Zobrazeno 1 - 10
of 370
pro vyhledávání: '"Jiannis Ragoussis"'
Autor:
Claude Bhérer, Robert Eveleigh, Katerina Trajanoska, Janick St-Cyr, Antoine Paccard, Praveen Nadukkalam Ravindran, Elizabeth Caron, Nimara Bader Asbah, Peyton McClelland, Clare Wei, Iris Baumgartner, Marc Schindewolf, Yvonne Döring, Danielle Perley, François Lefebvre, Pierre Lepage, Mathieu Bourgey, Guillaume Bourque, Jiannis Ragoussis, Vincent Mooser, Daniel Taliun
Publikováno v:
npj Genomic Medicine, Vol 9, Iss 1, Pp 1-12 (2024)
Abstract Whole genome sequencing (WGS) at high-depth (30X) allows the accurate discovery of variants in the coding and non-coding DNA regions and helps elucidate the genetic underpinnings of human health and diseases. Yet, due to the prohibitive cost
Externí odkaz:
https://doaj.org/article/2b9f92fd459444789439a779da350076
Autor:
Julian Daniel Sunday Willett, Annie Gravel, Isabelle Dubuc, Leslie Gudimard, Ana Claudia dos Santos Pereira Andrade, Émile Lacasse, Paul Fortin, Ju-Ling Liu, Jose Avila Cervantes, Jose Hector Galvez, Haig Hugo Vrej Djambazian, Melissa Zwaig, Anne-Marie Roy, Sally Lee, Shu-Huang Chen, Jiannis Ragoussis, Louis Flamand
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-13 (2024)
Abstract The persistence of SARS-CoV-2 despite the development of vaccines and a degree of herd immunity is partly due to viral evolution reducing vaccine and treatment efficacy. Serial infections of wild-type (WT) SARS-CoV-2 in Balb/c mice yield mou
Externí odkaz:
https://doaj.org/article/7e05d290e45d4f32a383ce6ae1b567f7
Autor:
Gabriela Ulmo‐Diaz, Augustin Engman, William O. McLarney, Carlos A. Lasso Alcalá, Dean Hendrickson, Etienne Bezault, Eric Feunteun, Fernando L. Prats‐Léon, Jean Wiener, Robert Maxwell, Ryan S. Mohammed, Thomas J. Kwak, José Benchetrit, Bérénice Bougas, Charles Babin, Eric Normandeau, Haig H. V. Djambazian, Shu‐Huang Chen, Sarah J. Reiling, Jiannis Ragoussis, Louis Bernatchez
Publikováno v:
Evolutionary Applications, Vol 16, Iss 12, Pp 1872-1888 (2023)
Abstract The American eel (Anguilla rostrata) has long been regarded as a panmictic fish and has been confirmed as such in the northern part of its range. In this paper, we tested for the first time whether panmixia extends to the tropical range of t
Externí odkaz:
https://doaj.org/article/3058df059c524870bce7444f8d28b071
Autor:
Elena Kuzmin, Toby M. Baker, Tom Lesluyes, Jean Monlong, Kento T. Abe, Paula P. Coelho, Michael Schwartz, Joseph Del Corpo, Dongmei Zou, Genevieve Morin, Alain Pacis, Yang Yang, Constanza Martinez, Jarrett Barber, Hellen Kuasne, Rui Li, Mathieu Bourgey, Anne-Marie Fortier, Peter G. Davison, Atilla Omeroglu, Marie-Christine Guiot, Quaid Morris, Claudia L. Kleinman, Sidong Huang, Anne-Claude Gingras, Jiannis Ragoussis, Guillaume Bourque, Peter Van Loo, Morag Park
Publikováno v:
Cell Reports, Vol 43, Iss 4, Pp 113988- (2024)
Summary: The basal breast cancer subtype is enriched for triple-negative breast cancer (TNBC) and displays consistent large chromosomal deletions. Here, we characterize evolution and maintenance of chromosome 4p (chr4p) loss in basal breast cancer. A
Externí odkaz:
https://doaj.org/article/037f03f6925f4a5d977165ac992225f6
Autor:
Konstantinos Rouskas, Efthymia A. Katsareli, Charalampia Amerikanou, Alexandros C. Dimopoulos, Stavros Glentis, Alexandra Kalantzi, Anargyros Skoulakis, Nikolaos Panousis, Halit Ongen, Deborah Bielser, Alexandra Planchon, Luciana Romano, Vaggelis Harokopos, Martin Reczko, Panagiotis Moulos, Ioannis Griniatsos, Theodoros Diamantis, Emmanouil T. Dermitzakis, Jiannis Ragoussis, George Dedoussis, Antigone S. Dimas
Publikováno v:
BMC Genomics, Vol 24, Iss 1, Pp 1-17 (2023)
Abstract Background Expression quantitative trait loci (eQTL) studies provide insights into regulatory mechanisms underlying disease risk. Expanding studies of gene regulation to underexplored populations and to medically relevant tissues offers pote
Externí odkaz:
https://doaj.org/article/838d0c2e8e08407b91ad6f33fb6cc010
Autor:
Felicia Lazure, Rick Farouni, Korin Sahinyan, Darren M. Blackburn, Aldo Hernández-Corchado, Gabrielle Perron, Tianyuan Lu, Adrien Osakwe, Jiannis Ragoussis, Colin Crist, Theodore J. Perkins, Arezu Jahani-Asl, Hamed S. Najafabadi, Vahab D. Soleimani
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Aging leads to significant alteration in the gene expression of muscle stem cells. In vivo exposure of muscle stem cells from aged mice to a young niche environment restores the expression of a significant portion of age-altered genes in mice.
Externí odkaz:
https://doaj.org/article/e5288f7ec0dd4f6f85473190f3773765
Autor:
Melissa Zwaig, Audrey Baguette, Bo Hu, Michael Johnston, Hussein Lakkis, Emily M. Nakada, Damien Faury, Nikoleta Juretic, Benjamin Ellezam, Alexandre G. Weil, Jason Karamchandani, Jacek Majewski, Mathieu Blanchette, Michael D. Taylor, Marco Gallo, Claudia L. Kleinman, Nada Jabado, Jiannis Ragoussis
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-13 (2022)
Abstract Background Juvenile Pilocytic Astrocytomas (JPAs) are one of the most common pediatric brain tumors, and they are driven by aberrant activation of the mitogen-activated protein kinase (MAPK) signaling pathway. RAF-fusions are the most common
Externí odkaz:
https://doaj.org/article/4381905f37b94a1eb20515d76b4091cd
Autor:
Melissa Zwaig, Michael J. Johnston, John J.Y. Lee, Hamza Farooq, Marco Gallo, Nada Jabado, Michael D. Taylor, Jiannis Ragoussis
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionMedulloblastoma is the most common type of malignant pediatric brain tumor with group 4 medulloblastomas (G4 MBs) accounting for 40% of cases. However, the molecular mechanisms that underlie this subgroup are still poorly understood. Poin
Externí odkaz:
https://doaj.org/article/2df0625719f94299998677fbbdfe3ef2
Autor:
Samer Girgis, Zaikun Xu, Spyros Oikonomopoulos, Alla D. Fedorova, Egor P. Tchesnokov, Calvin J. Gordon, T. Martin Schmeing, Matthias Götte, Nahum Sonenberg, Pavel V. Baranov, Jiannis Ragoussis, Tom C. Hobman, Jerry Pelletier
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-12 (2022)
Genomes from defective interfering (DI) particles following serial passaging of SARS-CoV-2 reveal a fusion protein that attenuates viral replication. Synthetic, recombinant DI genomes are designed to interfere with SARS-CoV-2 replication.
Externí odkaz:
https://doaj.org/article/5e493b54c37c47c3a8ea41d5c87f53e3
Autor:
Germano Sollazzo, Georgia Gouvi, Katerina Nikolouli, Roswitha A Aumann, Haig Djambazian, Mark A Whitehead, Pierre Berube, Shu-Huang Chen, George Tsiamis, Alistair C Darby, Jiannis Ragoussis, Marc F Schetelig, Kostas Bourtzis
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 13, Iss 6 (2023)
AbstractGenetic sexing strains (GSS) are an important tool in support of sterile insect technique (SIT) applications against insect pests and disease vectors. The yet unknown temperature-sensitive lethaltslwhite pupaewpCeratitis capitatatsltslwpZwtsl
Externí odkaz:
https://doaj.org/article/8451d14ddc0f4742b7b5d6d56d06797f