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Akademický článek

Identification of pathogenic germline variants in a large Chinese lung cancer cohort by clinical sequencing

Autor: Zhe Yu, Zirui Zhang, Jun Liu, Xiaoying Wu, Xiaojun Fan, Jiaohui Pang, Hua Bao, Jiani Yin, Xue Wu, Yang Shao, Zhengcheng Liu, Fang Liu

Publikováno v: Molecular Oncology, Vol 18, Iss 5, Pp 1301-1315 (2024)

Genetic factors play significant roles in the tumorigenicity of lung cancer; however, there is lack of systematic and large‐scale characterization of pathogenic germline variants for lung cancer. In this study, germline variants in 146 preselected

Externí odkaz: https://doaj.org/article/cc870fc6d19c4c80aed2eabd54506f0e

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Akademický článek

Examining the Reliability of the Emotional Conflict Resolution and Adaptation Effects in the Emotional Conflict Task via Secondary Data Analysis, Systematic Review, and Meta-Analysis.

Autor: Jiani Yin¹, Yi Wang¹, Lipp, Ottmar V.¹, Mayo, Luke J.^2,3 luke.ney@qut.edu.au, Ney, Luke J.¹

Publikováno v: Journal of Experimental Psychology. General. May2024, Vol. 153 Issue 5, p1361-1373. 13p.

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Clinical validity assessment of genes frequently tested on intellectual disability/autism sequencing panels

Publikováno v: Genetics in Medicine
Genetics in Medicine, 2022, 24 (9), pp.1899-1908. ⟨10.1016/j.gim.2022.05.001⟩

International audience; Purpose: Neurodevelopmental disorders (NDDs), such as intellectual disability (ID) and autism spectrum disorder (ASD), exhibit genetic and phenotypic heterogeneity, making them difficult to differentiate without a molecular di

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b07ead00b13dfac939c5dc9322d918b8
https://doi.org/10.1016/j.gim.2022.05.001

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A phase 3, multicenter study to assess the 1-year safety and tolerability of a combination of olanzapine and samidorphan in patients with schizophrenia: Results from the ENLIGHTEN-2 long-term extension

Autor: Ying Jiang, Adam Simmons, Craig Hopkinson, David McDonnell, Vasudev Bhupathi, Bernard L. Silverman, Bei Yu, Jiani Yin, Christine Graham, Lauren DiPetrillo, René S. Kahn, Sergey Yagoda

Publikováno v: Schizophrenia Research. 232:45-53

Aim A combination of olanzapine and samidorphan (OLZ/SAM) is in development for the treatment of patients with schizophrenia or bipolar I disorder and is intended to provide the efficacy of olanzapine while mitigating olanzapine-associated weight gai

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6907f444d0129dbbe4fcbbf3da905356
https://doi.org/10.1016/j.schres.2021.04.009

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Combination of whole exome sequencing and animal modeling identifies TMPRSS9 as a candidate gene for autism spectrum disorder

Autor: Huifang Tao, Aniko Sabo, Matthew N. Bainbridge, Christian P. Schaaf, Abdallah Amawi, Jiani Yin, Rituraj Pal, Chun-An Chen, Huda Y. Zoghbi, Richard A. Gibbs

Publikováno v: Hum Mol Genet

Autism spectrum disorders are associated with some degree of developmental regression in up to 30% of all cases. Rarely, however, is the regression so extreme that a developmentally advanced young child would lose almost all ability to communicate an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4eb92f2c091a000abcb88fb63b870c55
https://doi.org/10.1093/hmg/ddz305

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Core Transcription Programs Controlling Injury-Induced Neurodegeneration of Retinal Ganglion Cells

SUMMARYNeurodegenerative diseases are characterized by neuronal death and regenerative failure. However, gene regulatory programs governing how initial neuronal injuries lead to neuronal death remain poorly understood. In adult mice, optic nerve crus

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::85d49e5c1742ce8c2cd133ca9ab029e5
https://doi.org/10.1101/2022.01.20.477004

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Detection of Fraud Statement Using Calculation Models M-Score and F-Score: Evidence from Chinese Companies Listed in the United States

Autor: Ruixuan Zhou, Jiani Yin, Yuanheng Feng, Chenlin Xu, Runhe Zhu

Publikováno v: Proceedings of the 2022 2nd International Conference on Economic Development and Business Culture (ICEDBC 2022) ISBN: 9789464630350

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a6d1167c3d0f1fb4de9f66e4d837a72c
https://doi.org/10.2991/978-94-6463-036-7_115

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Comprehensive genomic analysis of early and late-onset hepatocellular carcinoma

Autor: Yang Shao, Xin Chen, Jiaohui Pang, Yaru Zhang, Qiuxiang Ou, Jiani Yin, Xue Wu

Publikováno v: Journal of Clinical Oncology. 40:e16186-e16186

e16186 Background: Hepatocellular carcinoma (HCC) accounts for 90% of primary liver cancer and is a leading cause of cancer-related death worldwide. HCC is highly therapy-resistant, and biomarker-driven therapies are emerging as important treatment o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e497232c7d59d8d58573abdd0ebfb0dc
https://doi.org/10.1200/jco.2022.40.16_suppl.e16186

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A Bayesian Small Area Model with Dirichlet Processes on the Responses

Autor: Balgobin Nandram, Jiani Yin

Publikováno v: Statistics in Transition, Vol 21, Iss 3 (2020)

Typically survey data have responses with gaps, outliers and ties, and the distributions of the responses might be skewed. Usually, in small area estimation, predictive inference is done using a two-stage Bayesian model with normality at both levels

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad636828fab04bbde7d3d7dead0ab051
https://www.exeley.com/exeley/journals/statistics_in_transition/21/3/pdf/10.21307_stattrans-2020-041.pdf

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CHRNA7 copy number gains are enriched in adolescents with major depressive and anxiety disorders

Autor: Christian P. Schaaf, Janson White, Christopher M. Grochowski, Chadi A. Calarge, Jiani Yin, Ricardo Lozoya, Madelyn A. Gillentine

Publikováno v: Journal of Affective Disorders. 239:247-252

Objective Neuronal nicotinic acetylcholine receptors (nAChRs), specifically the α7 nAChR encoded by the gene CHRNA7, have been implicated in behavior regulation in animal models. In humans, copy number variants (CNVs) of CHRNA7 are found in a range

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f54098347749069e4cf14afcf9dbc5b8
https://doi.org/10.1016/j.jad.2018.07.017

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