Zobrazeno 1 - 10
of 572
pro vyhledávání: '"Jianxun Wang"'
Autor:
Yi Jia, Xiaosu Yuan, Luxin Feng, Qingling Xu, Xinyu Fang, Dandan Xiao, Qi Li, Yu Wang, Lin Ye, Peiyan Wang, Xiang Ao, Jianxun Wang
Publikováno v:
Cellular & Molecular Biology Letters, Vol 29, Iss 1, Pp 1-25 (2024)
Abstract Background Circular RNAs (circRNAs) are differentially expressed in various cardiovascular diseases, including myocardial infarction (MI) injury. However, their functional role in necroptosis-induced loss of cardiomyocytes remains unclear. W
Externí odkaz:
https://doaj.org/article/73dcaa0ae1cc4581a3bf675b6866d5cb
Autor:
Jingjing Zhu, Jing Zhang, Ping Wang, Xiuying Liu, Jingjing Liu, Yichao Feng, Mary Yue Jiang, Zhiqiao Feng, Xiaoqing Yao, Jianxun Wang
Publikováno v:
Journal of Traditional Chinese Medical Sciences, Vol 11, Iss 4, Pp 466-475 (2024)
Objective: To investigate the effects and mechanisms of Xuebijing injection (XBJ) on Chimeric antigen receptor-T (CAR-T) cell function and its therapeutic potential against CAR-T therapy-associated cytokine storms (CRS). Methods: Anti-CD19 CAR-T cell
Externí odkaz:
https://doaj.org/article/b9c83cd6dbe04007b856294ef058069a
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract The response of cardiac fibroblast proliferation to detrimental stimuli is one of the main pathological factors causing heart remodeling. Reactive oxygen species (ROS) mediate the proliferation of cardiac fibroblasts. However, the exact mole
Externí odkaz:
https://doaj.org/article/4f4dba356da34735a758b69eb682582d
Autor:
Liqiong Liu, Wenxiang Zhu, Ning Liu, Shiting Gong, Qihong Ma, Huanhuan Zhou, Nan Zhong, Wei Dai, Lijun Zhao, Rui Sun, Jianxun Wang, Yuanyuan Shi, Zhi Guo
Publikováno v:
Heliyon, Vol 10, Iss 17, Pp e36955- (2024)
Chimeric antigen receptor T (CAR-T)-cell therapy targeting B-cell maturation antigen (BCMA) is currently one of the promising treatment methods for relapsed/refractory multiple myeloma (MM). Herein, this study is a case report on a 41-year-old male p
Externí odkaz:
https://doaj.org/article/fbd0e7d8e2414c7fb7d3bfccadbdd843
Publikováno v:
Annals of Medicine, Vol 56, Iss 1 (2024)
Apoptosis repressor with caspase recruitment domain (ARC) is a highly potent and multifunctional suppressor of various types of programmed cell death (PCD) (e.g. apoptosis, necroptosis, and pyroptosis) and plays a key role in determining cell fate. U
Externí odkaz:
https://doaj.org/article/f3177a71b0db4d959b3dbb83c04fb994
Autor:
Shuo Miao, Lanting Yang, Tao Xu, Zhantao Liu, Yixiao Zhang, Lin Ding, Wei Ding, Xiang Ao, Jianxun Wang
Publikováno v:
MedComm, Vol 5, Iss 6, Pp n/a-n/a (2024)
Abstract Iron overload is common in cardiovascular disease, it is also the factor that drives ferroptosis. Noncoding RNAs play an important role in heart disease; however, their regulatory role in iron overload‐mediated ferroptosis remains much unk
Externí odkaz:
https://doaj.org/article/8d307329b336417ba9f26c494929b23b
Publikováno v:
Cellular & Molecular Biology Letters, Vol 29, Iss 1, Pp 1-25 (2024)
Abstract Background Circular RNAs are enriched in cardiac tissue and play important roles in the pathogenesis of heart diseases. In this study, we aimed to investigate the regulatory mechanism of a conserved heart-enriched circRNA, circPan3, in cardi
Externí odkaz:
https://doaj.org/article/fe6e9f00a31349ca90d6af23cb541030
Autor:
Qianqian Xue, Yanyan Yang, Hong Li, Xiaoxin Li, Lu Zou, Tianxiang Li, Huibo Ma, Hongzhao Qi, Jianxun Wang, Tao Yu
Publikováno v:
Genes and Diseases, Vol 10, Iss 6, Pp 2479-2490 (2023)
Post-translational modifications (PTM) are covalent modifications of proteins or peptides caused by proteolytic cleavage or the attachment of moieties to one or more amino acids. PTMs play essential roles in biological function and regulation and hav
Externí odkaz:
https://doaj.org/article/7f728d180615482dab89480ae2e67605
Publikováno v:
Applied Sciences, Vol 14, Iss 16, p 7356 (2024)
Stage-built long-span bridges deform with temperature, affecting alignment to design needs. In this paper, a model for predicting temperature time series is proposed, which can predict temperatures in engineering practice and utilize the predicted re
Externí odkaz:
https://doaj.org/article/ce1e99fe5bb74bebba8d27ce7e3d3a5a
Autor:
Prabh R. Pannu, Chijioke Chukwudi, Jianxun Wang, Po‐Jen Yang, Farid Nasr Esfahani, Nima Saeidi
Publikováno v:
Obesity Science & Practice, Vol 9, Iss 3, Pp 274-284 (2023)
Abstract Objective Metabolic and morphological adaptations of the intestine have been suggested to play a role in the various therapeutic benefits of Roux‐en‐Y Gastric Bypass (RYGB) surgery. However, the precise underlying mechanisms remain uncle
Externí odkaz:
https://doaj.org/article/72cb2700b96548fbacd856ce568c605c