Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Jianheng Ye"'
Autor:
Ren Liu, Zhihao Zou, Lingwu Chen, Yuanfa Feng, Jianheng Ye, Yulin Deng, Xuejin Zhu, Yixun Zhang, Jundong Lin, Shanghua Cai, Zhenfeng Tang, Yingke Liang, Jianming Lu, Yangjia Zhuo, Zhaodong Han, Xiaohui Ling, Yuxiang Liang, Zongren Wang, Weide Zhong
Publikováno v:
Cell Death and Disease, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Renal cell carcinoma (RCC) is one of the three major malignant tumors of the urinary system and originates from proximal tubular epithelial cells. Clear cell renal cell carcinoma (ccRCC) accounts for approximately 80% of RCC cases and is rec
Externí odkaz:
https://doaj.org/article/6891daa6392c4c2e9cf958ebc5a5ad49
Autor:
Jianheng Ye, Shanghua Cai, Yuanfa Feng, Jinchuang Li, Zhiduan Cai, Yulin Deng, Ren Liu, Xuejin Zhu, Jianming Lu, Yangjia Zhuo, Yingke Liang, Jianjiang Xie, Yanqiong Zhang, Huichan He, Zhaodong Han, Zhenyu Jia, Weide Zhong
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-15 (2023)
Abstract The therapeutic efficacy of metformin in prostate cancer (PCa) appears uncertain based on various clinical trials. Metformin treatment failure may be attributed to the high frequency of transcriptional dysregulation, which leads to drug resi
Externí odkaz:
https://doaj.org/article/2376bd6bb3a54b9a98270b5490f976eb
Autor:
Hongxiang Liu, Yong Luo, Shankun Zhao, Jing Tan, Minjian Chen, Xihai Liu, Jianheng Ye, Shanghua Cai, Yulin Deng, Jinchuang Li, Huichan He, Xin Zhang, Weide Zhong
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BackgroundClear cell renal cell carcinoma (ccRCC) is a malignant disease containing tumor-infiltrating lymphocytes. Reactive oxygen species (ROS) are present in the tumor microenvironment and are strongly associated with cancer development. Neverthel
Externí odkaz:
https://doaj.org/article/f45e4641bc9146c2a6ca7a4ee9a0077b
Autor:
Yuanfa Feng, Yulin Deng, Zhenfeng Tang, Shanghua Cai, Jinchuang Li, Ren Liu, Jiaming Wan, Huichan He, Guohua Zeng, Jianheng Ye, Zhaodong Han, Weide Zhong
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
BackgroundEnzalutamide, as a second-generation endocrine therapy drug for prostate cancer (PCa), is prominent representative among the synthetic androgen receptor antagonists. Currently, there is lack of enzalutamide-induced signature (ENZ-sig) for p
Externí odkaz:
https://doaj.org/article/91c2612ac6424a91be51dcd91b1e24bf
Autor:
Yulin Deng, Kai Guo, Zhenfeng Tang, Yuanfa Feng, Shanghua Cai, Jianheng Ye, Yuanxue Xi, Jinchuang Li, Ren Liu, Chao Cai, Zeheng Tan, Yixun Zhang, Zhaodong Han, Guohua Zeng, Weide Zhong
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Clear cell renal cell carcinoma (ccRCC) is a common aggressive malignant tumor of the urinary system. Given the heterogeneity of the tumor microenvironment, immunotherapy may not fully exert its role in the treatment of advanced patients. Long noncod
Externí odkaz:
https://doaj.org/article/110fbdf2ed484288a94b3a096f68fb82
Autor:
Ren Liu, Yuanfa Feng, Yulin Deng, Zhihao Zou, Jianheng Ye, Zhiduan Cai, Xuejin Zhu, Yingke Liang, Jianming Lu, Hui Zhang, Yong Luo, Zhaodong Han, Yangjia Zhuo, Qingling Xie, Chi Tin Hon, Yuxiang Liang, Chin-Lee Wu, Weide Zhong
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-17 (2021)
Abstract Background Hypoxia signaling, especially the hypoxia inducible factor (HIF) pathway, is a major player in clear cell renal cell carcinoma (ccRCC), which is characterized by disorders in lipid and glycogen metabolism. However, the interaction
Externí odkaz:
https://doaj.org/article/8940ef0e98b142c895dc0934bb538769
Autor:
Zhaodong Han, Rujun Mo, Shanghua Cai, Yuanfa Feng, Zhenfeng Tang, Jianheng Ye, Ren Liu, Zhiduan Cai, Xuejin Zhu, Yulin Deng, Zhihao Zou, Yongding Wu, Zhouda Cai, Yuxiang Liang, Weide Zhong
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Given the tumor heterogeneity, most of the current prognostic indicators cannot accurately evaluate the prognosis of patients with prostate cancer, and thus, the best opportunity to intervene in the progression of this disease is missed. E2F transcri
Externí odkaz:
https://doaj.org/article/783be7f672624342bf987c71174c8ac1
Autor:
Rui Zhou, Yuanfa Feng, Jianheng Ye, Zhaodong Han, Yuxiang Liang, Qingbiao Chen, Xiaoming Xu, Yuhan Huang, Zhenyu Jia, Weide Zhong
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Tumor-adjacent normal (TAN) tissues, which constitute tumor microenvironment and are different from healthy tissues, provide critical information at molecular levels that can be used to differentiate aggressive tumors from indolent tumors. In this st
Externí odkaz:
https://doaj.org/article/640e301d5ee6464481cbc82292974042
Autor:
Xuejin Zhu, Yangjia Zhuo, Shulin Wu, Yanfei Chen, Jianheng Ye, Yulin Deng, Yuanfa Feng, Ren Liu, Shanghua Cai, Zhihao Zou, Bin Wang, Chin-Lee Wu, Guohua Zeng, Weide Zhong
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Externí odkaz:
https://doaj.org/article/6168d38d1abf40e3b94b5e45bebda40e
Autor:
Xuejin Zhu, Yangjia Zhuo, Shulin Wu, Yanfei Chen, Jianheng Ye, Yulin Deng, Yuanfa Feng, Ren Liu, Shanghua Cai, Zhihao Zou, Bin Wang, Chin-Lee Wu, Guohua Zeng, Weide Zhong
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Transcription factor EB (TFEB), a member of the MiT family, is dysregulated in different cancers and exerts specific biological functions within the tumor microenvironment. Downregulation of TFEB induces macrophage polarization in the TME and promote
Externí odkaz:
https://doaj.org/article/2a32b904db694b6f9534f87731b4a09e