Zobrazeno 1 - 10
of 570
pro vyhledávání: '"Jianrong Xu"'
Autor:
Ningyuan Wen, Dingzhong Peng, Xianze Xiong, Geng Liu, Guilin Nie, Yaoqun Wang, Jianrong Xu, Shaofeng Wang, Sishu Yang, Yuan Tian, Bei Li, Jiong Lu, Nansheng Cheng
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 9, Iss 1, Pp 1-13 (2024)
Abstract Cholangiocarcinoma (CCA) is a highly malignant biliary tract cancer with currently suboptimal diagnostic and prognostic approaches. We present a novel system to monitor CCA using exosomal circular RNA (circRNA) via serum and biliary liquid b
Externí odkaz:
https://doaj.org/article/158590e20d8844dca025e9a0305062ed
Autor:
Zhenxi Li, Xinghai Yang, Ruifeng Fu, Zhipeng Wu, Shengzhao Xu, Jian Jiao, Ming Qian, Long Zhang, Chunbiao Wu, Tianying Xie, Jiqiang Yao, Zhixiang Wu, Wenjun Li, Guoli Ma, Yu You, Yihua Chen, Han-kun Zhang, Yiyun Cheng, Xiaolong Tang, Pengfei Wu, Gewei Lian, Haifeng Wei, Jian Zhao, Jianrong Xu, Lianzhong Ai, Stefan Siwko, Yue Wang, Jin Ding, Gaojie Song, Jian Luo, Mingyao Liu, Jianru Xiao
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Osteoclasts are over-activated as we age, which results in bone loss. Src deficiency in mice leads to severe osteopetrosis due to a functional defect in osteoclasts, indicating that Src function is essential in osteoclasts. G-protein-coupled
Externí odkaz:
https://doaj.org/article/0890b5c3600c4d14b91eb72f87712feb
Autor:
Shijie Xu, Jian Chen, Fang Yang, Zhihao Yang, Jianrong Xu, Lanyue Wang, Lina Bian, Lihua Liu, Xiaoyu Zhao, Yunshan Zhang
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 11 (2023)
Single-nucleotide polymorphism (SNP) plays a key role in the carcinogenesis of the human genome, and understanding the intrinsic relationship between individual genetic variations and carcinogenesis lies heavily in the establishment of a precise and
Externí odkaz:
https://doaj.org/article/ddc5f29a1a17493fa635dd0b93621a5a
Autor:
Dayuan Wang, Xiao Gu, Xinyi Ma, Jun Chen, Qizhi Zhang, Zhihua Yu, Juan Li, Meng Hu, Xiaofang Tan, Yuyun Tang, Jianrong Xu, Minjun Xu, Qingxiang Song, Huahua Song, Gan Jiang, Zaiming Tang, Xiaoling Gao, Hongzhuan Chen
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 13, Iss 2, Pp 834-851 (2023)
Microglial surveillance plays an essential role in clearing misfolded proteins such as amyloid-beta, tau, and α-synuclein aggregates in neurodegenerative diseases. However, due to the complex structure and ambiguous pathogenic species of the misfold
Externí odkaz:
https://doaj.org/article/68830f1934e244a9a3427fb520505ffc
Autor:
Depei Kong, Chen Ye, Chenxi Zhang, Xiaochen Sun, Fubo Wang, Rui Chen, Guangan Xiao, Shipeng He, Jianrong Xu, Xiwu Rao, Jianzhong Ai, Xu Gao, Hong Li, Li Su
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-21 (2023)
Abstract Background Bone is the most common site of metastasis of prostate cancer (PCa). PCa invasion leads to a disruption of osteogenic-osteolytic balance and causes abnormal bone formation. The interaction between PCa and bone stromal cells, espec
Externí odkaz:
https://doaj.org/article/40cffb13009346fea7f3939667e3d18d
Autor:
Xiaobin Wei, Li Zhu, Yanyan Zeng, Ke Xue, Yongming Dai, Jianrong Xu, Guiqin Liu, Fang Liu, Wei Xue, Dongmei Wu, Guangyu Wu
Publikováno v:
Cancer Imaging, Vol 22, Iss 1, Pp 1-11 (2022)
Abstract Background To evaluate the performance of diffusion-relaxation correlation spectrum imaging (DR-CSI) with support vector machine (SVM) in detecting prostate cancer (PCa). Methods In total, 114 patients (mean age, 66 years, range, 48–87 yea
Externí odkaz:
https://doaj.org/article/34685aba839c4e349c6bb1899a94ca07
Autor:
Jingyi Bai, Xi Li, Jun Zhao, Huifang Zong, Yuan Yuan, Lei Wang, Xiaoshuai Zhang, Yong Ke, Lei Han, Jianrong Xu, Buyong Ma, Baohong Zhang, Jianwei Zhu
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 3, p 1593 (2024)
Amyloidosis involves the deposition of misfolded proteins. Even though it is caused by different pathogenic mechanisms, in aggregate, it shares similar features. Here, we tested and confirmed a hypothesis that an amyloid antibody can be engineered by
Externí odkaz:
https://doaj.org/article/bca050be09ea4cb1a19f27d75f3ab83a
Autor:
Qian Zhang, Qingxiang Song, Renhe Yu, Antian Wang, Gan Jiang, Yukun Huang, Jun Chen, Jianrong Xu, Dayuan Wang, Hongzhuan Chen, Xiaoling Gao
Publikováno v:
Advanced Science, Vol 10, Iss 7, Pp n/a-n/a (2023)
Abstract Mitochondrial dysfunction has been recognized as the key pathogenesis of most neurodegenerative diseases including Alzheimer's disease (AD). The dysregulation of mitochondrial calcium ion (Ca2+) homeostasis and the mitochondrial permeability
Externí odkaz:
https://doaj.org/article/25083664f6594087bbb0c8b5c4d6d920
Autor:
Zhenlong Yu, Jian Gao, Xiaolei Zhang, Yulin Peng, Wenlong Wei, Jianrong Xu, Zhenwei Li, Chao Wang, Meirong Zhou, Xiangge Tian, Lei Feng, Xiaokui Huo, Min Liu, Mingliang Ye, De-an Guo, Xiaochi Ma
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/138785d275ab43e99a03ae178deb598a
Autor:
Zhenlong Yu, Jian Gao, Xiaolei Zhang, Yulin Peng, Wenlong Wei, Jianrong Xu, Zhenwei Li, Chao Wang, Meirong Zhou, Xiangge Tian, Lei Feng, Xiaokui Huo, Min Liu, Mingliang Ye, De-an Guo, Xiaochi Ma
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 7, Iss 1, Pp 1-13 (2022)
Abstract NEMO/IKKβ complex is a central regulator of NF-κB signaling pathway, its dissociation has been considered to be an attractive therapeutic target. Herein, using a combined strategy of molecular pharmacological phenotyping, proteomics and bi
Externí odkaz:
https://doaj.org/article/0359637a36874a6aaa5629eb0df2584d