Zobrazeno 1 - 10
of 87
pro vyhledávání: '"Jiangning Tan"'
Autor:
Ting-Yun Chen, Xiaoyun Li, Gillian C. Goobie, Ching-Hsia Hung, Tin-Kan Hung, Kyle Hamilton, Harinath Bahudhanapati, Jiangning Tan, Daniel J. Kass, Yingze Zhang
Publikováno v:
PLoS ONE, Vol 16, Iss 12 (2021)
Relaxin/insulin-like family peptide receptor 1 (RXFP1) mediates relaxin’s antifibrotic effects and has reduced expression in the lung and skin of patients with fibrotic interstitial lung disease (fILD) including idiopathic pulmonary fibrosis (IPF)
Externí odkaz:
https://doaj.org/article/a278f1d82dd0444cb398fea8e2fc65e6
Autor:
Ting‐Yun Chen, Xiaoyun Li, Ching‐Hsia Hung, Harinath Bahudhanapati, Jiangning Tan, Daniel J. Kass, Yingze Zhang
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 8, Iss 4, Pp n/a-n/a (2020)
Abstract Background Relaxin/relaxin family peptide receptor 1 (RXFP1) signaling is important for both normal physiology and disease. Strong preclinical evidence supports relaxin as a potent antifibrotic molecule. However, relaxin‐based therapy fail
Externí odkaz:
https://doaj.org/article/96e610b58a7c410ab9c85e4615ad23d7
Autor:
Jessica Bon, Rehan Kahloon, Yingze Zhang, Jianmin Xue, Carl R Fuhrman, Jiangning Tan, Mathew Burger, Daniel J Kass, Eva Csizmadia, Leo Otterbein, Divay Chandra, Arpit Bhargava, Joseph M Pilewski, G David Roodman, Frank C Sciurba, Steven R Duncan
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e105066 (2014)
Emphysema and osteoporosis are epidemiologically associated diseases of cigarette smokers. The causal mechanism(s) linking these illnesses is unknown. We hypothesized autoimmune responses may be involved in both disorders.To discover an antigen-speci
Externí odkaz:
https://doaj.org/article/8d3c8555d9664826b3dfa346585cf7b2
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e25725 (2011)
Matrix metalloproteinase 7 (MMP7), a metallohydrolase involved in the development of several cancers, is downregulated in the Apc(Min/+) colon cancer mouse model following sulindac treatment. To determine whether this effect is relevant to the human
Externí odkaz:
https://doaj.org/article/6fc241cda55c4c6c8c355248fdd57f63
Autor:
Eleanor Valenzi, Harinath Bahudhanapati, Jiangning Tan, Tracy Tabib, Daniel I. Sullivan, Mehdi Nouraie, John Sembrat, Li Fan, Kong Chen, Silvia Liu, Mauricio Rojas, Audrey Lafargue, Dean W. Felsher, Phuoc T. Tran, Daniel J. Kass, Robert Lafyatis
Publikováno v:
European Respiratory Journal. :2200474
BackgroundIn idiopathic pulmonary fibrosis (IPF) myofibroblasts are key effectors of fibrosis and architectural distortion by excessive deposition of extracellular matrix and their acquired contractile capacity. Single-cell RNA-sequencing (scRNA-seq)
Autor:
Mauricio Rojas, Jia Liu, Yutong Zhao, Jing Zhao, Xinxin Liao, Rama K. Mallampalli, Yanhui Li, Yingze Zhang, Daniel J. Kass, Jiangning Tan
Publikováno v:
Transl Res
Smad4 plays a central role in the regulation of extracellular matrix (ECM) protein expression and cell differentiation; however, the molecular regulation of Smad4 protein stability by a deubiquitinase has not been reported. In the current study, we r
Autor:
Jonathan K. Alder, Sonia Fung, Sharon E. Kim, Daniel J. Kass, Juan Wang, Y. Peter Di, Mauricio Rojas, Ting Yun Chen, Jing Zhao, Robert Lafyatis, Tracy Tabib, Xiaoyun Li, Claudette M. St. Croix, Yingze Zhang, John Sembrat, Sruti Shiva, Xia Yang, Jiangning Tan, Brandon Guo
Publikováno v:
FASEB J
Idiopathic pulmonary fibrosis (IPF) is characterized by altered epithelial cell phenotypes, which are associated with myofibroblast accumulation in the lung. Atypical alveolar epithelial cells in IPF express molecular markers of airway epithelium. Po
Autor:
Eleanor Valenzi, Harinath Bahudhanapati, Jiangning Tan, Tracy Tabib, Daniel I. Sullivan, John Sembrat, Li Fan, Kong Chen, Mauricio Rojas, Audrey Lafargue, Dean W. Felsher, Phuoc T. Tran, Daniel J. Kass, Robert Lafyatis
In idiopathic pulmonary fibrosis (IPF) myofibroblasts are key effectors of fibrosis and architectural distortion by excessive deposition of extracellular matrix and their acquired contractile capacity. Single-cell RNA-sequencing has precisely defined
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bad749531089ec90245d7441f0c287e0
https://doi.org/10.1101/2022.01.10.475117
https://doi.org/10.1101/2022.01.10.475117
Autor:
Xiaoyun Li, Harinath Bahudhanapati, Ting-Yun Chen, Ching Hsia Hung, Yingze Zhang, Gillian C Goobie, Kyle Hamilton, Jiangning Tan, Daniel J. Kass
Relaxin/insulin-like family peptide receptor 1 (RXFP1) mediates relaxin’s antifibrotic effects and has reduced expression in the lung and skin of patients with fibrotic interstitial lung disease (fILD) including idiopathic pulmonary fibrosis (IPF)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::66b0389e9ccdd7d3e6b66db2975d0d9a
https://doi.org/10.1101/2021.07.23.453556
https://doi.org/10.1101/2021.07.23.453556
Autor:
Taylor Adams, Chetan V. Jawale, Jonathan K. Alder, Antje Prasse, Xiaoyun Li, Harinath Bahudhanapati, Apel Rm, Mehdi Nouraie, John F. McDyer, Eleanor Valenzi, John Sembrat, Yanfu Zhang, Daniel I Sullivan, T. Chen, Naftali Kaminski, Partha S. Biswas, Tracy Tabib, Mauricio Rojas, Jiangning Tan, Benjamin Seeliger, Daniel J. Kass, Tedrow J, Robert Lafyatis, Wim A. Wuyts
Signaling via G protein-coupled receptors (GPCRs) can modulate levels of cyclic adenosine monophosphate (cAMP) and shape the functions of fibroblasts in idiopathic pulmonary fibrosis (IPF). We have identified Chemokine (C-X-C) Motif Ligand 6 (CXCL6)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::189d1c46aad652976002d27c485100b0
https://doi.org/10.1101/2021.06.22.449424
https://doi.org/10.1101/2021.06.22.449424