Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Jianfeng Shu"'
MDM2 provides TOP2 poison resistance by promoting proteolysis of TOP2βcc in a p53-independent manner
Publikováno v:
Cell Death and Disease, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract DNA topoisomerase II (TOP2) is an enzyme that performs a critical function in manipulating DNA topology during replication, transcription, and chromosomal compaction by forming a vital intermediate known as the TOP2-DNA cleavage complex (TOP
Externí odkaz:
https://doaj.org/article/9df07424b7e843ff9c5b7c18396498a4
Publikováno v:
Cell Death and Disease, Vol 15, Iss 5, Pp 1-2 (2024)
Externí odkaz:
https://doaj.org/article/e2cd4e04991f44909ea9625bc374e7e4
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/2ce8517f9cfe4b63bfdd93c105d156ec
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-3 (2023)
Externí odkaz:
https://doaj.org/article/f2ee02595e7d475fa6bafc5f0a103a4a
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Type II topoisomerases (TOP2) poisons represent one class of the most successful and widely prescribed chemotherapeutics, which is frontline therapy for a myriad of systemic cancers and solid tumors, including lymphomas, leukemias, and lung
Externí odkaz:
https://doaj.org/article/292868a365b34e8bbfbcb229d00b7730
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundLung adenocarcinoma (LUAD) as a frequent type of lung cancer has a 5-year overall survival rate of lower than 20% among patients with advanced lung cancer. This study aims to construct a risk model to guide immunotherapy in LUAD patients ef
Externí odkaz:
https://doaj.org/article/3a76079294da4f0bb8493cb2243e20e2
Publikováno v:
Cell Reports, Vol 30, Iss 2, Pp 497-509.e4 (2020)
Summary: The tumor suppressor p53 plays a critical role in integrating a wide variety of stress responses. Therefore, p53 levels are precisely regulated by multiple ubiquitin ligases. In this study, we report that FBXW7, a substrate recognition compo
Externí odkaz:
https://doaj.org/article/065c84736395404caebc8dd0afd09e42
Publikováno v:
Journal of Proteome Research; 8/2/2024, Vol. 23 Issue 8, p3674-3681, 8p
Publikováno v:
Traitement du Signal. Feb2022, Vol. 39 Issue 1, p355-362. 8p.
Publikováno v:
Evidence-based Complementary and Alternative Medicine : eCAM
Evidence-Based Complementary and Alternative Medicine, Vol 2021 (2021)
Evidence-Based Complementary and Alternative Medicine, Vol 2021 (2021)
In this prospective study, we used the random number table method to equally divide 141 patients with chronic nonspecific low back pain (CNLBP) who met the inclusion criteria into 3 groups. One group who received massage manipulation therapy was reco