Zobrazeno 1 - 10
of 128
pro vyhledávání: '"Jianjun Chang"'
Autor:
Adam M. Hamilton, Lisa Blackmer-Raynolds, Yaqing Li, Sean D. Kelly, Nardos Kebede, Anna E. Williams, Jianjun Chang, Sandra M. Garraway, Shanthi Srinivasan, Timothy R. Sampson
Publikováno v:
npj Biofilms and Microbiomes, Vol 10, Iss 1, Pp 1-12 (2024)
Abstract Spinal cord injury (SCI) results in numerous systemic dysfunctions, including intestinal dysmotility and enteric nervous system (ENS) atrophy. The ENS has capacity to recover following perturbation, yet intestinal pathologies persist. With e
Externí odkaz:
https://doaj.org/article/15c1690b33ae465794ceaf50c419c3b4
Autor:
Maria Elizabeth De Sousa Rodrigues, MacKenzie L. Bolen, Lisa Blackmer-Raynolds, Noah Schwartz, Jianjun Chang, Malú Gámez Tansey, Timothy Robert Sampson
Publikováno v:
Neurobiology of Disease, Vol 196, Iss , Pp 106511- (2024)
Emerging evidence indicates that high-fat, high carbohydrate diet (HFHC) impacts central pathological features of Alzheimer's disease (AD) across both human incidences and animal models. However, the mechanisms underlying this association are poorly
Externí odkaz:
https://doaj.org/article/1fbc33332fa7417c9cd36bb82e177ec7
Publikováno v:
Arabian Journal of Chemistry, Vol 17, Iss 3, Pp 105582- (2024)
Intervertebral disc (IVD) degeneration is an age-related disease affecting the elderly population worldwide. The disease is contributed by degeneration of the cartilage tissue in the vertebral column. The current study explores the possibility of exp
Externí odkaz:
https://doaj.org/article/0f0c20e16fab4f87a933b0d523bfdf76
Autor:
Haoyue Yang, Yiming Chen, Siddiq Ur Rahman, Yunpeng Wang, Silu Ni, Yuecai Jiang, Fang Zhu, Dengliang Li, Qihang Cao, Jianjun Chang, Ying Wen, Dekun Chen, Ma Wentao
Publikováno v:
PLoS ONE, Vol 19, Iss 5 (2024)
Externí odkaz:
https://doaj.org/article/157c501aa5da40f3a1d1dc1b5a788b1e
Publikováno v:
Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-9 (2023)
Abstract Background Acute lung injury is characterized by overwhelmingly elevated PAI-1 in both lung edema fluid and the circulating system. The role of increased PAI-1, encoded by Serpine1 gene, in the regeneration of injured lung epithelium has not
Externí odkaz:
https://doaj.org/article/013c1d4f56174a79b79d8bcf29d2b68d
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 18, Iss 1, Pp 1-9 (2023)
Abstract Background and Objective Carpal tunnel syndrome (CTS) is the most common type of median nerve entrapment neuropathy. This study aims to comparatively assess the effectiveness and clinical efficacy of modified transforaminal endoscopic minima
Externí odkaz:
https://doaj.org/article/159426f2d5e3456390ed84668a3d9e30
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
BackgroundCarpal Tunnel Syndrome (CTS) is one of the most common peripheral neuropathies. The typical symptoms are tingling and numbness in the median nerve distribution of the hand. Current treatment for CTS includes general conservative treatment a
Externí odkaz:
https://doaj.org/article/c161f7aa38484200a7dcaea9403c4589
Autor:
Kathryn P. MacPherson, Lori N. Eidson, Madelyn C. Houser, Blaine E. Weiss, Jenna L. Gollihue, Mary K. Herrick, Maria Elizabeth de Sousa Rodrigues, Lindsey Sniffen, Erica M. Weekman, Adam M. Hamilton, Sean D. Kelly, Danielle L. Oliver, Yuan Yang, Jianjun Chang, Timothy R. Sampson, Christopher M. Norris, Malú Gámez Tansey
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
Introduction: Increasing evidence indicates that neurodegenerative diseases, including Alzheimer’s disease (AD), are a product of gene-by-environment interplay. The immune system is a major contributor mediating these interactions. Signaling betwee
Externí odkaz:
https://doaj.org/article/3d009ff4b94a4ec88ead67237c2990e0
Autor:
Madelyn C. Houser, Oihane Uriarte Huarte, Rebecca L. Wallings, Cody E. Keating, Kathryn P. MacPherson, Mary K. Herrick, George T. Kannarkat, Sean D. Kelly, Jianjun Chang, Nicholas H. Varvel, Jessica E. Rexach, Malú Gámez Tansey
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
IntroductionProgranulin (PGRN) is a secreted glycoprotein, the expression of which is linked to several neurodegenerative diseases. Although its specific function is still unclear, several studies have linked it with lysosomal functions and immune sy
Externí odkaz:
https://doaj.org/article/4d8a321115ff4a7a8acb3699a6026cab
Autor:
Madelyn C. Houser, W. Michael Caudle, Jianjun Chang, George T. Kannarkat, Yuan Yang, Sean D. Kelly, Danielle Oliver, Valerie Joers, Kathleen M. Shannon, Ali Keshavarzian, Malú Gámez Tansey
Publikováno v:
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-23 (2021)
Abstract Background The etiology of sporadic Parkinson’s disease (PD) remains uncertain, but genetic, epidemiological, and physiological overlap between PD and inflammatory bowel disease suggests that gut inflammation could promote dysfunction of d
Externí odkaz:
https://doaj.org/article/8e618e46d41448b989d12a0fc10bd262