Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Jianshu Xie"'
Autor:
Daisuke Iijima, Hiroshi Sugama, Yoichi Takahashi, Miki Hirai, Yuko Togashi, Jianshu Xie, Jingkang Shen, Ying Ke, Hidenori Akatsuka, Takayuki Kawaguchi, Kei Takedomi, Akiko Kashima, Masashi Nishio, Yosuke Inui, Hikaru Yoneda, Guangxin Xia, Toru Iijima
Publikováno v:
Journal of Medicinal Chemistry. 65:10882-10897
Renin is the rate-limiting enzyme in the renin-angiotensin-aldosterone system (RAAS) which regulates blood pressure and renal function and hence is an attractive target for the treatment of hypertension and cardiovascular/renal diseases. However, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a7d118a6f7d7ab8858123b81a9c5444
https://doi.org/10.1021/acs.jmedchem.2c00834
https://doi.org/10.1021/acs.jmedchem.2c00834
Autor:
Daisuke Iijima, Hiroshi Sugama, Nobumasa Awai, Yoichi Takahashi, Yuko Togashi, Tohru Takebe, Jianshu Xie, Jingkang Shen, Ying Ke, Hidenori Akatsuka, Takayuki Kawaguchi, Kei Takedomi, Akiko Kashima, Masashi Nishio, Yosuke Inui, Hikaru Yoneda, Guangxin Xia, Toru Iijima
Publikováno v:
ACS medicinal chemistry letters. 13(8)
The renin-angiotensin-aldosterone system (RAAS) plays a key role in the regulation of blood pressure. Renin, the first and rate-limiting enzyme of the RAAS, is an attractive target for the treatment of hypertension and cardiovascular/renal diseases.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a81141cb66d003b8b8e48a18c4a8af4
https://pubmed.ncbi.nlm.nih.gov/35978678
https://pubmed.ncbi.nlm.nih.gov/35978678
Autor:
Jianshu Xie, Wen-yuan Yu, Ming-Wei Wang, Xue-yuan Jiang, Dexu Zhu, Mutsumi Muramatsu, Li-xia Yang, Ling Zhou
Publikováno v:
Acta pharmacologica Sinica. 29(2)
Aim: The aim of the present study was to design, synthesize, and evaluate novel antibacterial agents, derivatives of aryl-4-guanidinomethylbenzoate and N-aryl-4-guanidinomethylbenzamide. Methods: A total of 44 derivatives of aryl-4-guanidinomethylben
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa4b7176960a14db85f920d71e829d9e
https://pubmed.ncbi.nlm.nih.gov/18215358
https://pubmed.ncbi.nlm.nih.gov/18215358