Zobrazeno 1 - 10
of 159
pro vyhledávání: '"Jiangning Chen"'
Autor:
Mingming Zhao, Xiaohui Cheng, Pingwen Shao, Yao Dong, Yongjie Wu, Lin Xiao, Zhiying Cui, Xuedi Sun, Chuancheng Gao, Jiangning Chen, Zhen Huang, Junfeng Zhang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract The CRISPR-Cas9 system offers substantial potential for cancer therapy by enabling precise manipulation of key genes involved in tumorigenesis and immune response. Despite its promise, the system faces critical challenges, including the pres
Externí odkaz:
https://doaj.org/article/778046d627d94e7193de279c87f1c995
Autor:
Yanyan He, Wenzhu Wang, Juan Jiang, Yuanxing Shen, Baoxi Wang, Jiangning Chen, Min Li, Haoxiang Xu
Publikováno v:
Heliyon, Vol 10, Iss 12, Pp e33146- (2024)
Background: Acne inversa (AI) is a refractory inflammatory skin disease, and TNF-α plays an important role in the pathogenesis of AI. By blocking TNF-α, infliximab (IFX) has been proven to be a promising method. Objectives: To explore the underlyin
Externí odkaz:
https://doaj.org/article/8703da0d830945c5ae9cb1e64f84b4de
Autor:
Qi Sun, Lin Xiao, Zhiying Cui, Yaping Yang, Junting Ma, Zhen Huang, Junfeng Zhang, Jiangning Chen
Publikováno v:
Chinese Medicine, Vol 17, Iss 1, Pp 1-13 (2022)
Abstract Background Immune checkpoint inhibitors that target programmed cell death protein 1 (PD-1) have obtained encouraging results, but a fraction of tumor patients failed to respond to anti-PD-1 treatment due to the existence of multiple immune s
Externí odkaz:
https://doaj.org/article/4bbc3859ce7f4b79bebf601177600532
Autor:
Yangyang Ye PhD, Qian Shi MA, Ting Yang MA, Fei Xie PhD, Xiang Zhang PhD, Bin Xu PhD, Jingwen Fang MA, Jiangning Chen PhD, Yujing Zhang PhD, Jing Li PhD
Publikováno v:
Technology in Cancer Research & Treatment, Vol 21 (2022)
Introduction: Tumor extracellular vesicles (EVs) and their relevance to various processes of tumor growth have been vigorously investigated over the past decade. However, obtaining direct evidence of spontaneous EV transfer in vivo remains challengin
Externí odkaz:
https://doaj.org/article/dd57179d78ec4e7d9d24aba02a305730
Autor:
Junqing Hu, Jinhao Xu, Mingyue Li, Yanping Zhang, Huaiqiang Yi, Jiangning Chen, Lei Dong, Junfeng Zhang, Zhen Huang
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 16, Iss , Pp 650-662 (2019)
Lymph nodes are important peripheral immune organs in which numerous important immune responses occur. During the process of lymphatic metastasis, lymph nodes are also sites through which tumor cells must pass. Therefore, it is essential to develop a
Externí odkaz:
https://doaj.org/article/d734dbcdbe0b40088064efeb440cff99
Autor:
Junqing Zhang, Rujing Wang, Zhou Jin, Hongyan Guo, Yi Liu, Yongjia Chang, Jiangning Chen, Mengya Li, Xiangyu Chen
Publikováno v:
Chemosensors, Vol 10, Iss 2, p 84 (2022)
The acquisition of nutrient data on a precise scale has played a vital role in nutrient management processes for soils. However, the lack of rapid precise and multi-index detection techniques for soil macronutrient contents hinders both rational fert
Externí odkaz:
https://doaj.org/article/c9cf47f642d846819e0f30016c81faef
Autor:
Xiaolong Tu, Yuanyuan Zhang, Xiuxiu Zheng, Jia Deng, Huanan Li, Zhiqian Kang, Zhipeng Cao, Zhen Huang, Zhi Ding, Lei Dong, Jiangning Chen, Yuhui Zang, Junfeng Zhang
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Abstract Hepatocyte death, as well as the following inflammatory and fibrogenic signaling cascades, is the key trigger of liver fibrosis. Here, we isolated hepatocytes from CCl4-induced fibrotic liver and found that hepatocyte lincRNA-p21 significant
Externí odkaz:
https://doaj.org/article/70ce8021694d4e498c58905a70720ed8
Autor:
Yanqing Liu, Uzair-ur-Rehman, Yu Guo, Hongwei Liang, Rongjie Cheng, Fei Yang, Yeting Hong, Chihao Zhao, Minghui Liu, Mengchao Yu, Xinyan Zhou, Kai Yin, Jiangning Chen, Junfeng Zhang, Chen-Yu Zhang, Feng Zhi, Xi Chen
Publikováno v:
Protein & Cell, Vol 7, Iss 10, Pp 722-734 (2016)
Abstract Programmed cell death 4 (PDCD4) is a RNA-binding protein that acts as a tumor suppressor in many cancer types, including colorectal cancer (CRC). During CRC carcinogenesis, PDCD4 protein levels remarkably decrease, but the underlying molecul
Externí odkaz:
https://doaj.org/article/12d53e612d0c4d65ab9e50dc3f8989c2
Gua Sha, a press-stroke treatment of the skin, boosts the immune response to intradermal vaccination
Autor:
Tingting Chen, Ninghua Liu, Jinxuan Liu, Xiaoying Zhang, Zhen Huang, Yuhui Zang, Jiangning Chen, Lei Dong, Junfeng Zhang, Zhi Ding
Publikováno v:
PeerJ, Vol 4, p e2451 (2016)
Objective The skin is an important immunological barrier of the body as well as an optimal route for vaccine administration. Gua Sha, which involves press-stroke treatment of the skin, is an effective folk therapy, widely accepted in East Asia, for v
Externí odkaz:
https://doaj.org/article/ee5c1a9b9cbb44aa8ab02cccdc64fc20
Publikováno v:
Chinese Chemical Letters. 33:314-319
Herein, the nanoscaled ATP-responsive upconversion metal-organic frameworks (UCMOFs) are aqueous-phase synthesized for co-delivery of therapeutic protein cytochrome c (Cyt c) and chemodrugs doxorubicin (DOX), achieving targeted combinational therapy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f25abe90e8bbfab9ff7a387a7e506b8
https://doi.org/10.1016/j.cclet.2021.07.007
https://doi.org/10.1016/j.cclet.2021.07.007