Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Jianxin Mai"'
Autor:
Jianxin Mai, Izabela Podgorski, Michael L. Cher, Dora Cavallo-Medved, Mansoureh Sameni, Kamiar Moin, Bonnie F. Sloane, Julie Dosescu, Shiqing Yan, Bruce E. Linebaugh
Publikováno v:
Biological Sciences Publications
Tumor-stromal interactions induce expression of matrix metalloproteinases and serine proteases and, as shown recently, the cysteine protease cathepsin B. We speculate that such interactions upregulate the transcription factor Ets1, resulting in incre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19bfdce2d6c9d21aa3d470866a3091bf
https://doi.org/10.1016/j.semcancer.2004.08.001
https://doi.org/10.1016/j.semcancer.2004.08.001
Publikováno v:
Biological Sciences Publications
Cathepsin B and pro-urokinase plasminogen activator (pro-uPA) localize to the caveolae of HCT 116 human colorectal carcinoma cells, an association mediated by active K-RAS. In this study, we established a stable HCT 116 cell line with a gene encoding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::876e13f1cdaf6b7a5168bd15ea484833
https://doi.org/10.1242/jcs.02278
https://doi.org/10.1242/jcs.02278
Publikováno v:
Journal of Biological Chemistry. 275:12806-12812
To study potential roles of plasma membrane-associated extracellular cathepsin B in tumor cell invasion and metastasis, we used the yeast two-hybrid system to screen for proteins that interact with human procathepsin B. The annexin II light chain (p1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::731842c34854495e8fc69690ca7f1995
https://doi.org/10.1074/jbc.275.17.12806
https://doi.org/10.1074/jbc.275.17.12806
Publikováno v:
Cellular Peptidases in Immune Functions and Diseases 2 ISBN: 0306463830
The lysosomal cysteineprotease cathepsin B has been implicated in tumor progression and metastasis in part due to its altered trafficking. In order to analyze the trafficking of cathepsin B in living cells, we utilized enhanced green fluorescent prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0402380e89290ccc75f35c44cc4dcbaa
https://doi.org/10.1007/0-306-46826-3_40
https://doi.org/10.1007/0-306-46826-3_40
Publikováno v:
Biological chemistry. 383(9)
Degradation of extracellular matrix proteins by proteases such as the cysteine protease cathepsin B is critical to malignant progression. We have established that procathepsin B presents on the surface of tumor cells through its interaction with the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b92eebe488956333e0126b94cae5ab2f
https://pubmed.ncbi.nlm.nih.gov/12437133
https://pubmed.ncbi.nlm.nih.gov/12437133
Publikováno v:
Biochimica et biophysica acta. 1477(1-2)
The cysteine protease cathepsin B is upregulated in a variety of tumors, particularly at the invasive edges. Cathepsin B can degrade extracellular matrix proteins, such as collagen IV and laminin, and can activate the precursor form of urokinase plas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::032d39a23225d4f4d173671df7641c3a
https://pubmed.ncbi.nlm.nih.gov/10708859
https://pubmed.ncbi.nlm.nih.gov/10708859
Autor:
Jianxin Mai, Adnan A. Elfarra, Anand Shivnani, Prakash Chinnaiyan, Lawrence H. Lash, Renee J. Krause
Publikováno v:
Biochemical pharmacology. 54(12)
The disposition of S-(6-purinyl)glutathione (6-PG) and its metabolites, including the antitumor agent 6-mercaptopurine (6-MP), was characterized in freshly isolated renal cortical cells from male F344 rats to assess the ability of the kidney to conve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51f222683c52d1be40f45f461318c25e
https://pubmed.ncbi.nlm.nih.gov/9393677
https://pubmed.ncbi.nlm.nih.gov/9393677
Publikováno v:
2006 Canadian Conference on Electrical & Computer Engineering; 2006, p616-619, 4p
Publikováno v:
Journal of Cell Science; 4/1/2005, Vol. 118 Issue 7, p1493-1503, 11p, 2 Color Photographs, 17 Graphs