Zobrazeno 1 - 10
of 718
pro vyhledávání: '"Jiang Gu"'
Autor:
Weifeng Zhang, Jirui Li, Fengshan Xie, Liting Zeng, Liangli Hong, Penghao Li, Xiaomiao Yan, Jingliang Xu, Meina Du, Jiongzhi Hong, Dingrong Yi, Jiahao Xie, Jiang Gu
Publikováno v:
Engineering in Life Sciences, Vol 24, Iss 11, Pp n/a-n/a (2024)
ABSTRACT Immunohistochemistry (IHC) is a widely used technique in diagnostic pathology and biomedical research, but there is still a need to shorten the operation process and reduce the cost of antibodies. This study aims to assess a novel IHC techni
Externí odkaz:
https://doaj.org/article/cc84ccb64a5242b5bf702cceee0b3e2d
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-18 (2024)
Abstract Erectile dysfunction (ED) is a common and difficult to treat disease, and has a high incidence rate worldwide. As a marker of vascular disease, ED usually occurs in cardiovascular disease, 2–5 years prior to cardiovascular disease events.
Externí odkaz:
https://doaj.org/article/af3c713d17b84f9f981e25e7ec020ccc
Fc–Fc interactions and immune inhibitory effects of IgG4: implications for anti-PD-1 immunotherapies
Autor:
Hui Wang, Yu Xia, Meng Su, Baiyong Li, Xingxing Chen, Weifeng Zhang, Xueling Chen, Jirui Li, Xiaomiao Yan, Han Zha, Xiaonan Ma, Chanyuan Zhao, Liangli Hong, Penghao Li, Yanyu Ling, Wenhui Zhao, Tianjing Zheng, Jiang Gu
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 6 (2024)
Background The majority of anti-programmed cell-death 1 (PD-1) monoclonal antibodies (mAbs) use S228P mutation IgG4 as the structural basis to avoid the activation of immune cells or complement. However, little attention has been paid to the Fc–Fc
Externí odkaz:
https://doaj.org/article/025616ada6fc462891c673619d9ec90d
Autor:
Tao Li, Yi-Ting Jiang, Xin-Zhu Qi, Peng Chen, Jun-Hao Zhang, Fu Luo, Jun Qiao, Jiang Gu, Guang-Shi Du, Qiang Wang
Publikováno v:
Asian Journal of Andrology, Vol 26, Iss 2, Pp 205-211 (2024)
In order to explore the impact of circadian disturbance on erectile function, we randomly divided 24 adult male rats into groups of control (light on at 8:00 a.m. and off at 8:00 p.m.), dark/dark (DD; constant dark), light/light (LL; constant light),
Externí odkaz:
https://doaj.org/article/bee401b7d05e427bb5c6c474ded0008f
Autor:
Xiaolan Lin, Tian Guan, Yien Xu, Yun Li, Yanchun Lin, Shaobin Chen, Yuping Chen, Xiaolong Wei, Dongsheng Li, Yukun Cui, Yan Lin, Pingnan Sun, Jianmin Guo, Congzhu Li, Jiang Gu, Wei Yang, Haoyu Zeng, Changchun Ma
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionChimeric antigen receptor natural killer (CAR-NK) cells have been found to be successful in treating hematologic malignancies and present potential for usage in solid tumors.MethodsIn this study, we created CD276-targeted CAR-expressing N
Externí odkaz:
https://doaj.org/article/ff8feaad2b98496c8e741cf63e21a294
Autor:
Xiaolan Lin, Tian Guan, Yun Li, Yanchun Lin, Guowei Huang, Yan Lin, Pingnan Sun, Congzhu Li, Jiang Gu, Haoyu Zeng, Changchun Ma
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionThe clinical efficacy of CAR-NK cells against CD19-expressing blood cancers has been demonstrated, and they have shown potential for treating solid tumors as well. However, the efficacy of CAR-NK cells for treating human oral tongue squam
Externí odkaz:
https://doaj.org/article/2f4acbd60e284a1682c5172ca3fe7a7d
Autor:
Xueyang Fan, Rui Ma, Changjuan Yue, Jiabin Liu, Bisong Yue, Wanjing Yang, Yunli Li, Jiang Gu, James E. Ayala, Daniel E. Bunker, Xia Yan, Dunwu Qi, Xiaoyan Su, Lin Li, Dongsheng Zhang, Hongwen Zhang, Zhisong Yang, Rong Hou, Songrui Liu
Publikováno v:
International Journal for Parasitology: Parasites and Wildlife, Vol 20, Iss , Pp 162-169 (2023)
Ticks and tick-borne diseases have negative impacts on the health of wild animals including endangered and vulnerable species. The giant panda (Ailuropoda melanoleuca), a vulnerable and iconic flagship species, is threatened by tick infestation as we
Externí odkaz:
https://doaj.org/article/c2098f211e3746fe99e24334d7b6b80f
Autor:
Chen Gao, Yin Chen, Xin Cheng, Yi Zhang, Yueyue Zhang, Ying Wang, Zhiyuan Cui, Yaling Liao, Ping Luo, Weihui Wu, Cheng Wang, Hao Zeng, Quanming Zou, Jiang Gu
Publikováno v:
Journal of Nanobiotechnology, Vol 20, Iss 1, Pp 1-14 (2022)
Abstract The increasing prevalence of antibiotic resistance by Pseudomonas aeruginosa (PA) raises an urgent need for an effective vaccine. The outer membrane proteins of PA, especially those that are upregulated during infection, are ideal vaccine ta
Externí odkaz:
https://doaj.org/article/8f11288631ff4a7ea5b80b9a788a29a7
Autor:
Yuhang Li, Ruixue Pu, Yi Zhang, Yiwen Zhang, Yujie Wei, Sheng Zeng, Chen Gao, Ying Wang, Daijiajia Yin, Yueyue Zhang, Jiqing Wan, Quanming Zou, Jiang Gu
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionSerious infections of Pseudomonas aeruginosa (PA) in hospitals and the emergence and increase of multidrug resistance have raised an urgent need for effective vaccines. However, no vaccine has been approved to date. One possible reason fo
Externí odkaz:
https://doaj.org/article/8882b548d04e40beb0d9a6ce3f81d9dd
Autor:
Weifeng Zhang, Yan Quan, Xiaonan Ma, Liting Zeng, Jirui Li, Shuqi Chen, Meng Su, Liangli Hong, Penghao Li, Hui Wang, Qian Xu, Chanyuan Zhao, Xiaoqing Zhu, Yiqun Geng, Xiaomiao Yan, Zheng Fang, Muwang Chen, Dongping Tian, Min Su, Xueling Chen, Jiang Gu
Publikováno v:
Redox Biology, Vol 60, Iss , Pp 102608- (2023)
Background: We recently reported a novel IgG4-centered immune evasion mechanism in cancer, and this was achieved mostly through the Fc-Fc reaction of increased IgG4 to cancer-bound IgG in cancer microenvironment. The mechanism was suggested to be rel
Externí odkaz:
https://doaj.org/article/9331938a39144b638c82e786770b693c