Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Jiang‑Rui Zhou"'
Autor:
Jiang-Rui Zhou, Chun-Lei Jiang, Ding-Ya Sun, Xia Wang, Xiao-Liang Shen, Teng-Yun Wu, Lei Liu, Yi Zhang, Yun-Xia Wang, Yun-Li Peng, Yun-Zi Liu, Ai-Jun Huang
Publikováno v:
CNS Neuroscience & Therapeutics. 20:119-124
Summary Aims The NLRP3 inflammasome is a cytoplasmic multiprotein complex of the innate immune system that regulates the cleavage of interleukin-1β and interleukin-18 precursors. It can detect a wide range of danger signals and trigger a series of i
Autor:
Chun-Lei Jiang, Wei Peng, Teng-Yun Wu, Jiang-Rui Zhou, Hong Gong, Ting Zhang, Yuan-Yuan Yang, Yun-Xia Wang, Wen-Jun Su, Yi Zhang, Yong-Jie Lian
Publikováno v:
Brain, behavior, and immunity. 59
High mobility group box 1 (HMGB1) has been implicated as a key factor in several neuroinflammatory conditions. Our previous study suggested that the release of central HMGB1 acts as a late-phase mediator in lipopolysaccharide (LPS)-induced depression
Autor:
Jiang-Rui Zhou, Jing Zaiping, Zhen Li, Chun-Lei Jiang, Jian Zhou, Yi-Zhang Chen, Lei Liu, Chun-Quan Sheng, Yan Wang, Min Li
Publikováno v:
Cellular and Molecular Life Sciences. 68:1405-1414
Glucocorticoids (GCs) are routinely believed to take effect through genomic mechanisms, which are also largely responsible for GCs' side effects. Beneficial non-genomic effects of GCs have been reported as being independent of the genomic pathway. He
Autor:
Jiang‑Rui Zhou, Chun‑Lei Jiang, Wen‑Lei Shi, Ting Zhang, Yun‑Li Peng, Yong‑Ji Yang, Jeffrey G. Tasker, Chao‑Yu Miao
Publikováno v:
Molecular medicine reports. 7(2)
The aim of the present study was to identify the rapid effect of dexamethasone (Dex) on norepinephrine (NE)‑mediated contraction of vascular smooth muscle cells (VSMCs) and to establish the underlying mechanism(s). Rat VSMCs were preincubated with
Autor:
Chun-Lei Jiang, Yue Wang, Jiang-Rui Zhou, Fei Long, Hai-Wen Sun, Yi-Zhang Chen, Yun-Zi Liu, Lei Liu
Publikováno v:
Inflammation research : official journal of the European Histamine Research Society ... [et al.]. 54(1)
Glucocorticoids acting as anti-inflammatory or immunosuppressive drugs have been shown to exert most of their effects genomically. Recent findings suggest that non-genomic activity might be relatively more important in mediating the therapeutic effec