Zobrazeno 1 - 10
of 168
pro vyhledávání: '"Jiannong Li"'
Autor:
Michael F. Emmons, Richard L. Bennett, Alberto Riva, Kanchan Gupta, Larissa Anastasio Da Costa Carvalho, Chao Zhang, Robert Macaulay, Daphne Dupéré-Richér, Bin Fang, Edward Seto, John M. Koomen, Jiannong Li, Y. Ann Chen, Peter A. Forsyth, Jonathan D. Licht, Keiran S. M. Smalley
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Melanomas can adopt multiple transcriptional states. Little is known about the epigenetic drivers of these cell states, limiting our ability to regulate melanoma heterogeneity. Here, we identify stress-induced HDAC8 activity as driving melan
Externí odkaz:
https://doaj.org/article/eaa6d6439c614e83a09975f61db4c4e0
Autor:
Paulo C Rodriguez, Zhihua Chen, Y Ann Chen, Lilit Karapetyan, Jiannong Li, Manali S Phadke, Jessica K Mandula, Peter A Forsyth, Keiran S M Smalley
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 12 (2023)
Background Although the anti-PD-1+LAG-3 and the anti-PD-1+CTLA-4 combinations are effective in advanced melanoma, it remains unclear whether their mechanisms of action overlap.Methods We used single cell (sc) RNA-seq, flow cytometry and IHC analysis
Externí odkaz:
https://doaj.org/article/4d56c2e227884da39b33d1663c170b41
Autor:
Yainyrette Rivera-Rivera, Geraldine Vargas, Neha Jaiswal, Angel Núñez-Marrero, Jiannong Li, Dung-Tsa Chen, Steven Eschrich, Marilin Rosa, Joseph O. Johnson, Julie Dutil, Srikumar P. Chellappan, Harold I. Saavedra
Publikováno v:
Cell Division, Vol 17, Iss 1, Pp 1-14 (2022)
Abstract Molecular epidemiology evidence indicates racial and ethnic differences in the aggressiveness and survival of breast cancer. Hispanics/Latinas (H/Ls) and non-Hispanic Black women (NHB) are at higher risk of breast cancer (BC)-related death r
Externí odkaz:
https://doaj.org/article/bc3caee0596a4f7ca187e7de2ddb60a7
Autor:
Daniel Jeong, Brian Morse, Stuart Lane Polk, Dung-Tsa Chen, Jiannong Li, Pamela Hodul, Barbara A. Centeno, James Costello, Kun Jiang, Sebastian Machado, Issam El Naqa, Paola T. Farah, Tri Huynh, Natarajan Raghunand, Shaffer Mok, Aamir Dam, Mokenge Malafa, Aliya Qayyum, Jason B. Fleming, Jennifer B. Permuth
Publikováno v:
Cancers, Vol 16, Iss 1, p 206 (2024)
BACKGROUND: While multiple cyst features are evaluated for stratifying pancreatic intraductal papillary mucinous neoplasms (IPMN), cyst size is an important factor that can influence treatment strategies. When magnetic resonance imaging (MRI) is used
Externí odkaz:
https://doaj.org/article/8eea7f4edd3c44709ae8fbf4da9f78fc
Autor:
Matthew Johnson, Jameel Muzaffar, Xuefeng Wang, Christine H Chung, Jose R Conejo-Garcia, Michael J Schell, Kedar Kirtane, Priyanka Bhateja, Marcelo Bonomi, Feifei Song, Jiannong Li, Sean J Yoder, Jose A Guevara-Patino, James W Rocco, Conor E Steuer, Nabil F Saba
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 6 (2022)
Externí odkaz:
https://doaj.org/article/5c07de39e3c8402aa41c38e7422c0643
Autor:
Zachary J. Thompson, Jamie K. Teer, Jiannong Li, Zhihua Chen, Eric A. Welsh, Yonghong Zhang, Noura Ayoubi, Zeynep Eroglu, Aik Choon Tan, Keiran S. M. Smalley, Yian Ann Chen
Publikováno v:
Cells, Vol 11, Iss 18, p 2894 (2022)
Although substantial progress has been made in treating patients with advanced melanoma with targeted and immuno-therapies, de novo and acquired resistance is commonplace. After treatment failure, therapeutic options are very limited and novel strate
Externí odkaz:
https://doaj.org/article/ac45d504ae06489ea9a0020319ae808d
Autor:
Yumeng Zhang, Premsai Kumar, Jacob J. Adashek, William P. Skelton, Jiannong Li, Aram Vosoughi, Jad Chahoud, Brandon J. Manley, Philippe E. Spiess
Publikováno v:
Cells, Vol 11, Iss 16, p 2505 (2022)
Modulating the cyclooxygenase 2 (COX-2) pathway has improved responses to immune checkpoint inhibitors (ICIs) in certain solid tumors, such as melanoma. Little is known about COX-2 inhibition in response to ICIs in metastatic renal cell carcinoma (mR
Externí odkaz:
https://doaj.org/article/32074deeaf034ef8853c0646073e31e0
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
BackgroundSignificant racial disparities in pancreatic cancer incidence and mortality rates exist, with the highest rates in African Americans compared to Non-Hispanic Whites and Hispanic/Latinx populations. Computer-derived quantitative imaging or
Externí odkaz:
https://doaj.org/article/baa977c5eb6e4d568beaf4015602f59e
Autor:
Inna Smalley, Eunjung Kim, Jiannong Li, Paige Spence, Clayton J. Wyatt, Zeynep Eroglu, Vernon K. Sondak, Jane L. Messina, Nalan Akgul Babacan, Silvya Stuchi Maria-Engler, Lesley De Armas, Sion L. Williams, Robert A. Gatenby, Y. Ann Chen, Alexander R.A. Anderson, Keiran S.M. Smalley
Publikováno v:
EBioMedicine, Vol 48, Iss , Pp 178-190 (2019)
Background: Melanoma is a heterogeneous tumour, but the impact of this heterogeneity upon therapeutic response is not well understood. Methods: Single cell mRNA analysis was used to define the transcriptional heterogeneity of melanoma and its dynamic
Externí odkaz:
https://doaj.org/article/7d086aa6efdb4ee5a9b2cf678b89c9e9
Autor:
Jennifer B. Permuth, Ashley Clark Daly, Daniel Jeong, Jung W. Choi, Miles E. Cameron, Dung‐Tsa Chen, Jamie K. Teer, Tracey E. Barnett, Jiannong Li, Benjamin D. Powers, Nagalakshmi B. Kumar, Thomas J. George, Karla N. Ali, Tri Huynh, Shraddha Vyas, Clement K. Gwede, Vani N. Simmons, Pamela J. Hodul, Estrella M. Carballido, Andrew R. Judge, Jason B. Fleming, Nipun Merchant, Jose G. Trevino
Publikováno v:
Cancer Medicine, Vol 8, Iss 6, Pp 3314-3324 (2019)
Abstract Pancreatic cancer (PC) is characterized by racial/ethnic disparities and the debilitating muscle‐wasting condition, cancer cachexia. Florida ranks second in the number of PC deaths and has a large and understudied minority population. We e
Externí odkaz:
https://doaj.org/article/4f5fe1ef9f3f497e9b3028594501715a