Zobrazeno 1 - 10
of 163
pro vyhledávání: '"Jiansheng, Xie"'
Autor:
Haidong Wang, Jun Lou, Hao Liu, Yunlong Liu, Binbin Xie, Wei Zhang, Jiansheng Xie, Hongming Pan, Weidong Han
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Tumor-associated macrophages play a crucial role in the tumor microenvironment. Tripartite motif 59 (TRIM59), a member of the tripartite motif (TRIM) family, is known to be associated with immunological diseases and macrophage activation. Th
Externí odkaz:
https://doaj.org/article/04f9abbd5d21445996bacafe81bde027
Autor:
Hao Liu, Jun Lou, Yunlong Liu, Zhen Liu, Jiansheng Xie, Jiachun Sun, Hongming Pan, Weidong Han
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 28, Iss , Pp 35-46 (2022)
Colitis-associated cancer (CAC) is closely related to chronic inflammation, whose underlying molecular mechanism, however, has not been elaborated comprehensively. In the current study, an investigation was conducted on the role of autophagy in the i
Externí odkaz:
https://doaj.org/article/121df64a99094a6093a5daa160a720f5
Autor:
Xiaojing Liang, Jiansheng Xie, Hao Liu, Rongjie Zhao, Wei Zhang, Haidong Wang, Hongming Pan, Yubin Zhou, Weidong Han
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 14, Iss 1, Pp 193-217 (2022)
Background & Aims: As an indispensable component of store-operated Ca2+ entry, stromal interaction molecule 1 (STIM1) is known to promote colorectal cancer and T-cell–mediated inflammatory diseases. However, whether the intestinal mucosal STIM1 is
Externí odkaz:
https://doaj.org/article/2d84669030264ab68420a95f4e59d60b
Publikováno v:
Molecular Therapy: Oncolytics, Vol 23, Iss , Pp 515-530 (2021)
Metastasis is considered the leading cause of cancer death due to the limited possibilities to therapeutically target this process. How the ubiquitination machinery contributes to metastasis remains underexplored. Angio-associated migratory cell prot
Externí odkaz:
https://doaj.org/article/bf1f2c41243e4b9aaa1f98caaa642c12
Autor:
Hui Wang, Caiqun Luo, Xiaoxia Wu, Jianming Zhang, Zhiyong Xu, Yang Liu, Bohong Li, Jing Li, Jiansheng Xie
Publikováno v:
Reproductive Biology and Endocrinology, Vol 19, Iss 1, Pp 1-11 (2021)
Abstract Background Various circular RNAs (circRNAs) are dysregulated in the placenta of fetal growth restriction (FGR) fetuses, but their roles and regulatory mechanisms have not been fully elucidated. Herein, we aimed to elucidate the role of hsa_c
Externí odkaz:
https://doaj.org/article/d6c8b17512b74c238777479c306f1455
Autor:
Ying Hao, Yang Liu, Jingxin Yang, Xingping Li, Fuwei Luo, Qian Geng, Suli Li, Peining Li, Weiqing Wu, Jiansheng Xie
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Background: Phelan–McDermid syndrome (PMS), caused by deletions at 22q13.3 and pathogenic variants in the SHANK3 gene, is a rare developmental disorder characterized by hypotonia, developmental delay (DD), intellectual disability (ID), autism spect
Externí odkaz:
https://doaj.org/article/a87fc3e457044a9f96bceb96ffa5d1ec
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 24, Iss , Pp 264-273 (2021)
Patients with inflammatory bowel disease are at increased risk for colitis-associated colorectal cancer (CAC). Therefore, controlling intestinal inflammation is a key therapeutic strategy for CAC. MicroRNAs (miRNAs or miRs) are a family of small nonc
Externí odkaz:
https://doaj.org/article/628afbdb37ca4b37967b9262b5f00a34
Publikováno v:
Clinical Case Reports, Vol 10, Iss 6, Pp n/a-n/a (2022)
Abstract Here we report a case of a 16q24.3 microdeletion KBG syndrome (KBGS) in a fetus. The absence of a well‐defined phenotype poses a challenge for genetic diagnosis. This report demonstrated that the high‐risk chromosome 21 trisomy could be
Externí odkaz:
https://doaj.org/article/6c52e84312a54f38a5567815f913df7b
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 10, Iss 5, Pp n/a-n/a (2022)
Abstract Background Bainbridge‐Ropers syndrome (BRPS, OMIM #615485) was first identified in 2013 by Bainbridge et al. and is a neurodevelopment disorder characterized by failure to thrive, facial dysmorphism and severe developmental delay. BRPS is
Externí odkaz:
https://doaj.org/article/3a42bab12bec48c18804ff34151d9504
Autor:
Jiansheng Xie, Guolin Ma, Lijuan Zhou, Lian He, Zhao Zhang, Peng Tan, Zixian Huang, Shaohai Fang, Tianlu Wang, Yi‐Tsang Lee, Shufan Wen, Stefan Siwko, Liuqing Wang, Jindou Liu, Yangchun Du, Ningxia Zhang, Xiaoxuan Liu, Leng Han, Yun Huang, Rui Wang, Youjun Wang, Yubin Zhou, Weidong Han
Publikováno v:
Advanced Science, Vol 9, Iss 11, Pp n/a-n/a (2022)
Abstract Deregulated store‐operated calcium entry (SOCE) mediated by aberrant STIM1‐ORAI1 signaling is closely implicated in cancer initiation and progression. Here the authors report the identification of an alternatively spliced variant of STIM
Externí odkaz:
https://doaj.org/article/733b58bf5ebb41d489d9290c72d77544