Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Jiansong Xie"'
Autor:
Jiamiao Lu, Jasper Lee, Eric Yuan, Devin L. Wakefield, Matt Kanke, Danielle Pruitt, Jose Barreda, Ingrid C. Rulifson, Jiansong Xie, John Ferbas, Jason Long, Bryan Meade, Oliver Homann, Wei Guo, Tina Gomes, Hong Zhou, Bin Wu, Jixin Cui, Songli Wang
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 35, Iss 4, Pp 102335- (2024)
Small interfering RNAs (siRNAs) hold considerable therapeutic potential to selectively silence previously “undruggable” disease-associated targets, offering new opportunities to fight human diseases. This therapeutic strategy, however, is limited
Externí odkaz:
https://doaj.org/article/65bae3facf284c1b8c31c8c6325702c1
Autor:
Joshua M. Tokuda, Jiansong Xie, Vibha Jawa, Jenn M. Hawkins, John Ferbas, Nathan H. Joh, Marisa K. Joubert
Publikováno v:
Journal of pharmaceutical sciences. 111(4)
Subcutaneous (SubQ) injection is a common administration route for biotherapeutics. However, limited tools are available for understanding the dynamic relationships between drug products and resident cells following injection. Advances in tissue engi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26dbbdf1768f3adcd4932214be6187d9
https://pubmed.ncbi.nlm.nih.gov/35139332
https://pubmed.ncbi.nlm.nih.gov/35139332
Autor:
John Ferbas, Francis Kinderman, Johnathan Herskovitz, Nathan H. Joh, Vibha Jawa, Marisa K. Joubert, Jennifer Malella, Brittany Yerby, Helen J. McBride, Jiansong Xie
Publikováno v:
Journal of Pharmaceutical Sciences. 108:1953-1963
Antibody therapeutics with poor solubility in the subcutaneous matrix may carry unintended risks when administered to patients. The objective of this work was to estimate the risk of antibodies that precipitate in vitro at neutral pH by determining t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6215f8adcbb8e99e195b17a08839751
https://doi.org/10.1016/j.xphs.2019.01.015
https://doi.org/10.1016/j.xphs.2019.01.015
Autor:
Peng Li, Joanne T. Hulme, Helen J. McBride, Kim Merriam, Jiansong Xie, Alice Bakker, Hong Sun, Anielka Montalvan, Richard Smith, John E. Sims, Roy A. Black, Kevin Moore, Christopher A. Gabel, Natalia Grinberg, James B. Rottman, Angela Willee, Ryan Case, Amy N. Duguay, Warren N. D'Souza, Bo-Rin Park Yoon, Bin Fan, Benjamin M. Alba, Maria Rosalyn Dayao, Melissa Thomas, Khue Dang
Publikováno v:
Journal of Orthopaedic Research.
Designing drugs to treat diseases associated with articular joints, particularly those targeting chondrocytes, is challenging due to unique local environmental constraints including the avascular nature of cartilage, the absence of a closed joint com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c068c3006731a82f743ddf67cf1d28e5
https://doi.org/10.1002/jor.23756
https://doi.org/10.1002/jor.23756
Autor:
Joanne T, Hulme, Warren N, D'Souza, Helen J, McBride, Bo-Rin Park, Yoon, Angela M, Willee, Amy, Duguay, Melissa, Thomas, Bin, Fan, Maria Rosalyn, Dayao, James B, Rottman, Kim, Merriam, Jiansong, Xie, Richard, Smith, Benjamin M, Alba, Ryan B, Case, Khue, Dang, Anielka, Montalvan, Natalia, Grinberg, Hong, Sun, Roy A, Black, Christopher A, Gabel, John E, Sims, Kevin, Moore, Alice, Bakker, Peng, Li
Publikováno v:
Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 36(4)
Designing drugs to treat diseases associated with articular joints, particularly those targeting chondrocytes, is challenging due to unique local environmental constraints including the avascular nature of cartilage, the absence of a closed joint com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::841e1d28a802cc8283200513466ba970
https://pubmed.ncbi.nlm.nih.gov/28971529
https://pubmed.ncbi.nlm.nih.gov/28971529
Autor:
Hua Pei, Sarah F. Hamm-Alvarez, Yin Jie Chen, Guoqing Zhang, Cassandra L. Fraser, Jiansong Xie, Janette Contreras
Publikováno v:
ACS Nano. 4:2735-2747
In this study, nanoparticles based on difluoroboron dibenzoylmethane-poly(lactic acid) (BF(2)dbmPLA) are prepared. Polylactic acid or polylactide is a commonly used degradable polymer, while the boron dye possesses a large extinction coefficient, hig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bb4e420e2a298ef0d43291a8f130c7d
https://doi.org/10.1021/nn901385y
https://doi.org/10.1021/nn901385y
Autor:
Jiansong Xie, Jonathon Lo, Sarah F. Hamm-Alvarez, Kye-Il Joo, Chi-Lin Lee, Pin Wang, Yuning Lei
Publikováno v:
ACS Nano. 2:1553-1562
This study reports a general method of labeling enveloped viruses with semiconductor quantum dots (QDs) for use in single virus trafficking studies. Retroviruses, including human immunodeficiency virus (HIV), could be successfully tagged with QDs thr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::759d2f6ad266bb01c88d5cede214e887
https://doi.org/10.1021/nn8002136
https://doi.org/10.1021/nn8002136
Autor:
Sarah F. Hamm-Alvarez, Kelvin G. M. Brockbank, Katja Schenke-Layland, Jiansong Xie, W. Robb MacLellan, Zhen Zhen Chen
Publikováno v:
Cell and Tissue Banking. 9:299-307
Cartilage damage was studied using non-invasive multiphoton-excited autofluorescence and quantitative second harmonic generation (SHG) microscopy. Two cryopreservation techniques based upon freezing and vitrification methods, respectively, were emplo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::595b0044cbae453349c962240b5fbd90
https://doi.org/10.1007/s10561-008-9070-7
https://doi.org/10.1007/s10561-008-9070-7
Autor:
Sarah F. Hamm-Alvarez, Lali K. Medina-Kauwe, Kim Dh, Altan Rentsendorj, John J. Rossi, M. MacVeigh, Jiansong Xie, Sam Bass, Hasmik Agadjanian
Publikováno v:
Gene Therapy. 13:821-836
The adenovirus (Ad) penton base protein facilitates viral infection by binding cell surface integrins, triggering receptor-mediated endocytosis and mediating endosomal penetration. Given these multiple functions, recombinant penton base proteins have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76c214eb8e1bbaebcf8259e7f4b81851
https://doi.org/10.1038/sj.gt.3302729
https://doi.org/10.1038/sj.gt.3302729
Publikováno v:
Gene Therapy. 12:1734-1751
Nonviral vectors continue to be attractive alternatives to viruses due to their low toxicity and immunogenicity, lack of pathogenicity, and ease of pharmacologic production. However, nonviral vectors also continue to suffer from relatively low levels
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8326e9b296f280916d0af18630a208b
https://doi.org/10.1038/sj.gt.3302592
https://doi.org/10.1038/sj.gt.3302592