Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Jianghong Yan"'
Autor:
Linqian Peng, Yunwei Chen, Yan Li, Panpan Feng, Yan Zheng, Yongjie Dong, Yunjing Yang, Ruiyu Wang, Ailing Li, Jianghong Yan, Feifei Shang, Ping Tang, Dewei Chen, Yuqi Gao, Wei Huang
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Pulmonary arterial hypertension (PAH) is an incurable disease with high mortality. Chemerin has been found to be associated with pulmonary hypertension (PH). However, the specific role of chemerin in mediating PH development remains unclear. This stu
Externí odkaz:
https://doaj.org/article/c6a07219afc24a6eadd3e939fb1ae292
Autor:
Ying Liu, Jianghong Yan, Yu Huang, Zhiheng Sun, Huijing Zhang, Lihaoyuan Fu, Xuwen Li, Yongri Jin
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 9 (2022)
Glutathione (GSH) is an important antioxidant and free radical scavenger that converts harmful toxins into harmless substances and excretes them out of the body. In the present study, we successfully prepared single-atom iron oxide-nanoparticle (Fe-N
Externí odkaz:
https://doaj.org/article/bcd7ee5baabf4c0b9211b229c62f17c4
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Parkinson’s disease (PD) is a common neurodegenerative disease in middle-aged and elderly individuals. At present, no effective drug has been developed to treat PD. Although a variety of drugs exist for the symptomatic treatment of PD, they all hav
Externí odkaz:
https://doaj.org/article/f8f08df8e69540029cbdc33615f0a3a1
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-13 (2019)
Abstract Background Tubeimoside-I (TBM), a plant-derived bioactive compound, shows antitumor activity in different tumors and can enhance the efficacy of chemotherapeutic agents. However, the detail mechanism underlying remains to be elucidated. Meth
Externí odkaz:
https://doaj.org/article/580e9b5e91f14929ba5c00f6f7eceb13
Autor:
Fei-Fei Shang, Li Luo, Jianghong Yan, Qiubo Yu, Yongzheng Guo, Yuchen Wen, Xiao-Li Min, Ling Jiang, Xiang He, Wei Liu
Publikováno v:
Redox Biology, Vol 34, Iss , Pp 101459- (2020)
Phosphatidylinositol-3,4,5-trisphosphate [PI(3,4,5)P3] is a phosphorylated derivative of phosphatidylinositol 4-phosphate [PI(4)P] and phosphatidylinositol 4,5-bisphosphate [PI(4,5)P2], which recruit and activate AKT in the plasma membrane (PM) to pr
Externí odkaz:
https://doaj.org/article/b48d2a50990e42bb8625369e035210c0
Autor:
Minghao Luo, Suxin Luo, Zhe Cheng, Xiyang Yang, Dingyi Lv, Xingbing Li, Yongzheng Guo, Chang Li, Jianghong Yan
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 126, Iss , Pp 110083- (2020)
Sepsis is a disease with high mortality rate worldwide and inducible nitric oxide (iNOS) induced vascular hyporeactivity plays a key role in it. There is no effective drug to treat vascular hyporeactivity specifically. Tubeimoside I (TBM) is a triter
Externí odkaz:
https://doaj.org/article/14cf518fadb24a6fac321a71ca904f6e
Publikováno v:
Virology Journal, Vol 15, Iss 1, Pp 1-8 (2018)
Abstract Background Rabies is a fatal disease that is preventable when post exposure prophylaxis (PEP) is administered in a timely fashion. CpG oligodeoxynucleotides (ODNs) can trigger cells that express Toll-like receptor 9, and their immunopotentia
Externí odkaz:
https://doaj.org/article/2ce656929b0a4596b208f1e653877ab7
Autor:
Jianghong Yan, Ting Du, Wan Zhao, Thomas Hartmann, Hua Lu, Yang Lü, Haomiao Ouyang, Xuejun Jiang, Lei Sun, Cheng Jin
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e59013 (2013)
Previously, it has been shown that GPI proteins are required for cell wall synthesis and organization in Aspergillus fumigatus, a human opportunistic pathogen causing life-threatening invasive aspergillosis (IA) in immunocompromised patients. Blockin
Externí odkaz:
https://doaj.org/article/50f9b7111bf649a68adc71d1550ef7ce
Autor:
Dexin Zhao, Jianghong Yan, Xiaolei Shi, Zhiheng Sun, Huili Xie, Bingzi Wang, Yongri Jin, Xuwen Li
Publikováno v:
Phytochemistry Letters. 53:202-210
Publikováno v:
Metabolic Brain Disease. 37:1977-1987
Cerebral ischemia causes hypoxic injury and inflammation, and brain microvascular endothelial cells (BMVECs) dysfunction is an initial stage of blood-brain barrier disruption. Endothelial cells secrete extracellular vesicles (EVs) that are involved i