Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Jiang-Rong Ou"'
Publikováno v:
BioMed Research International. 2014, Vol. 2014, p1-7. 7p.
Autor:
Dan Miao, Zhong-Chen Wu, Lan Tan, Wei Zhang, Jiang-Rong Ou, Jin-Tai Yu, Wei-Zhen Cui, Yan Tian
Publikováno v:
Current Alzheimer Research. 9:458-466
Toll-like receptor 4 (TLR4) represents a reasonable functional and positional candidate gene for Alzheimer's disease (AD) as it is located within the previous identified linkage region of AD on chromosome 9q, and functionally is involved in the micro
Publikováno v:
Clinical Neurology and Neurosurgery. 112:320-323
Objectives To investigate influences of the functional polymorphisms of Cytochrome P450 isozymes 2A6 (CYP2A6), 2B6 (CYP2B6), and 2C9 (CYP2C9) on pharmacokinetics of VPA in vivo. Patients and methods In the study, we analyzed the genotypes of CYP2A6,
Publikováno v:
BioMed Research International, Vol 2014 (2014)
BioMed Research International
BioMed Research International
Alzheimer’s disease (AD) is the first most common neurodegenerative disease. Despite a large amount of research, the pathogenetic mechanism of AD has not yet been clarified. The two hallmarks of the pathology of AD are the extracellular senile plaq
Publikováno v:
Neuroscience letters. 560
Recently, two large genome-wide association studies (GWASs) have identified several variants at 12q14 and 12q24 which are associated with hippocampal volume, one of the most important biological markers of Alzheimer's disease (AD). The strongest asso
Publikováno v:
Journal of the neurological sciences. 335(1-2)
An expanded hexanucleotide repeat in the chromosome 9 open reading frame 72 (C9ORF72), on chromosome 9p21, has recently been identified as a major cause of familial frontotemporal dementia (FTD). The neuropathology and clinical characteristics associ
Publikováno v:
Brain research. 1210
Increasing evidence indicates that the beta2-adrenergic receptor (beta2-AR) may play an important role in Alzheimer's disease (AD). We investigated the effect of two polymorphisms in the beta2-AR gene: Gly16Arg and Gln27Glu for the risk of sporadic L
Publikováno v:
Neurobiology of Aging. 32:1924.e1-1924.e3
Toll-like receptor 2 (TLR2) represents a reasonable functional and positional candidate gene for Alzheimer's disease (AD) as it is located under the linkage region of AD on chromosome 4q, and is functionally involved in the microglia-mediated inflamm