Zobrazeno 1 - 10
of 178
pro vyhledávání: '"Jianru Li"'
Autor:
Wei Jiang, Qing Li, Ruofei Zhang, Jianru Li, Qianyu Lin, Jingyun Li, Xinyao Zhou, Xiyun Yan, Kelong Fan
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Nanomedicine-based anti-neuroinflammation strategy has become a promising dawn of Parkinson’s disease (PD) treatment. However, there are significant gaps in our understanding of the therapeutic mechanisms of antioxidant nanomedicines conce
Externí odkaz:
https://doaj.org/article/10b847de1b3f427a802f494890fcba43
Autor:
Huaijun Chen, Chaoran Xu, Hanhai Zeng, Zhihua Zhang, Ning Wang, Yinghan Guo, Yonghe Zheng, Siqi Xia, Hang Zhou, Xiaobo Yu, Xiongjie Fu, Tianchi Tang, Xinyan Wu, Zihang Chen, Yucong Peng, Jing Cai, Jianru Li, Feng Yan, Chi Gu, Gao Chen, Jingyin Chen
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-17 (2023)
Abstract Background Subarachnoid hemorrhage (SAH) is an uncommon type of potentially fatal stroke. The pathophysiological mechanisms of brain injury remain unclear, which hinders the development of drugs for SAH. We aimed to investigate the pathophys
Externí odkaz:
https://doaj.org/article/4e90c1634dec43a8a8d3328197469c1d
Autor:
Guilin Xiang, Cunying Xu, Shuxian Wang, Jianru Li, Wenkang Chen, Daiyun Gu, Qibo zhang, Yixin Hua
Publikováno v:
Electrochemistry Communications, Vol 157, Iss , Pp 107619- (2023)
The electrodeposition of neodymium was investigated in betaine-ethylene glycol (Bet-EG) deep eutectic solvent (DES) containing neodymium oxide (Nd2O3) at different temperatures ranging from 353 K to 373 K. The electrochemical behavior of Nd2O3 dissol
Externí odkaz:
https://doaj.org/article/8d092d94cc4f44b7b1bfa79c040fe563
Publikováno v:
Journal of Advanced Research, Vol 44, Iss , Pp 185-199 (2023)
Introduction: Microglia and macrophages participate in hematoma clearance after intracerebral hemorrhage (ICH), thereby facilitating tissue restoration and neurological recovery. Triggering receptor expressed on myeloid cells 2 (Trem2) has been indic
Externí odkaz:
https://doaj.org/article/d4789282e96f48499fb4bfc57712f287
Autor:
Xiongjie Fu, Guoyang Zhou, Xinyan Wu, Chaoran Xu, Hang Zhou, Jianfeng Zhuang, Yucong Peng, Yang Cao, Hanhai Zeng, Yin Li, Jianru Li, Liansheng Gao, Gao Chen, Lin Wang, Feng Yan
Publikováno v:
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-16 (2021)
Abstract Background White matter injury (WMI) is a major neuropathological event associated with intracerebral hemorrhage (ICH). P2X purinoreceptor 4 (P2X4R) is a member of the P2X purine receptor family, which plays a crucial role in regulating WMI
Externí odkaz:
https://doaj.org/article/272022f71bab4ea99ba55e3592f3aacc
Autor:
Hang Zhou, Libin Hu, Jianru Li, Wu Ruan, Yang Cao, Jianfeng Zhuang, Hangzhe Xu, Yucong Peng, Zhongyuan Zhang, Chaoran Xu, Qian Yu, Yin Li, Zhangqi Dou, Junwen Hu, Xinyan Wu, Xiaobo Yu, Chi Gu, Shenglong Cao, Feng Yan, Gao Chen
Publikováno v:
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-17 (2021)
Abstract Background Complex changes in the brain microenvironment following traumatic brain injury (TBI) can cause neurological impairments for which there are few efficacious therapeutic interventions. The reactivity of astrocytes is one of the keys
Externí odkaz:
https://doaj.org/article/9d21e5d648dd45b4990e27c594082166
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
Neurovascular units (NVUs) are basic functional units in the central nervous system and include neurons, astrocytes and vascular compartments. Ischemic stroke triggers not only neuronal damage, but also dissonance of intercellular crosstalk within th
Externí odkaz:
https://doaj.org/article/e58fa21d24f2451e82ec930c50eb1ba0
Autor:
Xiaobo Yu, Xiongjie Fu, Xinyan Wu, Wenwen Tang, Lei Xu, Libin Hu, Chaoran Xu, Hang Zhou, Guoyang Zhou, Jianru Li, Shenglong Cao, Jiang Liu, Feng Yan, Lin Wang, Fuyi Liu, Gao Chen
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2022)
The gut microbiota plays a key role in regulating intracerebral hemorrhage (ICH)-induced neuroinflammation. The anti-neuroinflammatory effects of metformin (Met) have been reported in many central nervous system (CNS) diseases. However, whether Met r
Externí odkaz:
https://doaj.org/article/149fc42fa71147b78e9c811456d2dc12
Autor:
Yucong Peng, Jianfeng Zhuang, Guangyu Ying, Hanhai Zeng, Hang Zhou, Yang Cao, Huaijun Chen, Chaoran Xu, Xiongjie Fu, Hangzhe Xu, Jianru Li, Shenglong Cao, Jingyin Chen, Chi Gu, Feng Yan, Gao Chen
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-20 (2020)
Abstract Background Neuroinflammation is closely associated with the poor prognosis in subarachnoid hemorrhage (SAH) patients. This study was aimed to determine the role of stimulator of IFN genes (STING), an essential regulator to innate immunity, i
Externí odkaz:
https://doaj.org/article/c0dc07953fd740abb1e2fad8df00e887
Autor:
Bing Qin, Yucong Peng, Chen Zhong, Yong Cai, Shengjun Zhou, Huaijun Chen, Jianfeng Zhuang, Hanhai Zeng, Chaoran Xu, Hangzhe Xu, Jianru Li, Guangyu Ying, Chi Gu, Gao Chen, Lin Wang
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2021)
Subarachnoid hemorrhage (SAH) is a devastating cerebrovascular disease with high mortality and disability. Aberrant neuroinflammation has been identified as a critical factor accounting for the poor prognosis of SAH patients. Mast cells (MCs), the se
Externí odkaz:
https://doaj.org/article/6fb3ba5b614b4039a69677453148c39c