Role of the WASP and WAVE family proteins in breast cancer invasion and metastasis

Autor: Frugtniet B, Jiang WG, Martin TA

Publikováno v: Breast Cancer: Targets and Therapy, Vol 2015, Iss default, Pp 99-109 (2015)

Bethan Frugtniet, Wen G Jiang, Tracey A Martin Cardiff-China Medical Research Collaborative, Cardiff University School of Medicine, Cardiff University, Cardiff, UKAbstract: The Wiskott–Aldrich syndrome protein (WASP) and WASP family verprolin-homol

Externí odkaz: https://doaj.org/article/870772f740544e57bdea345cd3e622d0

The mRNA expression of SETD2 in human breast cancer: correlation with clinico-pathological parameters

Autor: Al Sarakbi W, Sasi W, Jiang WG, Roberts T, Newbold RF, Mokbel K

Publikováno v: BMC Cancer, Vol 9, Iss 1, p 290 (2009)

Abstract Background SET domain containing protein 2 (SETD2) is a histone methyltransferase that is involved in transcriptional elongation. There is evidence that SETD2 interacts with p53 and selectively regulates its downstream genes. Therefore, it c

Externí odkaz: https://doaj.org/article/dc1b5b5a3eb24220928b57c92d73a9d4

Designing a broad-spectrum integrative approach for cancer prevention and treatment

Autor: Block, KI, Gyllenhaal, C, Lowe, L, Amedei, A, Ruhul Amin, ARM, Amin, A, Aquilano, K, Arbiser, J, Arreola, A, Arzumanyan, A, Salman Ashraf, S, Azmi, AS, Benencia, F, Bhakta, D, Bilsland, A, Bishayee, A, Blain, SW, Block, PB, Boosani, CS, Carey, TE, Carnero, A, Carotenuto, M, Casey, SC, Chakrabarti, M, Chaturvedi, R, Chen, GZ, Chen, H, Chen, S, Chen, YC, Choi, BK, Ciriolo, MR, Coley, HM, Collins, AR, Connell, M, Crawford, S, Curran, CS, Dabrosin, C, Damia, G, Dasgupta, S, DeBerardinis, RJ, Decker, WK, Dhawan, P, Diehl, AME, Dong, JT, Dou, QP, Drewa, JE, Elkord, E, El-Rayes, B, Feitelson, MA, Felsheru, DW, Ferguson, LR, Fimognari, C, Firestone, GL, Frezza, C, Fujii, H, Fuster, MM, Generali, D, Georgakilas, AG, Gieseler, F, Gilbertson, M, Green, MF, Grue, B, Guhal, G, Halicka, D, Helferich, WG, Heneberg, P, Hentosh, P, Hirschey, MD, Hofseth, LJ, Holcombe, RF, Honoki, K, Hsu, HY, Huang, GS, Jensen, LD, Jiang, WG, Jones, LW, Karpowicz, PA, Keith, WN, Kerkar, SP, Khan, GN, Khatami, M, Ko, YH, Kucuk, O, Kulathinal, RJ, Kumar, NB, Kwon, BS, Leb, A, Leab, MA, Lee, HY, Lichtor, T, Lin, LT, Locasale, JW

Publikováno v: Block, KI; Gyllenhaal, C; Lowe, L; Amedei, A; Ruhul Amin, ARM; Amin, A; et al.(2015). Designing a broad-spectrum integrative approach for cancer prevention and treatment. Seminars in Cancer Biology, 35, S276-S304. doi: 10.1016/j.semcancer.2015.09.007. Lawrence Berkeley National Laboratory: Retrieved from: http://www.escholarship.org/uc/item/62d7n4g9

© 2015 The Authors. Targeted therapies and the consequent adoption of "personalized" oncology have achieved notablesuccesses in some cancers; however, significant problems remain with this approach. Many targetedtherapies are highly toxic, costs are

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::b7b7b2fad02d7325bc39873f0ca1f301
http://www.escholarship.org/uc/item/62d7n4g9

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