown how the bone marrow niche in which AML arises is subverted to support leukemic pers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd6bc44c5211566def48e1dd304244f6
https://doi.org/10.1158/0008-5472.can-12-2184
https://doi.org/10.1158/0008-5472.can-12-2184