Zobrazeno 1 - 10
of 635
pro vyhledávání: '"Jianming, Wu"'
Autor:
Xiaogang Zhou, Jing Wang, Lu Yu, Gan Qiao, Dalian Qin, Betty Yuen-Kwan Law, Fang Ren, Jianming Wu, Anguo Wu
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 8, Pp 3327-3361 (2024)
Mitophagy, essential for mitochondrial health, selectively degrades damaged mitochondria. It is intricately linked to the cGAS–STING pathway, which is crucial for innate immunity. This pathway responds to mitochondrial DNA and is associated with ce
Externí odkaz:
https://doaj.org/article/1471e72ae72c4e8f9f45471e7ca494cb
Autor:
Jiahan Zhou, Shengli Wan, Yuesong Wu, Haiyang Hu, Yang Liu, Zuyue Liao, Mengyao Xu, Jianming Wu, Qingze Fan
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 177, Iss , Pp 117102- (2024)
Paclitaxel (PTX) is a first-line drug for the treatment of lung cancer, but its targeting and therapeutic effect are unsatisfactory. Herein, lung cancer cell (A549) membrane biomimetic PTX-loaded poly (lactic-co-glycolic acid) (PLGA) nanoparticles (A
Externí odkaz:
https://doaj.org/article/78474693521a4204af06ac533c9f0279
Autor:
Yunfang Li, Jianming Wu
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
CD177 plays an important role in the proliferation and differentiation of myeloid lineage cells including neutrophils, myelocytes, promyelocytes, megakaryocytes, and early erythroblasts in bone marrow. CD177 deficiency is a common phenotype in humans
Externí odkaz:
https://doaj.org/article/991d525a026c44adbba268ee2233eaef
Autor:
Jeffrey S Miller, Martin Felices, Shee Kwan Phung, Anders W Matson, Sam Wang, Ryan R Friess, Bruce Walcheck, Kate J Dixon, Jianming Wu, Rob Hullsiek, Anders J Lindstedt, Tanya S Freedman, Emily N Truckenbrod
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 7 (2024)
Background Natural killer (NK) cells are being extensively studied as a cell therapy for cancer. These cells are activated by recognition of ligands and antigens on tumor cells. Cytokine therapies, such as IL-15, are also broadly used to stimulate en
Externí odkaz:
https://doaj.org/article/5e8cbf8ebe014603ad1dd5faf7ed4016
Autor:
Kate J. Dixon, Kristin M. Snyder, Melissa Khaw, Robert Hullsiek, Zachary B. Davis, Anders W. Matson, Soheila Shirinbak, Bryan Hancock, Ryan Bjordahl, Martin Hosking, Jeffrey S. Miller, Bahram Valamehr, Jianming Wu, Bruce Walcheck
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionNK cells can mediate tumor cell killing by natural cytotoxicity and by antibody-dependent cell-mediated cytotoxicity (ADCC), an anti-tumor mechanism mediated through the IgG Fc receptor CD16A (FcγRIIIA). CD16A polymorphisms conferring in
Externí odkaz:
https://doaj.org/article/25f0bc6b630e4c64ae1fcc8be73d5e42
Autor:
Yong Tang, Jing Wei, Xiao-Fang Wang, Tao Long, Xiaohong Xiang, Liqun Qu, Xingxia Wang, Chonglin Yu, Xingli Xiao, Xueyuan Hu, Jing Zeng, Qin Xu, Anguo Wu, Jianming Wu, Dalian Qin, Xiaogang Zhou, Betty Yuen-Kwan Law
Publikováno v:
Neural Regeneration Research, Vol 19, Iss 11, Pp 2467-2479 (2024)
Amyloid-beta-induced neuronal cell death contributes to cognitive decline in Alzheimer’s disease. Citri Reticulatae Semen has diverse beneficial effects on neurodegenerative diseases, including Parkinson’s and Huntington’s diseases, however, th
Externí odkaz:
https://doaj.org/article/47fd4ae8f9814548af6e3edf2a0cae7a
Autor:
Weixin Wang, Rui Gao, Lin Zhang, Zhongchao Wang, Jiahui Sun, Lei Luo, Min Pan, Miaofang Hong, Jianming Wu, Qibing Mei, Ke Tong, Yini Wang, Lingyan Qiao, Fei Tong
Publikováno v:
Pharmaceutical Science Advances, Vol 2, Iss , Pp 100044- (2024)
Acute kidney injury (AKI) is characterized by a rapid loss of renal metabolic function and a high mortality rate. Although significant progress has been made in developing targeted drugs for AKI treatment, issues such as inadequate antioxidant effect
Externí odkaz:
https://doaj.org/article/93e7aa8456754fc5ac411f8712b5e215
Autor:
Qianhui Zhang, Miao Huang, Elizabeth Rosalind Thomas, Lu Wang, Jia Liu, Xiang Li, Jiesi Luo, Wenjun Zou, Jianming Wu
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Primary immune thrombocytopenia (ITP) is an acquired autoimmune disorder characterized by the destruction of platelets. Although it was long believed that the critical role of autoantibodies in platelet destruction, primarily through the Fc-dependent
Externí odkaz:
https://doaj.org/article/2dd2e676c0764389a629f2cf99372201
Autor:
Chengyang Ni, Liang Yue, Mei Ran, Long Wang, Feihong Huang, Shuo Yang, Jia Lai, Nan Jiang, Xinwu Huang, Dalian Qin, Hua Li, Jie Zhou, Jing Zeng, Anguo Wu, Jianming Wu
Publikováno v:
Heliyon, Vol 10, Iss 11, Pp e32230- (2024)
Colon cancer is a common gastrointestinal malignancy that ranks third in incidence among gastrointestinal cancers. Therefore, screening bioactive compounds for treatment of colon cancer is urgently needed. Sanguisorba officinalis L. (SO) has been dem
Externí odkaz:
https://doaj.org/article/b2733dec94ef4d6092bb6d62bb8e0076
Autor:
Ling Zhou, Chengyang Ni, Ruixue Liao, Xiaoqin Tang, Taian Yi, Mei Ran, Miao Huang, Rui Liao, Xiaogang Zhou, Dalian Qin, Long Wang, Feihong Huang, Xiang Xie, Ying Wan, Jiesi Luo, Yiwei Wang, Jianming Wu
Publikováno v:
eLife, Vol 13 (2024)
Thrombocytopenia caused by long-term radiotherapy and chemotherapy exists in cancer treatment. Previous research demonstrates that 5-Hydroxtrayptamine (5-HT) and its receptors induce the formation of megakaryocytes (MKs) and platelets. However, the r
Externí odkaz:
https://doaj.org/article/159287c007c74b5fa9a5d514f8ecf46c