Zobrazeno 1 - 10
of 493
pro vyhledávání: '"Jianjie, Ma"'
Autor:
Samuel Speaks, Matthew I. McFadden, Ashley Zani, Abigail Solstad, Steve Leumi, Jack E. Roettger, Adam D. Kenney, Hannah Bone, Lizhi Zhang, Parker J. Denz, Adrian C. Eddy, Amal O. Amer, Richard T. Robinson, Chuanxi Cai, Jianjie Ma, Emily A. Hemann, Adriana Forero, Jacob S. Yount
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Influenza virus activates cellular inflammasome pathways, which can be both beneficial and detrimental to infection outcomes. Here, we investigate the function of the inflammasome-activated, pore-forming protein gasdermin D (GSDMD) during in
Externí odkaz:
https://doaj.org/article/1bdb4d643c5340eaab89b6eb41184ba9
Autor:
Xiao-Liang Wang, Xiangfei He, Tong Gao, Xinyu Zhou, Zobeida Cruz-Monserrate, Allan Tsung, Jianjie Ma, Chuanxi Cai
Publikováno v:
Translational Oncology, Vol 50, Iss , Pp 102118- (2024)
Pancreatic ductal adenocarcinoma (PDAC) poses a formidable challenge in oncology due to its limited treatment options and poor long-term survival rates. Our previous work identified MG53, a member of the tripartite motif family protein (TRIM72), as a
Externí odkaz:
https://doaj.org/article/428077f6371d45f0b6084e5b72312785
Publikováno v:
eLife, Vol 12 (2024)
Amyotrophic lateral sclerosis (ALS) is a fatal neuromuscular disorder characterized by progressive weakness of almost all skeletal muscles, whereas extraocular muscles (EOMs) are comparatively spared. While hindlimb and diaphragm muscles of end-stage
Externí odkaz:
https://doaj.org/article/34994457f66f41a3864668d6d805b3e5
Autor:
Hong Niu, Haichang Li, Ya Guan, Xin Zhou, Zhongguang Li, Serana Li Zhao, Peng Chen, Tao Tan, Hua Zhu, Valerie Bergdall, Xuehong Xu, Jianjie Ma, Jianjun Guan
Publikováno v:
Bioactive Materials, Vol 18, Iss , Pp 104-115 (2022)
MG53 is an essential component of the cell membrane repair machinery, participating in the healing of dermal wounds. Here we develop a novel delivery system using recombinant human MG53 (rhMG53) protein and a reactive oxygen species (ROS)-scavenging
Externí odkaz:
https://doaj.org/article/7d546b891bd940b489b16c3544b2d6d2
Autor:
Xinyu Zhou, Ju Hwan Cho, Jianxun Yi, Kyounghan Choi, Ki Ho Park, Hua Zhu, Chuanxi Cai, Erin Haggard, Jingsong Zhou, Jae-Kyun Ko, Jianjie Ma
Publikováno v:
STAR Protocols, Vol 4, Iss 1, Pp 101871- (2023)
Summary: Evaluation of autophagy flux could be challenging for muscle fibers due to the baseline expression of mCherry-EGFP-LC3 along the Z-line. We established a protocol to overcome this difficulty. We overexpress mChery-EGFP-LC3 in the FDB muscle
Externí odkaz:
https://doaj.org/article/1cb00a5ad4d34429be28f5b4df5114e4
Autor:
Tao Dong, Barasa, Leonard, Xin Yu, Wenlu Ouyang, Liujiazi Shao, Chao Quan, Su He Wang, Jifeng Zhang, Salmon, Morgan, Tsung, Allan, Alam, Hasan B., Jianjie Ma, Thompson, Paul R., Yongqing Li
Publikováno v:
International Journal of Biological Sciences; 2024, Vol. 20 Issue 13, p5043-5055, 13p
Autor:
Haichang Li, Pei-Hui Lin, Pranav Gupta, Xiangguang Li, Serena Li Zhao, Xinyu Zhou, Zhongguang Li, Shengcai Wei, Li Xu, Renzhi Han, Jing Lu, Tao Tan, Dong-Hua Yang, Zhe-Sheng Chen, Timothy M. Pawlik, Robert E. Merritt, Jianjie Ma
Publikováno v:
Molecular Cancer, Vol 20, Iss 1, Pp 1-15 (2021)
Abstract Background Cancer cells develop resistance to chemotherapeutic intervention by excessive formation of stress granules (SGs), which are modulated by an oncogenic protein G3BP2. Selective control of G3BP2/SG signaling is a potential means to t
Externí odkaz:
https://doaj.org/article/927f7bde79de4345b15b1de3d3bbb033
Autor:
Fangxia Guan, Tuanjie Huang, Xinxin Wang, Qu Xing, Kristyn Gumpper, Peng Li, Jishi Song, Tao Tan, Greta Luyuan Yang, Xingxing Zang, Jiewen Zhang, Yuming Wang, Yunlei Yang, Yashi Liu, Yanting Zhang, Bo Yang, Jianjie Ma, Shanshan Ma
Publikováno v:
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-4 (2021)
Externí odkaz:
https://doaj.org/article/e21ccc4f4ee1417cbb93617b2d3c4aad
Autor:
Haichang Li, Zhongguang Li, Xiuchun Li, Chuanxi Cai, Serena Li Zhao, Robert E. Merritt, Xinyu Zhou, Tao Tan, Valerie Bergdall, Jianjie Ma
Publikováno v:
Cells, Vol 12, Iss 14, p 1915 (2023)
Sulfur mustard (SM) and nitrogen mustard (NM) are vesicant agents that cause skin injury and blistering through complicated cellular events, involving DNA damage, free radical formation, and lipid peroxidation. The development of therapeutic approach
Externí odkaz:
https://doaj.org/article/9baabc4c99314d48a190c0eae4c53a4d
Publikováno v:
Cell & Bioscience, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Heart disease remains the leading cause of mortality globally, so further investigation is required to identify its underlying mechanisms and potential targets for treatment and prevention. Mitsugumin 53 (MG53), also known as TRIM72, is a TR
Externí odkaz:
https://doaj.org/article/2085b7e4e34f4b278e811d8ce4ec488a