Zobrazeno 1 - 10
of 145
pro vyhledávání: '"Jianhua Sui"'
Autor:
Wenhui Li, Fang Yang, Xueyuan Lyu, Linlin Zhao, Sijia Chen, Yulu Li, Yajing Yang, Huisi Liu, Jianhua Sui
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 8 (2024)
Background Tumor necrosis factor receptor superfamily 25 (TNFRSF25) is a T-cell co-stimulatory receptor. Expression of its ligand, TNF-like cytokine 1A (TL1A), on mouse tumor cells has been shown to promote tumor regression. This study aimed to devel
Externí odkaz:
https://doaj.org/article/242097bbe4bd4a5fbe2ac2f165b5bac3
Autor:
Juan Liu, Fengfeng Mao, Jianhe Chen, Shuaiyao Lu, Yonghe Qi, Yinyan Sun, Linqiang Fang, Man Lung Yeung, Chunmei Liu, Guimei Yu, Guangyu Li, Ximing Liu, Yuansheng Yao, Panpan Huang, Dongxia Hao, Zibing Liu, Yu Ding, Haimo Liu, Fang Yang, Pan Chen, Rigai Sa, Yao Sheng, Xinxin Tian, Ran Peng, Xue Li, Junmian Luo, Yurui Cheng, Yule Zheng, Yongqing Lin, Rui Song, Ronghua Jin, Baoying Huang, Hyeryun Choe, Michael Farzan, Kwok-Yung Yuen, Wenjie Tan, Xiaozhong Peng, Jianhua Sui, Wenhui Li
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Many of the currently available COVID-19 vaccines and therapeutics are not effective against newly emerged SARS-CoV-2 variants. Here, we developed the metallo-enzyme domain of angiotensin converting enzyme 2 (ACE2)—the cellular receptor of
Externí odkaz:
https://doaj.org/article/8b118b6b063b457f8f4c4940e76438c7
Autor:
Yulu Li, Juan Liu, Wei Chen, Wei Wang, Fang Yang, Ximing Liu, Yao Sheng, Kaixin Du, Miaomiao He, Xueyuan Lyu, Huiyu Li, Linlin Zhao, Zhizhong Wei, Fengchao Wang, Sanduo Zheng, Jianhua Sui
Publikováno v:
Journal of Hematology & Oncology, Vol 16, Iss 1, Pp 1-21 (2023)
Abstract Background The antiphagocytic molecule CD47 is overexpressed in a wide variety of cancer cells, and antibodies targeting CD47 for cancer therapies are currently under intensive investigation. However, owing to the ubiquitous expression of CD
Externí odkaz:
https://doaj.org/article/45ba5542937440ee88d454d7a569d7e1
Autor:
Ximing Liu, Xinxin Tian, Xinyan Hao, Huixiang Zhang, Kailun Wang, Zhizhong Wei, Xin Wei, Yulu Li, Jianhua Sui
Publikováno v:
Molecular Therapy: Oncolytics, Vol 27, Iss , Pp 256-269 (2022)
The clinical use of anti-EGFR antibody-based cancer therapy has been limited by antibody-EGFR binding in normal tissues, so developing pH-dependent anti-EGFR antibodies that selectively bind with EGFR in tumors—by taking advantage of the acidity of
Externí odkaz:
https://doaj.org/article/00f74d401b4742418651e982216ef3a3
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Nbr1 recognizes cargos in selective autophagy. Here, authors show filamentous yeast Nbr1 binds Ams1 via an FW domain, and the cryo-EM structure reveals that Nbr1 recognizes the N-terminal di-glycine and tetrameric assembly of Ams1.
Externí odkaz:
https://doaj.org/article/d93bf904f03c4b91982388b429217392
Autor:
Li Zhong, Dan Liao, Jingjing Li, Wenqiang Liu, Jingxuan Wang, Cuiling Zeng, Xin Wang, Zhiliang Cao, Ruhua Zhang, Miao Li, Kuntai Jiang, Yi-Xin Zeng, Jianhua Sui, Tiebang Kang
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 6, Iss 1, Pp 1-16 (2021)
Abstract It remains unknown for decades how some of the therapeutic fusion proteins positive in a small percentage of cancer cells account for patient outcome. Here, we report that osteosarcoma Rab22a-NeoF1 fusion protein, together with its binding p
Externí odkaz:
https://doaj.org/article/aa7c7241ec6445e399e13a980ba1f3f5
Autor:
Fengfeng Mao, Meng-Xuan Wang, Xinfeng Hou, Zhongmin Zhou, Yan-Yan Yan, Ling-Juan Fang, Zexi Tan, Wei-Yuan Fang, Teng Liu, Wenhui He, Cong Li, Xin-Bao Xie, Shi-Qi Lu, Jianhua Sui, Fengchao Wang, Jun Han, Jian-She Wang, Wenhui Li
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 3, Pp 831-839 (2021)
Externí odkaz:
https://doaj.org/article/72e1b885f4274c9791fc295b9e5aac83
Autor:
Dingbin Tang, Hanqing Zhao, Yumeng Wu, Bo Peng, Zhenchao Gao, Yinyan Sun, Jinzhi Duan, Yonghe Qi, Yunfei Li, Zhongmin Zhou, Guilan Guo, Yu Zhang, Cheng Li, Jianhua Sui, Wenhui Li
Publikováno v:
Cell Reports, Vol 35, Iss 13, Pp 109288- (2021)
Summary: The hepatitis B virus (HBV) infects 257 million people worldwide. HBV infection requires establishment and persistence of covalently closed circular (ccc) DNA, a viral episome, in nucleus. Here, we study cccDNA spatial localization in the 3D
Externí odkaz:
https://doaj.org/article/f10902dffb3d412496b93589006a0e64
Autor:
Ying Yan, Lena Allweiss, Danli Yang, Jingting Kang, Jianwen Wang, Xiangjun Qian, Ting Zhang, Hui Liu, Lu Wang, Shuhong Liu, Jianhua Sui, Xiangmei Chen, Maura Dandri, Jingmin Zhao, Fengmin Lu
Publikováno v:
Emerging Microbes and Infections, Vol 8, Iss 1, Pp 879-894 (2019)
ABSTRACTHepatocyte proliferation could result in the loss of covalently closed circular DNA (cccDNA) and the emergence of cccDNA-cleared nascent hepatocytes, which appear refractory to hepatitis B virus (HBV) reinfection with unknown mechanism(s). So
Externí odkaz:
https://doaj.org/article/8ecaf7f5b5af477780b48d34e54969f1
Autor:
Yuval Avnir, Kristina L. Prachanronarong, Zhen Zhang, Shurong Hou, Eric C. Peterson, Jianhua Sui, Hatem Zayed, Vinodh B. Kurella, Andrew T. McGuire, Leonidas Stamatatos, Brendan J. Hilbert, Markus-Frederik Bohn, Timothy F. Kowalik, Jeffrey D. Jensen, Robert W. Finberg, Jennifer P. Wang, Margaret Goodall, Roy Jefferis, Quan Zhu, Nese Kurt Yilmaz, Celia A. Schiffer, Wayne A. Marasco
Publikováno v:
Cell Reports, Vol 21, Iss 11, Pp 3243-3255 (2017)
The heavy chain IGHV1-69 germline gene exhibits a high level of polymorphism and shows biased use in protective antibody (Ab) responses to infections and vaccines. It is also highly expressed in several B cell malignancies and autoimmune diseases. G6
Externí odkaz:
https://doaj.org/article/2bbb54bf6c2c4cf88bc9275ff9a8c706