Zobrazeno 1 - 10
of 149
pro vyhledávání: '"Jianhai Du"'
Autor:
San Joon Lee, Douglas Emery, Eric Vukmanic, Yekai Wang, Xiaoqin Lu, Wei Wang, Enzo Fortuny, Robert James, Henry J. Kaplan, Yongqing Liu, Jianhai Du, Douglas C. Dean
Publikováno v:
Cell Reports, Vol 42, Iss 9, Pp 113054- (2023)
Summary: Most mutations in retinitis pigmentosa (RP) arise in rod photoreceptors, but cone photoreceptors, responsible for high-resolution daylight and color vision, are subsequently affected, causing the most debilitating features of the disease. We
Externí odkaz:
https://doaj.org/article/c20af539eead47ddb69cee12d9909f6d
Autor:
Yingying Chen, Ting Zhang, Shaoxue Zeng, Rong Xu, Kaiyu Jin, Nathan J. Coorey, Yekai Wang, Ke Wang, So-Ra Lee, Michelle Yam, Meidong Zhu, Andrew Chang, Xiaohui Fan, Meixia Zhang, Jianhai Du, Mark C. Gillies, Ling Zhu
Publikováno v:
Redox Biology, Vol 54, Iss , Pp 102379- (2022)
The Pentose Phosphate Pathway (PPP), a metabolic offshoot of the glycolytic pathway, provides protective metabolites and molecules essential for cell redox balance and survival. Transketolase (TKT) is the critical enzyme that controls the extent of
Externí odkaz:
https://doaj.org/article/0ce3a94aebc246339b810da98df48f47
Autor:
Jun Yang, Jianhai Du
Publikováno v:
Frontiers in Energy Research, Vol 10 (2022)
To reduce the operating cost and enhance the energy utilization efficiency of the integrated energy system (IES), an economic dispatch algorithm is proposed based on finite-time double-consensus. First, an economic dispatch model of IES under two mod
Externí odkaz:
https://doaj.org/article/5bf8385b528a417fa841bd078ba4dacb
Autor:
David Sokolov, Emily R Sechrest, Yekai Wang, Connor Nevin, Jianhai Du, Saravanan Kolandaivelu
Publikováno v:
eLife, Vol 10 (2021)
Despite mounting evidence that the mammalian retina is exceptionally reliant on proper NAD+ homeostasis for health and function, the specific roles of subcellular NAD+ pools in retinal development, maintenance, and disease remain obscure. Here, we sh
Externí odkaz:
https://doaj.org/article/a7fa7f4bb4f44504ae3e7542438b2627
Publikováno v:
Bio-Protocol, Vol 11, Iss 4 (2021)
Nitrogen-containing metabolites including ammonia, amino acids, and nucleotides, are essential for cell metabolism, growth, and neural transmission. Nitrogen metabolism is tightly coordinated with carbon metabolism in the breakdown and biosynthesis o
Externí odkaz:
https://doaj.org/article/7a9482b369ff49f19d8c95fd1b0af9c3
Autor:
Bo Li, Ting Zhang, Wei Liu, Yekai Wang, Rong Xu, Shaoxue Zeng, Rui Zhang, Siyan Zhu, Mark C. Gillies, Ling Zhu, Jianhai Du
Publikováno v:
iScience, Vol 23, Iss 11, Pp 101672- (2020)
Summary: Photoreceptors, especially cones, which are enriched in the human macula, have high energy demands, making them vulnerable to metabolic stress. Metabolic dysfunction of photoreceptors and their supporting retinal pigment epithelium (RPE) is
Externí odkaz:
https://doaj.org/article/354036a6aa874d01b92f8a62b43159a3
Publikováno v:
Tehnički Vjesnik, Vol 25, Iss 3, Pp 820-830 (2018)
A Safety-Critical System (SCS), such as a spacecraft, is usually a complex system. It produces a large amount of test data during a comprehensive testing process. The large amount of data is often managed by a comprehensive test data query system. Th
Externí odkaz:
https://doaj.org/article/231da65789494964b68e1215da89d7e4
Autor:
Wei Wang, Ashwini Kini, Yekai Wang, Tingting Liu, Yao Chen, Eric Vukmanic, Douglas Emery, Yongqing Liu, Xiaoqin Lu, Lei Jin, San Joon Lee, Patrick Scott, Xiao Liu, Kevin Dean, Qingxian Lu, Enzo Fortuny, Robert James, Henry J. Kaplan, Jianhai Du, Douglas C. Dean
Publikováno v:
Cell Reports, Vol 28, Iss 5, Pp 1323-1334.e4 (2019)
Summary: Retinitis pigmentosa (RP) initiates with diminished rod photoreceptor function, causing peripheral and night-time vision loss. However, subsequent loss of cone function and high-resolution daylight and color vision is most debilitating. Visu
Externí odkaz:
https://doaj.org/article/be5ef88a3258497aa42181b88cc792bc
Autor:
Ting Zhang, Ling Zhu, Michele C Madigan, Wei Liu, Weiyong Shen, Svetlana Cherepanoff, Fanfan Zhou, Shaoxue Zeng, Jianhai Du, Mark C Gillies
Publikováno v:
eLife, Vol 8 (2019)
The human macula is more susceptible than the peripheral retina to developing blinding conditions such as age-related macular degeneration, diabetic retinopathy. A key difference between them may be the nature of their Müller cells. We found primary
Externí odkaz:
https://doaj.org/article/2448b4f984bc421eb82e42f57438ca08
Autor:
Mark A Kanow, Michelle M Giarmarco, Connor SR Jankowski, Kristine Tsantilas, Abbi L Engel, Jianhai Du, Jonathan D Linton, Christopher C Farnsworth, Stephanie R Sloat, Austin Rountree, Ian R Sweet, Ken J Lindsay, Edward D Parker, Susan E Brockerhoff, Martin Sadilek, Jennifer R Chao, James B Hurley
Publikováno v:
eLife, Vol 6 (2017)
Here we report multiple lines of evidence for a comprehensive model of energy metabolism in the vertebrate eye. Metabolic flux, locations of key enzymes, and our finding that glucose enters mouse and zebrafish retinas mostly through photoreceptors su
Externí odkaz:
https://doaj.org/article/aff27e94dd9b414d9153404c6b6c9551