Zobrazeno 1 - 10
of 221
pro vyhledávání: '"Jianhua CHANG"'
Autor:
Qiao Li, Ying Cheng, Zhongsheng Tong, Yunjiang Liu, Xian Wang, Min Yan, Jianhua Chang, Shusen Wang, Caiwen Du, Liang Li, Chunjiao Wu, Mingxia Wang, Zhuo Wang, Zhuli Wu, Xingli Wang, Yongli Jin, Lei Diao, Yi Sun, Yongjiao Zhang, Ai-Min Hui, Binghe Xu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-10 (2024)
Abstract Currently approved HER2-targeting antibody-drug conjugates (ADCs) for HER2-positive breast cancer (BC) are associated with safety concerns. In this multicenter, single-arm, dose-escalation (phase 1a) and dose-expansion (phase 1b) phase 1 tri
Externí odkaz:
https://doaj.org/article/a970daa7143b4f0c9d62cb86b63129d8
Autor:
Caicun Zhou, MD, PhD, You Lu, MD, Sang-We Kim, MD, PhD, Thanyanan Reungwetwattana, MD, Jianying Zhou, MD, Yiping Zhang, MD, Jianxing He, MD, PhD, Jin-Ji Yang, MD, Ying Cheng, MD, Se-Hoon Lee, MD, PhD, Jianhua Chang, MD, Jian Fang, MD, Zhe Liu, PhD, Lilian Bu, MSc, Li Qian, MD, Tingting Xu, MD, Venice Archer, MB ChB, MSc, Magalie Hilton, MSc, Mingzhu Zhou, MSc, Li Zhang, MD
Publikováno v:
JTO Clinical and Research Reports, Vol 5, Iss 9, Pp 100700- (2024)
Introduction: Previous results from the phase 3 ALESIA study (NCT02838420) revealed that alectinib (a central nervous system [CNS]-active, ALK inhibitor) had clinical benefits in treatment-naïve Asian patients with advanced ALK-positive NSCLC, consi
Externí odkaz:
https://doaj.org/article/0adb5b401a534eba8c323105cdaa5a38
Autor:
Yuanyuan Li, Jiaxin Xie, Yu Sun, He Zhang, Chuansheng Xia, Min Wang, Tianjie Wang, Jianhua Chang, Qiannan Cui
Publikováno v:
AIP Advances, Vol 14, Iss 6, Pp 065326-065326-7 (2024)
Nanometer scale light penetration depths of halide perovskite (HP) set an intrinsic limit on the performance improvement of optoelectronic devices. Here, we show that two-photon excitation can overcome this limit by markedly increasing the light pene
Externí odkaz:
https://doaj.org/article/6e12ba49028b41da86893112010d0736
Autor:
Ru Xu, Peng Chen, Xiancheng Liu, Jianguo Zhao, Tinggang Zhu, Dunjun Chen, Zili Xie, Jiandong Ye, Xiangqian Xiu, Fayu Wan, Jianhua Chang, Rong Zhang, Youdou Zheng
Publikováno v:
Chip, Vol 3, Iss 1, Pp 100079- (2024)
GaN power electronic devices, such as the lateral AlGaN/GaN Schottky barrier diode (SBD), have received significant attention in recent years. Many studies have focused on optimizing the breakdown voltage (BV) of the device, with a particular emphasi
Externí odkaz:
https://doaj.org/article/184b0a5faca8417593d4349b32f97d1e
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-14 (2023)
Abstract Objectives ICIs have become the standard treatment for advanced NSCLC patients. Currently, PD-L1 is the most widely useful biomarker to predict ICI efficacy, but the sensitivity and specificity are limited. Therefore, the useful predictive b
Externí odkaz:
https://doaj.org/article/fb1fc77272b747c08ff77c0017a9b19b
Autor:
Bowen Xu, Wei Zhao, Jianhua Chang, Jinghua Yin, Nan Wang, Zhaoru Dong, Xuting Zhi, Tao Li, Zhiqiang Chen
Publikováno v:
World Journal of Surgical Oncology, Vol 21, Iss 1, Pp 1-11 (2023)
Abstract Background Peri-hilar cholangiocarcinoma (pCCA) is a unique entity, and radical surgery provides the only chance for cure and long-term survival. But it is still under debate which surgical strategy (i.e., left-sided hepatectomy, LH or right
Externí odkaz:
https://doaj.org/article/3d78a84ca6f04fc8aff6d62fa0935da0
Autor:
Fengying Wu, Tao Jiang, Gongyan Chen, Yunchao Huang, Jianying Zhou, Lizhu Lin, Jifeng Feng, Zhehai Wang, Yongqian Shu, Jianhua Shi, Yi Hu, Qiming Wang, Ying Cheng, Jianhua Chen, Xiaoyan Lin, Yongsheng Wang, Jianan Huang, Jiuwei Cui, Lejie Cao, Yunpeng Liu, Yiping Zhang, Yueyin Pan, Jun Zhao, LiPing Wang, Jianhua Chang, Qun Chen, Xiubao Ren, Wei Zhang, Yun Fan, Zhiyong He, Jian Fang, Kangsheng Gu, Xiaorong Dong, Tao Zhang, Wei Shi, Jianjun Zou, Xuejuan Bai, Shengxiang Ren, Caicun Zhou, the CameL Study Group
Publikováno v:
Cancer Communications, Vol 42, Iss 12, Pp 1331-1346 (2022)
Abstract Background Although programmed cell death 1 (PD‐1) blockade plus chemotherapy can significantly prolong the progression‐free survival (PFS) and overall survival (OS) in first‐line settings in patients with driver‐negative advanced no
Externí odkaz:
https://doaj.org/article/29c625b2073e4405bfa35cd6c6aed633
Publikováno v:
IEEE Photonics Journal, Vol 14, Iss 4, Pp 1-6 (2022)
In this paper, we propose a novel ultrafast laser with nanostructure CH3NH3PbI3 nanorods, yielding a higher modulation depth and lower optical loss. Our experiment is performed through nanopatterned CH3NH3PbI3 rods and an all-solid-state passive mode
Externí odkaz:
https://doaj.org/article/4183d570a4f142d3996a92c1b8146c93
Autor:
Shun Lu, Ying Cheng, Jianying Zhou, Mengzhao Wang, Jun Zhao, Baocheng Wang, Gongyan Chen, Jifeng Feng, Zhiyong Ma, Lin Wu, Changli Wang, Kewei Ma, Shucai Zhang, Jun Liang, Yong Song, Jie Wang, Yi-Long Wu, Ang Li, Yizhi Huang, Jianhua Chang
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 14 (2022)
Background: Nivolumab has been approved in China as second-line treatment for advanced non-small-cell lung cancer (NSCLC) via weight-based infusion, based on the CheckMate 078 study. We investigated the safety and efficacy of 240 mg flat-dose nivolum
Externí odkaz:
https://doaj.org/article/0573323047e24e7f8830338141bd5c24
Publikováno v:
Crystals, Vol 13, Iss 7, p 1145 (2023)
Nonpolar (112¯0) a-plane GaN films were grown on semipolar (11¯02) r-plane sapphire substrates using various buffer layers within a low-pressure metal organic chemical vapor deposition system. The structural properties of nonpolar a-plane GaN films
Externí odkaz:
https://doaj.org/article/0dbd068a22524492898cbf45461b76c6