Zobrazeno 1 - 10
of 113
pro vyhledávání: '"JiangWen Zhang"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Endometrial cancer (EC), one of the most prevalent carcinomas in females, is associated with increasing mortality. We identified the CHD4 R975H mutation as a high-frequency occurrence in EC patients through a comprehensive survey of EC datab
Externí odkaz:
https://doaj.org/article/57014df91da340b1a43ea1fbf7d3160b
Publikováno v:
Photonics, Vol 11, Iss 3, p 212 (2024)
With the growing trend in the information industry, silicon photonics technology has been explored in both academia and industry and utilized for high-bandwidth data transmission. Thanks to the benefits of silicon, such as high refractive index contr
Externí odkaz:
https://doaj.org/article/08f2d59d4d2d4c43899e194b5f516574
Autor:
Haibo Qiu, Xu Zhang, Jiali Qi, Jiangwen Zhang, Yin Tong, Lei Li, Li Fu, Yan-Ru Qin, Xinyuan Guan, Liyi Zhang
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-24 (2022)
Abstract Background Cancer-associated fibroblast (CAF) is an ideal target for cancer treatment. Recent studies have focused on eliminating CAFs and their effects by targeting their markers or blocking individual CAF-secreted factors. However, these s
Externí odkaz:
https://doaj.org/article/f4bdca23331b499ba9d71306ec3ed6fc
Autor:
Sally K. Y. To, Maggie K. S. Tang, Yin Tong, Jiangwen Zhang, Karen K. L. Chan, Philip P. C. Ip, Jue Shi, Alice S. T. Wong
Publikováno v:
Advanced Science, Vol 9, Iss 16, Pp n/a-n/a (2022)
Abstract Tumor heterogeneity plays a key role in cancer relapse and metastasis, however, the distinct cellular behaviors and kinetics of interactions among different cancer cell subclones and the tumor microenvironment are poorly understood. By profi
Externí odkaz:
https://doaj.org/article/f8efb9df80894269b762bc0a6342de94
Autor:
Shan-Shan Li, Carman K. M. Ip, Matthew Y. H. Tang, Maggie K. S. Tang, Yin Tong, Jiangwen Zhang, Ayon Ahmed Hassan, Abby S. C. Mak, Susan Yung, Tak-Mao Chan, Philip P. Ip, Cheuk Lun Lee, Philip C. N. Chiu, Leo Tsz On Lee, Hung-Cheng Lai, Jin-Zhang Zeng, Ho Cheung Shum, Alice S. T. Wong
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Tumor cell in the peritoneum are often exposed to shear forces generated by ascitic flow during metastasis. Here, the authors show that metastatic cancer stem cells tether more and roll slower than the non-metastatic counterparts, and that sialyl-Lew
Externí odkaz:
https://doaj.org/article/adfaf653b8994433a83662d8754dca91
Autor:
Yin Tong, Jianlong Sun, Chi Fat Wong, Qingzheng Kang, Beibei Ru, Ching Ngar Wong, April Sheila Chan, Suet Yi Leung, Jiangwen Zhang
Publikováno v:
Genome Biology, Vol 19, Iss 1, Pp 1-17 (2018)
Abstract Aberrant promoter methylation is a common mechanism for tumor suppressor inactivation in cancer. We develop a set of tools to identify genome-wide DNA methylation in distal regions with causal effect on tumorigenesis called MICMIC. Many pred
Externí odkaz:
https://doaj.org/article/8a6dcb37f9db48b38bc01aec0c1c0785
Autor:
Ming Chen, Lixin Wan, Jiangwen Zhang, Jinfang Zhang, Lourdes Mendez, John G. Clohessy, Kelsey Berry, Joshua Victor, Qing Yin, Yuan Zhu, Wenyi Wei, Pier Paolo Pandolfi
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
Alterations in the MAPK pathway are common in cancers, yet mutations are rarely found in patients. Here the authors find genomic amplifications of the PPP1CA gene in advanced and metastatic prostate cancer and identify a role for this phosphatase in
Externí odkaz:
https://doaj.org/article/3c35271d6beb405c951ac4056c1c2de6
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
In a previous study, incorporation of high exopolysaccharide (EPS) producing dairy starter bacterium Streptococcus thermophilus ASCC 1275 was found to improve functionality of low fat mozzarella cheese and yogurt. This bacterium in its eps gene clust
Externí odkaz:
https://doaj.org/article/78c3053e5ba0402fa4d2fa9585cd6da8
Autor:
Alberto Toso, Ajinkya Revandkar, Diletta Di Mitri, Ilaria Guccini, Michele Proietti, Manuela Sarti, Sandra Pinton, Jiangwen Zhang, Madhuri Kalathur, Gianluca Civenni, David Jarrossay, Erica Montani, Camilla Marini, Ramon Garcia-Escudero, Eugenio Scanziani, Fabio Grassi, Pier Paolo Pandolfi, Carlo V. Catapano, Andrea Alimonti
Publikováno v:
Cell Reports, Vol 9, Iss 1, Pp 75-89 (2014)
Summary: Prosenescence therapy has recently emerged as a novel therapeutic approach for treating cancer. However, this concept is challenged by conflicting evidence showing that the senescence-associated secretory phenotype (SASP) of senescent tumor
Externí odkaz:
https://doaj.org/article/c94fd7136b0645978c258289d1966502
Autor:
Biliana Lesic, François Lépine, Eric Déziel, Jiangwen Zhang, Qunhao Zhang, Katie Padfield, Marie-Hélène Castonguay, Sylvain Milot, Scott Stachel, A Aria Tzika, Ronald G Tompkins, Laurence G Rahme
Publikováno v:
PLoS Pathogens, Vol 3, Iss 9, Pp 1229-1239 (2007)
Long-term antibiotic use generates pan-resistant super pathogens. Anti-infective compounds that selectively disrupt virulence pathways without affecting cell viability may be used to efficiently combat infections caused by these pathogens. A candidat
Externí odkaz:
https://doaj.org/article/e152aa1dae1e4fd2921f7f4e7f1f8b39