Zobrazeno 1 - 10
of 374
pro vyhledávání: '"Jianhua Mao"'
Autor:
Guozhen Wang, Mengqiu Liao, Danny Junyi Tan, Xiangjun Chen, Ran Chao, Yifan Zhu, Pan Li, Yuelin Guan, Jianhua Mao, Lidan Hu
Publikováno v:
Kidney Diseases, Pp 1-26 (2024)
Background: Inherited kidney diseases (IKD) in children present unique diagnostic and therapeutic challenges. IKD stand as a formidable challenge on patient quality of life, morbidity, mortality, and cost to the healthcare system. With over 150 genet
Externí odkaz:
https://doaj.org/article/a5a19c681ed04134877615d7ed15f607
Publikováno v:
Kidney Diseases, Pp 1-14 (2024)
Background: Nephrotic syndrome is a special type of chronic kidney disease, the specific pathogenesis of which remains unclear. An increasing number of studies have suggested that B cells play an important role in the pathogenesis of nephrotic syndro
Externí odkaz:
https://doaj.org/article/2c07cede0846436f97cb6bd95e73636f
Publikováno v:
BMC Neurology, Vol 24, Iss 1, Pp 1-9 (2024)
Abstract Background Calcification is common in advanced atheromatous plaque, but its clinical significance remains unclear. This study aimed to assess the prevalence of plaque calcification in the moderate-to-severe internal carotid artery stenosis a
Externí odkaz:
https://doaj.org/article/ac95aed256a7442a81630aa559716fae
Autor:
Lu Li, Fei Liu, Chunyue Feng, Zhenjie Chen, Nan Zhang, Jianhua Mao, Xiangxiang Pan, Peifang Wei
Publikováno v:
Chinese Medical Journal, Vol 137, Iss 9, Pp 1044-1053 (2024)
Abstract. Over the past decade, mitochondrial dysfunction has been investigated as a key contributor to acute and chronic kidney disease. However, the precise molecular mechanisms linking mitochondrial damage to kidney disease remain elusive. The rec
Externí odkaz:
https://doaj.org/article/00e930eb9c704abc8c94142ca18a0e56
Autor:
Yanyan Jin, Xue He, Weiqiang Lin, Zhaoyang Peng, Wei Li, Weiqing Xiang, Zhihui Chen, Haidong Fu, Jianhua Mao
Publikováno v:
Biomolecules & Biomedicine (2024)
This study aimed to discover novel serum biomarkers for IgA vasculitis with nephritis (IgAVN). The serum of IgA vasculitis (IgAV) patients without nephritis and IgAVN patients not treated with glucocorticoids was analyzed for 440 proteins using a nov
Externí odkaz:
https://doaj.org/article/6abfb12fe4a143dea8b323bb3e05abf9
Publikováno v:
Renal Failure, Vol 46, Iss 2 (2024)
The transient receptor potential canonical 6 (TRPC6) channel, a nonselective cation channel that allows the passage of Ca2+, plays an important role in renal diseases. TRPC6 is activated by Ca2+ influx, oxidative stress, and mechanical stress. Studie
Externí odkaz:
https://doaj.org/article/c7b16616dfcf4d9baa62ff649b3be993
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-15 (2023)
Abstract Background This study aimed to identify an orcl1 mutation in a patient with Dent-2 Disease and investigate the underlying mechanisms. Methods The ocrl1 mutation was identified through exome sequencing. Knockdown of orcl1 and overexpression o
Externí odkaz:
https://doaj.org/article/b3ebfeba2cf54cb4855e3b2512691340
Autor:
Li Lin, Yuhong Ye, Haidong Fu, Weizhong Gu, Manli Zhao, Jingmiao Sun, Zhongkai Cao, Guoping Huang, Yi Xie, Fei Liu, Lu Li, Qiuyu Li, Jianhua Mao, Lidan Hu
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-15 (2023)
Abstract Background Steroid-resistant nephrotic syndrome (SRNS) is characterized by unrelieved proteinuria after an initial 4–8 weeks of glucocorticoid therapy. Genes in podocytes play an important role in causing SRNS. Objective This study aimed t
Externí odkaz:
https://doaj.org/article/084c9fdc16784bd9997de7973a0d265a
Publikováno v:
Kidney Diseases, Pp 1-7 (2023)
Background: Hypoxia-inducible factor-prolyl hydroxylase inhibitors (HIF-PHIs) are novel oral agents used for renal anemia treatment. Roxadustat, a first-in-class HIF-PHI used for treating anemia in chronic kidney disease patients, has been approved i
Externí odkaz:
https://doaj.org/article/cf91b362d4014d2a9a1f2c0f0d1fb29e
Autor:
Qing Ye, Hanyan Meng, Fang Ye, Haidong Fu, Jingjing Wang, Fei Liu, Huijun Shen, Yu Bao, Chunyue Feng, Xiaojing Zhang, Guoping Huang, Yi Xie, Xiujuan Zhu, Manli Zhao, Guoji Guo, Jianhua Mao
Publikováno v:
Clinical and Translational Medicine, Vol 14, Iss 4, Pp n/a-n/a (2024)
Externí odkaz:
https://doaj.org/article/91e9a061792540e3b290b184af2bec84