Zobrazeno 1 - 10
of 224
pro vyhledávání: '"Jianming Pei"'
Publikováno v:
PeerJ, Vol 12, p e17333 (2024)
Acute heart attack is the primary cause of cardiovascular-related death worldwide. A common treatment is reperfusion of ischemic tissue, which can cause irreversible damage to the myocardium. The number of mitochondria in cardiomyocytes is large, whi
Externí odkaz:
https://doaj.org/article/07c4bc17b7034aafbd3c3648e9cb861c
Autor:
Rui Shi, Zhenhua Liu, Huan Yue, Man Li, Simin Liu, Dema De, Runjing Li, Yunan Chen, Shuli Cheng, Xiaoming Gu, Min Jia, Jun Li, Juan Li, Shumiao Zhang, Na Feng, Rong Fan, Feng Fu, Yali Liu, Mingge Ding, Jianming Pei
Publikováno v:
Cellular & Molecular Biology Letters, Vol 29, Iss 1, Pp 1-24 (2024)
Abstract Introduction There is a high morbidity and mortality rate in mechanical trauma (MT)-induced hepatic injury. Currently, the molecular mechanisms underlying liver MT are largely unclear. Exploring the underlying mechanisms and developing safe
Externí odkaz:
https://doaj.org/article/a0d1433dd8a745c18614f8d9003f1e57
Autor:
Yavuz Sahin, Jianming Pei, Don A. Baldwin, Nashwa Mansoor, Lori Koslosky, Peter Abdelmessieh, Y. Lynn Wang, Reza Nejati, Joseph. R. Testa
Publikováno v:
Leukemia Research Reports, Vol 21, Iss , Pp 100465- (2024)
Acute myeloid leukemia (AML) is a heterogeneous hematological malignancy associated with various combinations of gene mutations, epigenetic abnormalities, and chromosome rearrangement-related gene fusions. Despite the significant degree of heterogene
Externí odkaz:
https://doaj.org/article/f0c3cc23a9b1481eaa5a4ec667934ac3
Autor:
Yavuz Sahin, Y. Lynn Wang, Jianming Pei, Nashwa Mansoor, Michael Styler, Joseph R. Testa, Reza Nejati
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 1, p 305 (2023)
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare hematologic malignancy with an aggressive clinical course and poor prognosis. The genetic abnormalities in BPDCN are heterogeneous; therefore, its molecular pathogenesis and the prognosti
Externí odkaz:
https://doaj.org/article/a79605f3e0f244698ce199c1312c6701
Autor:
Reza Nejati, Ryan Neumann-Domer, Zemin Liu, Lori Koslosky, Erin Neumann-Domer, Jianming Pei, Y. Lynn Wang, Joseph R. Testa
Publikováno v:
Leukemia Research Reports, Vol 20, Iss , Pp 100387- (2023)
We describe genomic findings in an AML case with isochromosome 7p, i(7)(p10), in which SNP array analysis uncovered an additional 7.07-Mb 20q deletion not detected by karyotyping. Several AML cases with i(7)(p10) as an isolated cytogenetic finding ha
Externí odkaz:
https://doaj.org/article/983bc9414f3c41d99a042aecf066b7b8
Autor:
Mingge Ding, Rui Shi, Shuli Cheng, Man Li, Dema De, Chaoyang Liu, Xiaoming Gu, Juan Li, Shumiao Zhang, Min Jia, Rong Fan, Jianming Pei, Feng Fu
Publikováno v:
Redox Biology, Vol 52, Iss , Pp 102315- (2022)
Externí odkaz:
https://doaj.org/article/22c750b2af3b4b8880130e3b69ed1a5a
Autor:
Mingge Ding, Rui Shi, Shuli Cheng, Man Li, Dema De, Chaoyang Liu, Xiaoming Gu, Juan Li, Shumiao Zhang, Min Jia, Rong Fan, Jianming Pei, Feng Fu
Publikováno v:
Redox Biology, Vol 52, Iss , Pp 102311- (2022)
Imbalanced mitochondrial dynamics including inhibited mitochondrial fusion is associated with cardiac dysfunction as well as tumorigenesis. This study sought to explore the effects of promoting mitochondrial fusion on doxorubicin(Dox)-induced cardiot
Externí odkaz:
https://doaj.org/article/301d70919b3043189ccf31b43c41d36b
Autor:
Pin Lu, Shengchun Wang, Carrie A. Franzen, Girish Venkataraman, Rebecca McClure, Lei Li, Wenjun Wu, Nifang Niu, Madina Sukhanova, Jianming Pei, Donald A. Baldwin, Reza Nejati, Mariusz A. Wasik, Nadia Khan, Yifan Tu, Juehua Gao, Yihua Chen, Shuo Ma, Richard A. Larson, Y. Lynn Wang
Publikováno v:
Blood Cancer Journal, Vol 11, Iss 2, Pp 1-14 (2021)
Abstract Ibrutinib inhibits Bruton tyrosine kinase while venetoclax is a specific inhibitor of the anti-apoptotic protein BCL2. Both drugs are highly effective as monotherapy against chronic lymphocytic leukemia (CLL), and clinical trials using the c
Externí odkaz:
https://doaj.org/article/849baea9e9ce42e89fc77c87bc31fab7
Autor:
Chaoyang Liu, Yuehu Han, Xiaoming Gu, Man Li, Yanyan Du, Na Feng, Juan Li, Shumiao Zhang, Leonid N. Maslov, Guoen Wang, Jianming Pei, Feng Fu, Mingge Ding
Publikováno v:
Redox Biology, Vol 46, Iss , Pp 102098- (2021)
Diabetes disrupts mitochondrial function and often results in diabetic cardiomyopathy (DCM). Paeonol is a bioactive compound that has been reported to have pharmacological potential for cardiac and mitochondrial protection. This study aims to explore
Externí odkaz:
https://doaj.org/article/8b0c86eabb9a4c9ca7f586afc906ac27
Autor:
Tim N. Beck, Yanis A. Boumber, Charu Aggarwal, Jianming Pei, Catherine Thrash-Bingham, Patricia Fittipaldi, Ramillya Vlasenkova, Chandra Rao, Hossein Borghaei, Massimo Cristofanilli, Ranee Mehra, Ilya Serebriiskii, R. Katherine Alpaugh
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-13 (2019)
Abstract Background Circulating tumor cells (CTC) and plasma cell-free RNA (cfRNA) can serve as biomarkers for prognosis and treatment response in lung cancer. One barrier to the selected or routine use of CTCs and plasma cfRNA in precision oncology
Externí odkaz:
https://doaj.org/article/c82abf3eb8ec43f98450bacf98f29960