Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Jiantong Jiao"'
Autor:
Hui Huang, Zhengyuan Huo, Jiantong Jiao, Wei Ji, Jin Huang, Zheng Bian, Bin Xu, Junfei Shao, Jun Sun
Publikováno v:
Cancer Cell International, Vol 22, Iss 1, Pp 1-15 (2022)
Abstract Background Gliomas are the most common primary malignant tumours of the central nervous system (CNS). To improve the prognosis of glioma, it is necessary to identify molecular markers that may be useful for glioma therapy. HOXC6, an importan
Externí odkaz:
https://doaj.org/article/1a48aafb94a34e348996d05f27eb3098
Publikováno v:
Journal of Integrative Neuroscience, Vol 22, Iss 6, p 144 (2023)
Background: Experimental investigations have reported the efficacy of marrow mesenchymal stem cell-derived exosomes (MSC-Exos) for the treatment of ischemic stroke. The therapeutic mechanism, however, is still unknown. The purpose of the study is to
Externí odkaz:
https://doaj.org/article/41040291b7224d1bb7ea0a3885fe7108
Autor:
Zheng Bian, Wei Ji, Bin Xu, Zhengyuan Huo, Hui Huang, Jin Huang, Jiantong Jiao, Junfei Shao, Xiaolu Zhang
Publikováno v:
Cancer Cell International, Vol 21, Iss 1, Pp 1-15 (2021)
Abstract Glioma is the most common malignant primary brain tumour in adults. Despite improvements in neurosurgery and radiotherapy, the prognosis of glioma patients remains poor. One of the main limitations is that there are no proper clinical therap
Externí odkaz:
https://doaj.org/article/03396c3c365741488f84d3ed523ec40a
Autor:
Yaling Hu, Bo Zhang, Peihua Lu, Jingying Wang, Cheng Chen, Ying Yin, Quan Wan, Jingjing Wang, Jiantong Jiao, Xiangming Fang, Zhening Pu, Lingli Gong, Li Ji, Lingpeng Zhu, Rui Zhang, Jia Zhang, Xusheng Yang, Qing Wang, Zhaohui Huang, Jian Zou
Publikováno v:
Clinical and Translational Medicine, Vol 12, Iss 9, Pp n/a-n/a (2022)
Abstract Background NF‐κB signaling is widely linked to the pathogenesis and treatment resistance in cancers. Increasing attention has been paid to its anti‐oncogenic roles, due to its key functions in cellular senescence and the senescence‐as
Externí odkaz:
https://doaj.org/article/1878f5f2a8304ded8aac5a572702bc6d
Autor:
Jingjing Wang, Zixuan Huang, Li Ji, Cheng Chen, Quan Wan, Yu Xin, Zhening Pu, Koukou Li, Jiantong Jiao, Ying Yin, Yaling Hu, Lingli Gong, Rui Zhang, Xusheng Yang, Xiangming Fang, Mei Wang, Bo Zhang, Junfei Shao, Jian Zou
Publikováno v:
Advanced Science, Vol 9, Iss 26, Pp n/a-n/a (2022)
Abstract Sustained activation of signal transducer and activator of transcription 3 (STAT3) is a critical contributor in tumorigenesis and chemoresistance, thus making it an attractive cancer therapeutic target. Here, SH2 domain‐containing adapter
Externí odkaz:
https://doaj.org/article/c4a8974d0ce84d6aa7db2c50f496cfc3
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-14 (2021)
Abstract Background The epidermal growth factor receptor (EGFR) family belongs to the transmembrane protein receptor of the tyrosine kinase I subfamily and has 4 members: EGFR/ERBB1, ERBB2, ERBB3, and ERBB4. The EGFR family is closely related to the
Externí odkaz:
https://doaj.org/article/67acf713b52043d596c2f6f93c20b698
Publikováno v:
Cancer Cell International, Vol 20, Iss 1, Pp 1-11 (2020)
Abstract Long noncoding RNAs (lncRNAs) are composed of > 200 nucleotides; they lack the ability to encode proteins but play important roles in a variety of human tumors. A large number of studies have shown that dysregulated expression of lncRNAs is
Externí odkaz:
https://doaj.org/article/a09dcbeb5cb84bd1bda7046d93ac4dbc
Autor:
Wei Ji, Yuankun Liu, Bin Xu, Jie Mei, Chao Cheng, Yong Xiao, Kun Yang, Weiyi Huang, Jiantong Jiao, Hongyi Liu, Junfei Shao
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Signal transducer and activator of transcription (STAT) family genes—of which there are seven members: STAT1, STAT2, STAT3, STAT4, STAT5A, STAT5B, and STAT6—have been associated with the progression of multiple cancers. However, their prognostic
Externí odkaz:
https://doaj.org/article/6cbe003fd47147bab1a5ae29daa40755
Autor:
Jiantong Jiao, Rui Zhang, Zheng Li, Ying Yin, Xiangming Fang, Xiaopeng Ding, Ying Cai, Shudong Yang, Huijun Mu, Da Zong, Yuexin Chen, Yansong Zhang, Jian Zou, Junfei Shao, Zhaohui Huang
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
In glioma STAT3 signaling contributes to gliomagenesis. Here, the authors show that Smad6 expression correlates with poor survival and is overexpressed in glioma cells, and regulates STAT3 activity via negatively regulating PIAS3.
Externí odkaz:
https://doaj.org/article/6bf4d49429d84fb48d663f6dd8ad532c
Autor:
Lingli Gong, Daxing Xu, Zhening Pu, Bo Zhang, Ying Yin, Li Ji, Jingjing Wang, Yaling Hu, Jiao Meng, Rui Zhang, Xiangming Fang, Jiantong Jiao, Jian Zou
Aberrant post-translational modification (PTM) is a key molecular event inciting p53 tumor suppressor function loss or transformation. Here, we report that p53 acetylation, independent of the overall level of p53 expression, predicts improved surviva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc8b09ea844bab950103a16a2244faff
https://doi.org/10.21203/rs.3.rs-2325817/v1
https://doi.org/10.21203/rs.3.rs-2325817/v1
