Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Jiangyu Yan"'
Publikováno v:
Cell Division, Vol 19, Iss 1, Pp 1-12 (2024)
Abstract Background Nasopharyngeal carcinoma (NPC) is a malignant tumor with poor survival rate. G2 and S phase-expressed‐1 (GTSE1) takes part in the progression of diverse tumors as an oncogene, but its role and potential mechanism in NPC remain u
Externí odkaz:
https://doaj.org/article/62019b6e55194ed2ba705c68b6effe8e
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundIt has been previously demonstrated that intestinal barrier damage is one of the underlying mechanisms leading to frailty in non-HIV-infected aging populations. However, there is a paucity of direct evidence which demonstrates the associati
Externí odkaz:
https://doaj.org/article/381d5268a10c4660bda5e4cd2c319550
Publikováno v:
Heliyon, Vol 10, Iss 11, Pp e31789- (2024)
Perforation of the tympanic membrane (TM) is a common condition that often requires a scaffold as a support for surgery. However, because of the external environment of the auditory canal, the scaffold could become bacterially infected and prevent th
Externí odkaz:
https://doaj.org/article/c3b6924328b5468a86d295c2b31e7d0b
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 29, Iss 7, p 240 (2024)
Background: Uncontrolled cellular proliferation may result in the progression of diseases such as cancer that promote organism death. Programmed cell death (PCD) is an important mechanism that ensures the quality and quantity of cells, which could be
Externí odkaz:
https://doaj.org/article/9213895f02244397a2e8483ccedd5257
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-7 (2022)
Abstract Age-related hearing loss (ARHL) represents the frequently occurring disability that affects the elderly worldwide. The recent evidence has calculated ARHL to be most potential risk factor to predict dementia. β-amyloid plaques and tau accum
Externí odkaz:
https://doaj.org/article/2008fa693b644170b4025fcd7f20a94a
Autor:
Jing Ouyang, Jiangyu Yan, Xin Zhou, Stéphane Isnard, Vijay Harypursat, Hongjuan Cui, Jean-Pierre Routy, Yaokai Chen
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
The intestinal barrier has the daunting task of allowing nutrient absorption while limiting the entry of microbial products into the systemic circulation. HIV infection disrupts the intestinal barrier and increases intestinal permeability, leading to
Externí odkaz:
https://doaj.org/article/8676dfdac6154b069462e8685a715544
Autor:
Jing Ouyang, Jiangyu Yan, Xin Zhou, Stéphane Isnard, Shengquan Tang, Cecilia T. Costiniuk, Yaling Chen, Jean-Pierre Routy, Yaokai Chen
Publikováno v:
Journal of Fungi, Vol 9, Iss 10, p 963 (2023)
People living with HIV (PLWH) display altered gut epithelium that allows for the translocation of microbial products, contributing to systemic immune activation. Although there are numerous studies which examine the gut bacterial microbiome in PLWH,
Externí odkaz:
https://doaj.org/article/c10235b947aa4e30833f22ae1e439f4e
Autor:
Yaling Chen, Jing Ouyang, Stéphane Isnard, Cecilia T. Costiniuk, Jiangyu Yan, Xin Zhou, Jean-Pierre Routy, Yaokai Chen, Wei Zhao
Publikováno v:
Infectious Diseases & Immunity, Vol 2, Iss 2, Pp 122-124 (2022)
Abstract. Increased microbial translocation and chronic immune activation are two critical problems for people living with HIV (PLWH) in the antiretroviral therapy (ART) era. Compared with numerous studies on bacterial microbiomic communities, there
Externí odkaz:
https://doaj.org/article/9591e423aebb46ef946dc1ee838063b2
Autor:
Jiangyu Yan, Jing Ouyang, Stéphane Isnard, Xin Zhou, Vijay Harypursat, Jean-Pierre Routy, Yaokai Chen
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The intestinal microbiome is an essential so-called human “organ”, vital for the induction of innate immunity, for metabolizing nutrients, and for maintenance of the structural integrity of the intestinal barrier. HIV infection adversely influenc
Externí odkaz:
https://doaj.org/article/670b0c42850e49c8abf720353149421c
Autor:
Qi Pan, Shushan Lin, Yu Li, Liang Liu, Xiaoping Li, Xianglei Gao, Jiangyu Yan, Baohua Gu, Xiaofeng Chen, Wenjia Li, Xinfa Tang, Chao Chen, Lixin Guo
Publikováno v:
EBioMedicine, Vol 63, Iss , Pp 103202- (2021)
Background: Fibroblast growth factor 21 (FGF21) has become a promising therapeutic target for metabolic diseases such as type 2 diabetes (T2D), obesity and non-alcoholic steatohepatitis. However, the clinical application of natural FGF21 molecule is
Externí odkaz:
https://doaj.org/article/7e596c8625a2436db136e1239e8fa2dd