Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Jianlei Hao"'
Autor:
Mingyue Zhang, Dehai Li, Jing Zhu, Xue Xia, Hua Zhang, Jie Wu, Shengli Wang, Anyi Deng, Qiong Wen, Jingyi Tan, Jianlei Hao, Jun Jiang, Xiucong Bao, Guodong Sun, Jiajing Lu, Quanli Yang, Hengwen Yang, Guangchao Cao, Zhinan Yin, Qian Wang
Publikováno v:
Cell Death and Disease, Vol 15, Iss 7, Pp 1-12 (2024)
Abstract IL-17+ γδ T cells (γδ T17) are kick-starters of inflammation due to their strict immunosurveillance of xenobiotics or cellular damages and rapid response to pro-inflammatory stimulators. IL-27 is a well-recognized pleiotropic immune regu
Externí odkaz:
https://doaj.org/article/d503a33bb31b4eb28b26b43608f60b36
Autor:
Lingfeng Yan, Jue Wang, Xin Cai, Yih‐Cherng Liou, Han‐Ming Shen, Jianlei Hao, Canhua Huang, Gaoxing Luo, Weifeng He
Publikováno v:
MedComm, Vol 5, Iss 8, Pp n/a-n/a (2024)
Abstract Macrophages are versatile immune cells with remarkable plasticity, enabling them to adapt to diverse tissue microenvironments and perform various functions. Traditionally categorized into classically activated (M1) and alternatively activate
Externí odkaz:
https://doaj.org/article/6feca251625a443bb964ce7a721bdba9
Autor:
Wengang Hu, Xiaorong Zhang, Zhongyang Liu, Jiacai Yang, Hao Sheng, Zhihui Liu, Cheng Chen, Ruoyu Shang, Yunxia Chen, Yifei Lu, Xiaohong Hu, Yong Huang, Wenjing Yin, Xin Cai, Dejiang Fan, Lingfeng Yan, Jianlei Hao, Gaoxing Luo, Weifeng He
Publikováno v:
iScience, Vol 27, Iss 4, Pp 109545- (2024)
Summary: Dysregulated macrophage polarization from pro-inflammatory M1 to anti-inflammatory M2 phenotypes underlies impaired cutaneous wound healing. This study reveals Vγ4+ γδ T cells spatiotemporally calibrate macrophage trajectories during skin
Externí odkaz:
https://doaj.org/article/b31fa587b2fc4dfd8d61a3feacb723d2
Autor:
Shengli Wang, Mingyue Zhang, Hongyan Sun, Tao Li, Jianlei Hao, Meixia Fang, Jie Dong, Hongbiao Xu
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2024)
Background: The TLC Domain Containing 1 (TLCD1) protein, a key regulator of phosphatidylethanolamine (PE) composition, is distributed across several cellular membranes, including mitochondrial plasma membranes. Existing research has revealed the impa
Externí odkaz:
https://doaj.org/article/1ab610e946b540a8b97db79d91203d95
Autor:
Qihui Liu, Quanli Yang, Zengfeng Wu, Yanfang Chen, Miaomiao Xu, Hua Zhang, Jiliang Zhao, Zonghua Liu, Zerong Guan, Jing Luo, Zhi-yong Li, Guodong Sun, Qiong Wen, Yan Xu, Zhenhua Li, Kebing Chen, Xiaosong Ben, Wanchun He, Xueshi Li, Zhinan Yin, Jianlei Hao, Ligong Lu
Publikováno v:
Cell Death and Disease, Vol 13, Iss 4, Pp 1-12 (2022)
Abstract Liver fibrosis represents a severe stage of liver damage, with hallmarks of inflammation, hepatic stellate cell activation, and extracellular matrix accumulation. Although previous studies demonstrated γδ T cells are involved in liver fibr
Externí odkaz:
https://doaj.org/article/4762719b2fb149fca74102adb0ea3e0e
Publikováno v:
Infectious Microbes & Diseases, Vol 3, Iss 3, Pp 142-148 (2021)
Abstract. Metabolic change is associated with cell activities, such as signal transduction, cell differentiation, and cell cycle. In the pathogenesis of autoimmune diseases, abnormal activation of T cells is often accompanied by changes in their meta
Externí odkaz:
https://doaj.org/article/ccde20f4f2d44721a85ed497601b6f4f
Autor:
Yi Hu, Dan Chen, Minjing Hong, Jing Liu, Yijia Li, Jianlei Hao, Ligong Lu, Zhinan Yin, Yangzhe Wu
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Hepatocellular carcinoma (HCC) is highly malignant and prone to metastasize due to the heterogeneous and immunosuppressive tumor microenvironment (TME). Programmed cell deaths (PCDs) including apoptosis, ferroptosis, and pyroptosis routinely occur in
Externí odkaz:
https://doaj.org/article/a4c4a59422d14242a60d6cfc2da351ce
Autor:
Juan Liang, Liang Fu, Man Li, Yuyuan Chen, Yi Wang, Yi Lin, Hailin Zhang, Yan Xu, Linxiu Qin, Juncai Liu, Weiyu Wang, Jianlei Hao, Shuyan Liu, Peize Zhang, Li Lin, Mohammed Alnaggar, Jie Zhou, Lin Zhou, Huixin Guo, Zhaoqin Wang, Lei Liu, Guofang Deng, Guoliang Zhang, Yangzhe Wu, Zhinan Yin
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The WHO’s “Global tuberculosis report 2020” lists tuberculosis (TB) as one of the leading causes of death globally. Existing anti-TB therapy strategies are far from adequate to meet the End TB Strategy goals set for 2035. Therefore, novel anti-
Externí odkaz:
https://doaj.org/article/b430075b459347ca8e1abd184ae6c34f
Autor:
Yixi Wang, Na Zhao, Xianwen Zhang, Zhenhua Li, Zheng Liang, Jinrong Yang, Xingyu Liu, Yangzhe Wu, Kebing Chen, Yunfei Gao, Zhinan Yin, Xuejia Lin, Haibo Zhou, Dongbo Tian, Yang Cao, Jianlei Hao
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
The butyrophilins (BTNs) represent a unique family of immunoglobulin. They were considered to be involved in milk lactation after their discovery in 1981. With the development of research, an increasing number of research revealed that BTNs play impo
Externí odkaz:
https://doaj.org/article/264835f6004246d6ac0184785bf629f1
Autor:
Qian Wang, Dehai Li, Jing Zhu, Mingyue Zhang, Hua Zhang, Guangchao Cao, Leqing Zhu, Qiping Shi, Jianlei Hao, Qiong Wen, Zonghua Liu, Hengwen Yang, Zhinan Yin
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Non-alcoholic fatty liver disease (NAFLD) is one of the main causes of cirrhosis and major risk factors for hepatocellular carcinoma and liver-related death. Despite substantial clinical and basic research, the pathogenesis of obesity-related NAFLD r
Externí odkaz:
https://doaj.org/article/6fa4c4b65dcb4f9cb8b40b5eb41312cb