Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Jianqiao Yi"'
Autor:
Mengmeng Niu, Jing Xu, Yang Liu, Yuhuang Li, Tao He, Liangping Ding, Yajun He, Yong Yi, Fengtian Li, Rongtian Guo, Ya Gao, Rui Li, Luping Li, Mengyuan Fu, Qingyong Hu, Yangkun Luo, Chunyan Zhang, Kewei Qin, Jianqiao Yi, Shuhan Yu, Jian Yang, Hu Chen, Liang Wang, Zhonghan Li, Biao Dong, Shiqian Qi, Liang Ouyang, Yujun Zhang, Yang Cao, Zhi-Xiong Jim Xiao
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Aberrant EGFR activation is commonly found in non-small cell lung cancer (NSCLC). Here the authors show that E3 ubiquitin ligase FBXL2 targets EGFR and EGFR tyrosine kinase inhibitor (TKI)-resistant mutants for proteasome-mediated degradation to inhi
Externí odkaz:
https://doaj.org/article/02573bddb0d6479d8c98e3f6154fe92f
Autor:
Zhijun Luo, Yangkun Luo, Yong Yi, Deshi Chen, Jianqiao Yi, Wenhua Zhang, Hu Chen, Junjie Fei, Mengmeng Niu, Xiaokun Ren, Juan Ao, Zhi-Xiong Jim Xiao, Fengtian Li
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Oncogenic hotspot mutations in PIK3CA and overexpression of HER2 are known as a driving force for human breast cancer metastasis. AMPK is pivotal in maintaining cellular energy homeostasis. In this study, we demonstrate that transcriptio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18975d71389ab9f18aab70bede5801d7
http://europepmc.org/articles/PMC7148563
http://europepmc.org/articles/PMC7148563
Autor:
Yangkun Luo, Hu Chen, Mengyuan Fu, Yujun Zhang, Luping Li, Yajun He, Yuhuang Li, Jing Xu, Rongtian Guo, Zhonghan Li, Ya Gao, Liang Ouyang, Yang Liu, Shuhan Yu, Liangping Ding, Chunyan Zhang, Jianqiao Yi, Zhi-Xiong Jim Xiao, Yang Cao, Yong Yi, Mengmeng Niu, Biao Dong, Liang Wang, Fengtian Li, Kewei Qin, Jian Yang, Tao He, Shiqian Qi, Qingyong Hu, Rui Li
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Abnormal activation of epidermal growth factor receptor (EGFR) drives non-small cell lung cancer (NSCLC) development. EGFR mutations-mediated resistance to tyrosine-kinase inhibitors (TKIs) is a major hurdle for NSCLC treatment. Here, we show that F-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b1c52c790e8f0526eb9440d4629042b
https://pubmed.ncbi.nlm.nih.gov/34635651
https://pubmed.ncbi.nlm.nih.gov/34635651
Autor:
Hongli Gao, Jianqiao Yin, Ce Ji, Xiaopeng Yu, Jinqi Xue, Xin Guan, Shuang Zhang, Xun Liu, Fei Xing
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-22 (2023)
Abstract Tumors have evolved in various mechanisms to evade the immune system, hindering the antitumor immune response and facilitating tumor progression. Immunotherapy has become a potential treatment strategy specific to different cancer types by u
Externí odkaz:
https://doaj.org/article/a2388da6c7a544dbbfed463e0222ce30
Publikováno v:
Journal of Cancer
Metformin has been used as therapy for type 2 diabetes for many years. Clinical and basic evidence as indicated that metformin has anti-cancer activities. It has been well-established that metformin activates AMP-activated protein kinase (AMPK), whic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e927d5cdf8bbf03bdb0dbca2f1f9372
https://pubmed.ncbi.nlm.nih.gov/31258748
https://pubmed.ncbi.nlm.nih.gov/31258748
Autor:
Guanglei Chen, Xi Gu, Jinqi Xue, Xu Zhang, Xiaopeng Yu, Yu Zhang, Ailin Li, Yi Zhao, Guijin He, Meiyue Tang, Fei Xing, Jianqiao Yin, Xiaobo Bian, Ye Han, Shuo Cao, Chao Liu, Xiaofan Jiang, Keliang Zhang, Yan Xia, Huajun Li, Nan Niu, Caigang Liu, On behalf of the Northeastern Clinical Research Alliance of Oncology (NCRAO)
Publikováno v:
eLife, Vol 12 (2023)
Background: Emerging data have supported the immunostimulatory role of radiotherapy, which could exert a synergistic effect with immune checkpoint inhibitors (ICIs). With proven effective but suboptimal effect of ICI and chemotherapy in triple-negati
Externí odkaz:
https://doaj.org/article/4d40ffdb0c304d388f1adabf0f97596c
Autor:
Wenhua Zhang, Zhi-Xiong Xiao, Jianqiao Yi, Deshi Chen, Yuhuang Li, Tingting An, Juan Ao, Yong Yi, Zhiming Zhang
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 20, Iss 5, p 1161 (2019)
International Journal of Molecular Sciences, Vol 20, Iss 5, p 1161 (2019)
Cell–cell adhesion plays an important role in regulation of cell proliferation, migration, survival, and drug sensitivity. Metformin, a first line drug for type 2 diabetes, has been shown to possess anti-cancer activities. However, whether cell–c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5bfa4dbeb66b65c3e59c8d51180c666
https://doi.org/10.3390/ijms20051161
https://doi.org/10.3390/ijms20051161
Autor:
Yong Yi, Deshi Chen, Juan Ao, Wenhua Zhang, Jianqiao Yi, Xiaokun Ren, Junjie Fei, Fengtian Li, Mengmeng Niu, Hu Chen, Yangkun Luo, Zhijun Luo, Zhi-Xiong Jim Xiao
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 4/7/2020, Vol. 117 Issue 14, p8013-8021, 9p
Autor:
Haojie Wang1, Yanze Yang2, Xin Zhang1, Zhiwan Shu1, Fei Tong3, Qunhui Zhang4, Jianqiao Yi5 ncwdjd@163.com
Publikováno v:
Alternative Therapies in Health & Medicine. Jul/Aug2023, Vol. 29 Issue 5, p228-232. 5p.