Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Jianrao Lu"'
Publikováno v:
European Journal of Medical Research, Vol 29, Iss 1, Pp 1-12 (2024)
Abstract Background Renal fibrosis (RF) produced adverse effect on kidney function. Recently, intestinal dysbiosis is a key regulator that promotes the formation of renal fibrosis. This study will focus on exploring the protective mechanism of Kangxi
Externí odkaz:
https://doaj.org/article/18465f44a9ca42cc9093bf98bc335bc3
Publikováno v:
Renal Failure, Vol 46, Iss 1 (2024)
Background Renal fibrosis contributes to chronic renal failure and a decline in the quality of life. Bushen Huoxue (BSHX) formula is a Traditional Chinese Medicine used to treat chronic renal failure. However, its mechanisms of action remain unclear.
Externí odkaz:
https://doaj.org/article/bfc3a7ff76434276a4c7a797e8e2d312
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
ObjectiveThis study aims to conduct a detailed bibliometric and visual analysis of acute kidney injury (AKI) and immune-related research conducted over the past two decades, focusing on identifying emerging trends and key areas of interest.MethodsThe
Externí odkaz:
https://doaj.org/article/72a811cf5f754e96b6eec014ba3fa32e
Autor:
Lin Liao, Pengyu Tao, Qiming Xu, Wenhao Chen, Jie Chen, Weiwei Liu, Wenrui Liu, Jing Hu, Jianrao Lu
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 29, Iss 2, p 58 (2024)
Background: Pyroptosis is a critical form of cell death during the development of chronic kidney disease (CKD). Tripartite motif 6 (TRIM6) is an E3-ubiquitin ligase that participates in the progression renal fibrosis (RF). The aim of this study was t
Externí odkaz:
https://doaj.org/article/bf91b3cdb69c43778dfeb94d27dea47c
Autor:
Weiwei Liu, Yang Yi, Chuanfu Zhang, Baojuan Zhou, Lin Liao, Wenrui Liu, Jing Hu, Qiming Xu, Jie Chen, Jianrao Lu
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2021)
Renal fibrosis is considered as the final pathway of all types of kidney diseases, which can lead to the progressive loss of kidney functions and eventually renal failure. The mechanisms behind are diversified, in which the mammalian target of rapamy
Externí odkaz:
https://doaj.org/article/2080d928dce244028073c3fc37fc77d1
Autor:
Lin Liao, Jie Chen, Chuanfu Zhang, Yue Guo, Weiwei Liu, Wenrui Liu, Lianxiang Duan, Ziyang Liu, Jing Hu, Jianrao Lu
Publikováno v:
Frontiers in Molecular Biosciences, Vol 7 (2021)
Glomerular hypertrophy is an early morphological alteration in diabetic nephropathy. Cyclin-Dependent Kinases have been shown to be required for high glucose (HG)-induced hypertrophy; however, the upstream regulators of CDKN1B in glomerular hypertrop
Externí odkaz:
https://doaj.org/article/0cba0ec7ce2a4bbaa01a7dc910428464
Publikováno v:
In Biomedicine & Pharmacotherapy March 2018 99:306-312
Autor:
Xian Chen, Jianrao Lu
Publikováno v:
Journal of Biomaterials and Tissue Engineering. 13:241-249
To probe the role and specific mechanism of Bushen Huoxue Recipe in inhibiting renal fibrosis (RF), 150 healthy adult male Sprague-Dawley rats were randomized to sham operated group (SO group), model group (UUO group), conventional treatment group (U
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::32f60eafabccbe0c403019a4b95858c5
https://doi.org/10.1166/jbt.2023.3249
https://doi.org/10.1166/jbt.2023.3249
Autor:
jianrao Lu, jing Hu
β-sitosterol is a compound found in many plants and has a variety of biological activities, including immunomodulatory and anti-inflammatory activities. The purpose of this study is to test its anti-inflammatory ability through a mouse model of acut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::33d8f3f32c1a44519fba07386b2fe2c9
https://doi.org/10.21203/rs.3.rs-1402285/v1
https://doi.org/10.21203/rs.3.rs-1402285/v1
Autor:
Lin Liao, Lianxiang Duan, Yue Guo, Baojuan Zhou, Qiming Xu, Chuanfu Zhang, Weiwei Liu, Wenrui Liu, Ziyang Liu, Jing Hu, Jie Chen, Jianrao Lu
Publikováno v:
Molecular and cellular biochemistry. 477(12)
Hypoxia can cause Epithelial-mesenchymal transition (EMT) in renal tubular cells, and in turn, renal fibrosis. We tested the expression of TRIM46, a member of tripartite motif-containing (TRIM) family proteins, and mesenchymal markers under hypoxia.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0d86608e6444de7ba887e498120f52d
https://pubmed.ncbi.nlm.nih.gov/35670901
https://pubmed.ncbi.nlm.nih.gov/35670901