Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Jiangzhong Yao"'
Autor:
Chunquan Sheng, Shengzheng Wang, Yang Liu, Guoqiang Dong, Wannian Zhang, Yunyang Wei, Yuelin Wu, Zhenyuan Miao, Xiao Min, Shiping Zhu, Shanchao Wu, Jin Li, Chunlin Zhuang, Jiangzhong Yao, Huojun Zhang, Zhiliang Yu
Publikováno v:
European Journal of Medicinal Chemistry. 82:545-551
In an effort to expand the structure-activity relationship of the natural anticancer compound piperlongumine, we have prepared sixteen novel piperlongumine derivatives with halogen or morpholine substituents at C2 and alkyl substituents at C7. Most o
Autor:
Guoqiang Dong, Lei Zhou, Xiaoying Che, Jing Zhang, Wenfeng Liu, Wei Guo, Pengfei Cheng, Hao Feng, Juan Wang, Zhenyuan Miao, Chunquan Sheng, Wenya Wang, Chuan Luo, Jiangzhong Yao, Wannian Zhang, Yulan Xu, Liang You, Lin-Jian Zhu
Publikováno v:
Bioorganicmedicinal chemistry. 18(9)
Homocamptothecins (hCPTs) represents a new promising class of topoisomerase I inhibitors with enhanced stability and superior antitumor activity. Some phosphodiesters and phosphotriesters homocamptothecin derivatives were designed and synthesized bas