Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Jianji, Zhang"'
Autor:
Ziping Niu, Chen Chen, Siyu Wang, Congcong Lu, Zhiyue Wu, Aiyuan Wang, Jing Mo, Jianji Zhang, Yanpu Han, Ye Yuan, Yingao Zhang, Yong Zang, Chaoran He, Xue Bai, Shanshan Tian, Guijin Zhai, Xudong Wu, Kai Zhang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Lysine lactylation (Kla) links metabolism and gene regulation and plays a key role in multiple biological processes. However, the regulatory mechanism and functional consequence of Kla remain to be explored. Here, we report that HBO1 functio
Externí odkaz:
https://doaj.org/article/d7a24dd19c6f46a4b218889f3153a2f2
Autor:
Yong Zang, Aiyuan Wang, Jianji Zhang, Mingxin Xia, Zixin Jiang, Bona Jia, Congcong Lu, Chen Chen, Siyu Wang, Yingao Zhang, Chen Wang, Xinyi Cao, Ziping Niu, Chaoran He, Xue Bai, Shanshan Tian, Guijin Zhai, Hailong Cao, Yupeng Chen, Kai Zhang
Publikováno v:
iScience, Vol 27, Iss 7, Pp 110188- (2024)
Summary: Hypoxia promotes tumorigenesis and lactate accumulation in esophageal squamous cell carcinoma (ESCC). Lactate can induce histone lysine lactylation (Kla, a recently identified histone marks) to regulate transcription. However, the functional
Externí odkaz:
https://doaj.org/article/3b2073a3417144adabe213716af3dd57
Publikováno v:
Cancer Medicine, Vol 12, Iss 14, Pp 15217-15228 (2023)
Abstract Objective The treatment of biliary tract (BTC) cancer remains relatively limited, especially in the setting of advanced BTC. Immune checkpoint inhibitors (ICIs) have shown some effects in a variety of solid tumors, but their efficacy and saf
Externí odkaz:
https://doaj.org/article/2cb525bb37d4482b83b9650a4cb3565d
Autor:
Hanyang Dong, Jianji Zhang, Hui Zhang, Yue Han, Congcong Lu, Chen Chen, Xiaoxia Tan, Siyu Wang, Xue Bai, Guijin Zhai, Shanshan Tian, Tao Zhang, Zhongyi Cheng, Enmin Li, Liyan Xu, Kai Zhang
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
The characterization of lysine lactylation (Kla) in prokaryotes remains unclear. Here, the authors identify the regulatory enzymes (YiaC as a lactylase and CobB as a delactylase) and functional network of Kla and reveal a Kla-mediated molecular mecha
Externí odkaz:
https://doaj.org/article/a46ddc4af4564ff0af2c9c10326496cf
Autor:
Zhengfeng Zhang, Lei Yang, Dazhen Wang, Yuli Ruan, Jianji Zhang, Lu Zhao, Liu Yang, Changjie Lou
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 15 (2023)
Objective: To investigate the efficacy and safety differences between the cisplatin + paclitaxel (TP) and cisplatin + fluorouracil (PF) regimens in combination with or without immune checkpoint inhibitors (ICIs) in advanced esophageal squamous cell c
Externí odkaz:
https://doaj.org/article/a01cf94851bd417fbde8b45dfaaf78c7
Autor:
Ranran Liu, Yue Han, Zhiyue Wu, Jianji Zhang, Yong Zang, Lijin Shen, Shanshan Tian, Kai Zhang
Publikováno v:
Separations, Vol 9, Iss 5, p 112 (2022)
Formaldehyde (FA) is a toxic compound that is considered to have a carcinogenic effect due to its damage to biological macromolecules. However, the influence of FA at the protein level remains to be explored. Here, we used LC-MS/MS to identify the di
Externí odkaz:
https://doaj.org/article/8b40abe865464d73b8210a457b94f9f1
Autor:
Xiaowei, Sun, Jianji, Zhang, Li, Zhao, Liang, Zhao Qiu, Li, Shi, Zhongtao, Gai, Chunhong, Duan
Publikováno v:
In International Journal of Pediatric Otorhinolaryngology October 2014 78(10):1567-1570
Autor:
Lu Wang, Bo Fu, Da-Yong Hou, Yulin Lv, Guang Yang, Cong Li, Jiachen Shen, Bin Kong, Libo Zheng, Yu Qiu, Honglei Wang, Chen Liu, Jianji Zhang, Li-Li Li, Hao Wang, Wanhai Xu
Stronger intrinsic Warburg effect and resistance to chemotherapy are the responses to high mortality of renal cell carcinoma (RCC). Pyruvate kinase M2 (PKM2) plays an important role in this process. Promoting PKM2 conversion from dimer to tetramer is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1aa2cfc5a4f3c150b6364e3f99e66bb0
https://doi.org/10.21203/rs.3.rs-1598044/v1
https://doi.org/10.21203/rs.3.rs-1598044/v1
Publikováno v:
Materials & Design, Vol 143, Iss, Pp 285-296 (2018)
Additive manufacturing is a promising technique for the production of bulk metallic glass (BMG) components without size limitations. However, the current additive manufacturing technique encounters the challenge of micro-cracking induced by huge ther
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1afeae83ae73c5ab4c150de8a16c7079
https://doi.org/10.1016/j.matdes.2018.01.061
https://doi.org/10.1016/j.matdes.2018.01.061
Publikováno v:
Intermetallics. 90:128-134
3D printing of crack-free bulk metallic glasses remains challenge due to the generation of huge thermal stress during the selective laser melting and their intrinsic brittleness. Herein, Zr55Cu30Ni5Al10 system was selected and 3D printed by selective
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d0ee35593391f8859f91c8a54a1b4816
https://doi.org/10.1016/j.intermet.2017.07.010
https://doi.org/10.1016/j.intermet.2017.07.010