Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Jiann Kae Luo"'
Autor:
András Guttman, Jiann-Kae Luo, Zoltan Szabo, Marcell Olajos, Gordon Freckleton, Shiva Pourkaveh, Toni Duffy, Ted Haxo, Michael Kimzey, David A. Michels, Eoin Cosgrave, Wenbo Wang, Preeti Sejwal, Jun Qian, Pui-King Leung, Jonathan van Dyck, Kai Gao, Jo Wegstein, Catherine Lancaster, Samnang Tep, Peng Feng, Melissa Schwartz, Aled Jones, Ronald L. Kowle, Apolka Domokos, Csaba Váradi, Zoran Sosic, SungAe Suhr Park, Kelsey Catherine Dent, Ákos Szekrényes
Publikováno v:
ELECTROPHORESIS. 39:998-1005
In the first part of this publication, the results from an international study evaluating the precision (i.e., repeatability and reproducibility) of N-glycosylation analysis using capillary electrophoresis of APTS-labeled N-glycans were presented. Th
Autor:
Erica Pyles, Jingtai Cao, Nicholas J. Papadopoulos, Ali Amirkhosravi, George D. Yancopoulos, Françoise Bono, John L. Francis, Todd Meyer, Carmelo Romano, Nathalie Delesque, Yang Liu, Tammy T. Huang, Meredith Glinka, Pierre Savi, Terra Potocky, Douglas MacDonald, Jiann-Kae Luo, Stanley J. Wiegand, Neil Stahl, Joel H. Martin, Ashique Rafique, Kathir K. Muthusamy
Publikováno v:
Angiogenesis
Anti-vascular endothelial growth factor (VEGF) therapies have improved clinical outcomes for patients with cancers and retinal vascular diseases. Three anti-VEGF agents, pegaptanib, ranibizumab, and aflibercept, are approved for ophthalmic indication
Autor:
Jo Wegstein, Preeti Sejwal, François de l’Escaille, Jonathan van Dyck, Ákos Szekrényes, András Guttman, Anastasiya Manuilov, Kai Gao, Gordon Freckleton, Wenbo Wang, David A. Michels, Marcia Santos, Clarence Lew, Zoltan Szabo, Ted Haxo, Michael Kimzey, Peng Feng, Jean Bernard Falmagne, Samnang Tep, Pui King Leung, Aled Jones, Jiann Kae Luo, Yingmei Gu, Csaba Váradi, Melissa Hamm, Thomas Niedringhaus, Melissa Schwartz, Zoran Sosic, Sung Ae Suhr Park, Marcell Olajos, Shiva Pourkaveh
Publikováno v:
mAbs
An international team that included 20 independent laboratories from biopharmaceutical companies, universities, analytical contract laboratories and national authorities in the United States, Europe and Asia was formed to evaluate the reproducibility
Publikováno v:
The Journal of Immunology. 181:6467-6472
Hepatitis B virus (HBV) causes both acute and chronic infection of the human liver and is associated with the development of liver cirrhosis and hepatocellular carcinoma. UBP43 (USP18) is known as an ISG15-deconjugating enzyme and an inhibitor of typ
Autor:
Xiang-Lei Yang, Eleni Tzima, Mili Kapoor, Christopher A. Myers, Rajesh Belani, Jiann Kae Luo, Paul Schimmel, Quansheng Zhou, Dong-Er Zhang, Francella J. Otero, Jianming Liu, Alison Bates
Publikováno v:
Journal of Biological Chemistry. 283:2070-2077
In mammalian cells, specific aminoacyl-transfer RNA (tRNA) synthetases have cytokine functions that require interactions with partners outside of the translation apparatus. Little is known about these interactions and how they facilitate expanded fun
Autor:
Keun Il Kim, K.G. Suresh Kumar, Serge Y. Fuchs, Oxana A. Malakhova, Dong-Er Zhang, Weiguo Zou, Jiann-Kae Luo, Ke Shuai
Publikováno v:
The EMBO Journal. 25:2358-2367
Interferons (IFNs) regulate diverse cellular functions through activation of the Janus kinase–signal transducer and activator of transcription (JAK–STAT) pathway. Lack of Ubp43, an IFN-inducible ISG15 deconjugating enzyme, leads to IFN hypersensi
Autor:
Ming Yan, Ruibao Ren, Jiann-Kae Luo, Dong-Er Zhang, Kenneth J. Ritchie, Ikuya Sakai, Kasuto Takeuchi
Publikováno v:
Blood. 110(1)
Interferon (IFN) signaling induces the expression of interferon-responsive genes and leads to the activation of pathways that are involved in the innate immune response. Ubp43 is an ISG15-specific isopeptidase, the expression of which is activated by
Publikováno v:
Blood cells, moleculesdiseases. 36(3)
Interferon-stimulated gene 15 (ISG15) is a ubiquitin-like modifier that forms conjugates with target protein substrates. As its name suggests, its expression and conjugation to other proteins are highly regulated by interferon (IFN). It was recently
Autor:
Juan Carlos de la Torre, Keun Il Kim, Oxana A. Malakhova, Jiann-Kae Luo, Mei-Feng Shen, Weiguo Zou, Ming Yan, Dong-Er Zhang
Publikováno v:
Molecular and cellular biology. 26(2)
The expression of ubiquitin-like modifier ISG15 and its conjugation to target proteins are highly induced by interferon (IFN) stimulation and during viral and bacterial infections. However, the biological significance of this modification has not bee
Autor:
Ernest C. Borden, Barbara S. Jacobs, Herbert W. Virgin, Nadia V. Giannakopoulos, Deborah J. Lenschow, Weiguo Zou, Jun Li, Dong-Er Zhang, Jiann Kae Luo, Vladimir Papov
Publikováno v:
Biochemical and biophysical research communications. 336(2)
Though the interferon-inducible protein ISG15 was one of the first ubiquitin-like modifiers to be discovered, much remains unknown about the identity of proteins conjugated to ISG15 or the biologic consequences of modification. To gain a better under