Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Jiang-jie Duan"'
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 39, Iss 1 (2024)
Metabolic abnormalities are an important feature of tumours. The glutamine-arginine-proline axis is an important node of cancer metabolism and plays a major role in amino acid metabolism. This axis also acts as a scaffold for the synthesis of other n
Externí odkaz:
https://doaj.org/article/88d998c2316f44619b279444c3ce413a
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 38, Iss 1 (2023)
High aldehyde dehydrogenase (ALDH) activity is a metabolic feature of adult stem cells and various cancer stem cells (CSCs). The ALDEFLUOR system is currently the most commonly used method for evaluating ALDH enzyme activity in viable cells. This sys
Externí odkaz:
https://doaj.org/article/15390384d2264bcd941d4fe88a73f588
Publikováno v:
Breast Cancer Research, Vol 22, Iss 1, Pp 1-13 (2020)
Abstract Triple-negative breast cancer (TNBC), a specific subtype of breast cancer that does not express estrogen receptor (ER), progesterone receptor (PR), or human epidermal growth factor receptor 2 (HER-2), has clinical features that include high
Externí odkaz:
https://doaj.org/article/be95e0ec751e47caba9c7a2a68721490
Autor:
Jiang-Jie, Duan, Di, Wang, Jiao, Cai, Jun-Jie, Chen, Xiao-Xia, Zheng, Tian-Qing, Chen, Jun, Wang, Xiao, Zhang, Qing-Kai, Yang, Shi-Cang, Yu
Publikováno v:
Cancer Letters. 536:215662
Metastasis is the leading cause of death for patients with colorectal cancer (CRC). The development of therapeutic regimens that selectively inhibit the biological processes involved in CRC cell dissemination is important. We used multiple Affymetrix
Publikováno v:
Breast Cancer Research : BCR
Breast Cancer Research, Vol 22, Iss 1, Pp 1-13 (2020)
Breast Cancer Research, Vol 22, Iss 1, Pp 1-13 (2020)
Triple-negative breast cancer (TNBC), a specific subtype of breast cancer that does not express estrogen receptor (ER), progesterone receptor (PR), or human epidermal growth factor receptor 2 (HER-2), has clinical features that include high invasiven
Autor:
Ting-Ting Huang, Tao Tang, Jiao Cai, Hua-rong Zhang, Xiu-Wu Bian, Yong-Jun Yang, Jing Lv, Qian Wen, Jing Yang, Xue-Mei Liao, Shi-cang Yu, Jun Wang, Di Wang, Yu-Feng Guo, Xun-Zhou Liu, Ze-Yu Yang, Xian-yan Yang, Feng Wu, Jiang-Jie Duan, Lin Li
Publikováno v:
Science Translational Medicine. 12
MYCN-amplified neuroblastoma (NB) is characterized by poor prognosis, and directly targeting MYCN has proven challenging. Here, we showed that aldehyde dehydrogenase family 18 member A1 (ALDH18A1) exerts profound impacts on the proliferation, self-re
Autor:
Yu-Feng, Guo, Jiang-Jie, Duan, Jun, Wang, Lin, Li, Di, Wang, Xun-Zhou, Liu, Jing, Yang, Hua-Rong, Zhang, Jing, Lv, Yong-Jun, Yang, Ze-Yu, Yang, Jiao, Cai, Xue-Mei, Liao, Tao, Tang, Ting-Ting, Huang, Feng, Wu, Xian-Yan, Yang, Qian, Wen, Xiu-Wu, Bian, Shi-Cang, Yu
Publikováno v:
Science translational medicine. 12(531)
Publikováno v:
International Journal of Cancer. 139:965-975
Metabolism reprogramming has been linked with the initiation, metastasis, and recurrence of cancer. The aldehyde dehydrogenase (ALDH) family is the most important enzyme system for aldehyde metabolism. The human ALDH family is composed of 19 members.
Autor:
Shi-cang Yu, Yu-Feng Guo, Lin Li, Jing-Ya Kuang, Jun Wang, Ying Chen, Xiu-Wu Bian, Jiang-jie Duan, Xiao‐Li He
Publikováno v:
Cancer Science
Although the deregulation of epidermal growth factor receptor (EGFR) is one of the most common molecular mechanisms of glioblastoma (GBM) pathogenesis, the efficacy of anti-EGFR therapy is limited. Additionally, response to anti-EGFR therapy is not s
Autor:
Xue-Mei Liao, Yu-Feng Guo, Xia Zhang, Shi-cang Yu, Hao Wu, Hualiang Xiao, Lin Li, Yu Shi, Liang Yi, Qing-Kai Yang, Jun Wang, Yan-Qi Zhang, Ze-Yu Yang, Tao Jiang, Xiu-Wu Bian, Xiaojun Yang, Sheng-Qing Lv, Jiao Cai, Li Yin, Sen-Lin Xu, Jiang-Jie Duan, Jing-Na Zhang
Publikováno v:
Nature neuroscience. 22(1)
Early invasive growth along specific anatomical structures, especially the white matter tract, is regarded as one of the main causes of poor therapeutic outcome of people with gliomas. We show that some glioma stem cells (GSCs) are preferentially loc