Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Jianting Zheng"'
Autor:
Zhihong Xiao, Jinyin Zha, Xu Yang, Tingting Huang, Shuxin Huang, Qi Liu, Xiaozheng Wang, Jie Zhong, Jianting Zheng, Rubing Liang, Zixin Deng, Jian Zhang, Shuangjun Lin, Shaobo Dai
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Modulation of protein function through allosteric regulation is central in biology, but biomacromolecular systems involving multiple subunits and ligands may exhibit complex regulatory mechanisms at different levels, which remain poorly unde
Externí odkaz:
https://doaj.org/article/f12afcd0d3fe4a8aa04a442de2c9aa0d
Autor:
Zhiqiang Hao, Qiang Guo, Yuanyuan Feng, Zihan Zhang, Tiantian Li, Zhixin Tian, Jianting Zheng, Lin-Tai Da, Wenjie Peng
Publikováno v:
JACS Au, Vol 3, Iss 8, Pp 2144-2155 (2023)
Externí odkaz:
https://doaj.org/article/75229d6c27b7461cb9b115f146cc5dd4
Autor:
Jianhua Wei, Xuan Zhang, Yucong Zhou, Xingnuo Cheng, Zhi Lin, Mancheng Tang, Jianting Zheng, Binju Wang, Qianjin Kang, Linquan Bai
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Carbamoyltransferases are a class of enzymes catalyzing carbamoylation of primary and secondary metabolites. Here, the authors show the molecular structure of the ansamycin-modifying carbamoyltransferase GdmN and repurpose the enzyme for the iterativ
Externí odkaz:
https://doaj.org/article/9185b2d2a478438daaeaf5e65afc3193
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-11 (2022)
Structural analyses of a Streptomyces viridochromogenes product template (PT) domain suggests molecular and functional similarities with known fungal PTs involved in polyketide synthase activity.
Externí odkaz:
https://doaj.org/article/562e56a57efc4dab905aea1c8bba314e
Autor:
Ruoyan Liu, Xiaoyu Chen, Fujie Zhao, Yixuan Jiang, Zhenguo Lu, Huining Ji, Yuanyuan Feng, Junqiang Li, Heng Zhang, Jianting Zheng, Jing Zhang, Youbao Zhao
Publikováno v:
Journal of Fungi, Vol 9, Iss 6, p 672 (2023)
The Complex of Proteins Associated with Set1 (COMPASS) methylates lysine K4 on histone H3 (H3K4) and is conserved from yeast to humans. Its subunits and regulatory roles in the meningitis-causing fungal pathogen Cryptococcus neoformans remain unknown
Externí odkaz:
https://doaj.org/article/dac05a0108604ef99c876203de43d156
Publikováno v:
Molecules, Vol 27, Iss 19, p 6405 (2022)
Chlorothricin (CHL) belongs to a spirotetronate antibiotic family produced by Streptomyces antibioticus that inhibits pyruvate carboxylase and malate dehydrogenase. For the biosynthesis of CHL, ChlB3 plays a crucial role by introducing the 6-methylsa
Externí odkaz:
https://doaj.org/article/96412e05e9124fa7b0193145f6ec208a
Publikováno v:
Synthetic and Systems Biotechnology, Vol 4, Iss 1, Pp 10-15 (2019)
The highly reducing iterative polyketide synthases responsible for lovastatin biosynthesis contains a section homologous to condensation (CON) domain observed in nonribosomal peptide synthetases (NRPSs). In the present study, we expressed the isolate
Externí odkaz:
https://doaj.org/article/9db94a60d1734b6491095ba9a7764a01
Publikováno v:
ACS Chemical Biology. 18:141-150
Pyridomycin is a potent antimycobacterial natural product by specifically inhibiting InhA, a clinically validated antituberculosis drug discovery target. Pyridyl moieties of pyridomycin play an essential role in inhibiting InhA by occupying the reduc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef2217b30f5f6d4c2c826d0135b90e4e
https://doi.org/10.1021/acschembio.2c00773
https://doi.org/10.1021/acschembio.2c00773
Autor:
Zhao, Ruoyan Liu, Xiaoyu Chen, Fujie Zhao, Yixuan Jiang, Zhenguo Lu, Huining Ji, Yuanyuan Feng, Junqiang Li, Heng Zhang, Jianting Zheng, Jing Zhang, Youbao
Publikováno v:
Journal of Fungi; Volume 9; Issue 6; Pages: 672
The Complex of Proteins Associated with Set1 (COMPASS) methylates lysine K4 on histone H3 (H3K4) and is conserved from yeast to humans. Its subunits and regulatory roles in the meningitis-causing fungal pathogen Cryptococcus neoformans remain unknown
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::38bff30e603501e0e65b69d0bdaa6d37
Publikováno v:
Nucleic Acids Research. 50:8363-8376
Streptomyces coelicolor (Sc) is a model organism of actinobacteria to study morphological differentiation and production of bioactive metabolites. Sc zinc uptake regulator (Zur) affects both processes by controlling zinc homeostasis. It activates tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cc9df4b9ee45bc0c158e60d09b8b272
https://doi.org/10.1093/nar/gkac627
https://doi.org/10.1093/nar/gkac627