Structure of LARP7 Protein p65–telomerase RNA Complex in Telomerase Revealed by Cryo-EM and NMR

Autor: Wang, Yaqiang, He, Yao, Wang, Yanjiao, Yang, Yuan, Singh, Mahavir, Eichhorn, Catherine D., Cheng, Xinyi, Jiang, Yi Xiao, Zhou, Z. Hong, Feigon, Juli

Publikováno v: In Journal of Molecular Biology 1 June 2023 435(11)

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Amyloid fibrils in disease FTLD-TDP are composed of TMEM106B not TDP-43

Autor: Jiang, Yi Xiao, Cao, Qin, Sawaya, Michael R., Abskharon, Romany, Ge, Peng, DeTure, Michael, Dickson, Dennis W., Fu, Janine Y., Ogorzalek Loo, Rachel R., Loo, Joseph A., Eisenberg, David S.

Publikováno v: Nature

Frontotemporal lobar degeneration (FTLD) is the third most common neurodegenerative condition, following only Alzheimer’s and Parkinson’s diseases(1). FTLD typically presents in 45–64-year-olds with behavioral changes or progressive decline of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::46b78badf267e0e7c74092aa5902d924
https://europepmc.org/articles/PMC9844993/

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

How short peptides can disassemble ultra-stable tau fibrils extracted from Alzheimer's disease brain by a strain-relief mechanism.

Autor: Eisenberg D; UCLA., Hou K; University of California, Los Angeles., Ge P; University of California, Los Angeles., Sawaya M; University of California Los Angeles., Dolinsky J; University of California, Los Angeles., Yang Y; University of California Los Angeles., Jiang YX; University of California, Los Angeles., Lutter L; University of California, Los Angeles., Boyer D; University of California Los Angeles., Cheng X; UCLA., Pi J; University of California, Los Angeles., Zhang J; University of California, Los Angeles., Lu J; University of California, Los Angeles., Yang S; Janelia Research Campus, Howard Hughes Medical Institute., Yu Z; Howard Hughes Medical Institute., Feigon J; University of California, Los Angeles.

Publikováno v: Research square [Res Sq] 2024 May 08. Date of Electronic Publication: 2024 May 08.