Zobrazeno 1 - 10
of 198
pro vyhledávání: '"Jianguo G Gu"'
Publikováno v:
Molecular Brain, Vol 16, Iss 1, Pp 1-15 (2023)
Abstract Nav1.8-positive afferent fibers are mostly nociceptors playing a role in mediating thermal and mechanical pain, but mechanoreceptors within these afferents have not been fully investigated. In this study, we generated mice expressing channel
Externí odkaz:
https://doaj.org/article/5d5b7e90d12849fd83bb2465f4d40c49
Publikováno v:
Molecular Brain, Vol 15, Iss 1, Pp 1-14 (2022)
Abstract Previous immunohistochemical studies have shown the expression of KCNQ2 channels at nodes of Ranvier (NRs) of myelinated nerves. However, functions of these channels at NRs remain elusive. In the present study, we addressed this issue by dir
Externí odkaz:
https://doaj.org/article/6dd6783936a341dca824476028716265
Autor:
Timothy J. Ness, Cary DeWitte, Jennifer J. DeBerry, Morgan P. Hart, Buffie Clodfelder-Miller, Jianguo G. Gu, Jennifer Ling, Alan Randich
Publikováno v:
Frontiers in Pain Research, Vol 2 (2021)
This report describes methodological and exploratory investigations of the zymosan-induced neonatal bladder inflammation (NBI) model of interstitial cystitis/bladder pain syndrome (IC/BPS) in female rats. These results validate and extend the current
Externí odkaz:
https://doaj.org/article/4a316e54200f40fc9879f19edc02f464
Publikováno v:
Molecular Brain, Vol 12, Iss 1, Pp 1-4 (2019)
Abstract Merkel discs, located in skin touch domes and whisker hair follicles, are tactile end organs essential for environmental exploration, social interaction, and tactile discrimination. Recent studies from our group and two others have shown tha
Externí odkaz:
https://doaj.org/article/80ede470814e431d9a05a50fc739fadb
Publikováno v:
STAR Protocols, Vol 2, Iss 1, Pp 100266- (2021)
Summary: The patch-clamp recording technique is indispensable for studying ion channel functions of cells but is challenging to apply to the node of Ranvier, a key site where action potentials are conducted along myelinated nerves. We have developed
Externí odkaz:
https://doaj.org/article/03eead839e4f41d7bec3914e12952619
Autor:
William R. Reed, Joshua W. Little, Carla R. Lima, Robert E. Sorge, Ceren Yarar-Fisher, Mualla Eraslan, Christopher P. Hurt, Timothy J. Ness, Jianguo G. Gu, Daniel F. Martins, Peng Li
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
IntroductionLow back pain (LBP) is a complex and growing global health problem in need of more effective pain management strategies. Spinal mobilization (SM) is a non-pharmacological approach recommended by most clinical guidelines for LBP, but great
Externí odkaz:
https://doaj.org/article/aa63be6d2e6d4c5bbb442b0b64643834
Publikováno v:
Molecular Brain, Vol 11, Iss 1, Pp 1-9 (2018)
Abstract Leak K+ currents are mediated by two-pore domain K+ (K2P) channels and are involved in controlling neuronal excitability. Of 15 members of K2P channels cloned so far, TRAAK, TREK-1, and TREK-2 are temperature sensitive. In the present study,
Externí odkaz:
https://doaj.org/article/0fde696cfccc41e784d0198d43495a20
Publikováno v:
eNeuro; Nov/Dec2022, Vol. 9 Issue 6, p1-14, 14p
Autor:
Sotatsu Tonomura, Jianguo G. Gu
Publikováno v:
Journal of Neuroscience; 6/22/2022, Vol. 42 Issue 25, p4980-4994, 15p
Publikováno v:
Molecular pain. 18
Low threshold mechanoreceptors (LTMRs) are important for environmental exploration, social interaction, and tactile discrimination. Whisker hair follicles are mechanical sensory organs in non-primate mammals that are functionally equivalent to human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::95111faf51f8e3ed36959a942885c34f
https://pubmed.ncbi.nlm.nih.gov/35189758
https://pubmed.ncbi.nlm.nih.gov/35189758