Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Jianglai Wu"'
Publikováno v:
Nature Photonics. 15:800-812
After over 30 years of advances, multiphoton microscopy (MPM) is now instrumental in a wide range of in vivo biological imaging applications. However, it has, until recently, remained not achievable or affordable to meet the unmet need for fast monit
Autor:
Justin S. J. Wong, Hayden K.-H. So, Jianglai Wu, Kevin K. Tsia, Gwinky G. K. Yip, Kelvin C. M. Lee, Michelle C. K. Lo, Tony T H D Le, Queenie T. K. Lai, Na Ji
Publikováno v:
Nature Protocols. 16:4227-4264
Laser scanning is used in advanced biological microscopy to deliver superior imaging contrast, resolution and sensitivity. However, it is challenging to scale up the scanning speed required for interrogating a large and heterogeneous population of bi
Autor:
Guanghan Meng, Jian Zhong, Qinrong Zhang, Justin S. J. Wong, Jianglai Wu, Kevin K. Tsia, Na Ji
Publikováno v:
Proceedings of the National Academy of Sciences. 119
Characterizing blood flow dynamics in vivo is critical to understanding the function of the vascular network under physiological and pathological conditions. Existing methods for hemodynamic imaging have insufficient spatial and temporal resolution t
Autor:
Donqging Shi, Michael Z. Lin, Jianglai Wu, Kevin K. Tsia, Mariya Chavarha, Na Ji, Yajie Liang, Shuo Chen, Ching-Lung Hsu, Stephen W Evans
Publikováno v:
Nature methods
Nature methods, vol 17, iss 3
Nature methods, vol 17, iss 3
Understanding information processing in the brain requires us to monitor neural activity in vivo at high spatiotemporal resolution. Using an ultrafast two-photon fluorescence microscope (2PFM) empowered by all-optical laser scanning, we imaged neural
Autor:
Dickson M. D. Siu, Queenie T. K. Lai, Kenneth K. Y. Wong, Hei Ming Lai, Jianglai Wu, Kevin K. Tsia, Yu-Xuan Ren, Wutian Wu
Publikováno v:
Light: Science & Applications, Vol 9, Iss 1, Pp 1-11 (2020)
Light, Science & Applications
Light, Science & Applications
Parallelized fluorescence imaging has been a long-standing pursuit that can address the unmet need for a comprehensive three-dimensional (3D) visualization of dynamical biological processes with minimal photodamage. However, the available approaches
Autor:
Queenie T K, Lai, Gwinky G K, Yip, Jianglai, Wu, Justin S J, Wong, Michelle C K, Lo, Kelvin C M, Lee, Tony T H D, Le, Hayden K H, So, Na, Ji, Kevin K, Tsia
Publikováno v:
Nature protocols. 16(9)
Laser scanning is used in advanced biological microscopy to deliver superior imaging contrast, resolution and sensitivity. However, it is challenging to scale up the scanning speed required for interrogating a large and heterogeneous population of bi
Publikováno v:
Nature Photonics. 16:87-87
Publikováno v:
High-Speed Biomedical Imaging and Spectroscopy IV.
Publikováno v:
Frontiers in Optics + Laser Science APS/DLS.
We demonstrate a new type of parallelized volumetric fluorescence imaging without any scanning mechanism, coined coded light-sheet array microscopy (CLAM), based upon reconfigurable generation of incoherent light-sheet array (>40 light-sheets) and mu
Flexible pulse-stretching for a swept source at 2.0 μm using free-space angular-chirp-enhanced delay
Publikováno v:
Optics letters. 43(1)
Dispersive pulse-stretching at 2.0 μm has long been hindered by the high intrinsic optical loss from conventional dispersive media. Here a flexible pulse-stretching technique at 2.0 μm is demonstrated over a broad bandwidth with large-scale dispers