Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Jianfeng Ge"'
Autor:
Miaomiao Li, Xusheng Wang, Rosalind Kieran, Zheng Wei Sun, Yubin Gong, Hongzhao Lei, Bin Sun, Li Xiao, Yanlin Wang, Song Wang, Zhiyu Li, Luying Wang, Renrong Lv, Feng Xue, Jianfeng Ge, Changxian Dong, Ran Huo
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
BackgroundKaposiform hemangioendothelioma (KHE) is a rare vascular tumor with a high risk of mortality. Few studies with large samples of KHE have been reported. KHE may develop into the Kasabach–Merritt phenomenon (KMP), which is characterized by
Externí odkaz:
https://doaj.org/article/20a4b113b67147c7a98d51d09e2cf9bd
Autor:
Ludovic Wesolowski, Jianfeng Ge, Leticia Castillon, Debora Sesia, Anna Dyas, Shoko Hirosue, Veronica Caraffini, Anne Y. Warren, Paulo Rodrigues, Giovanni Ciriello, Saroor A. Patel, Sakari Vanharanta
Publikováno v:
iScience, Vol 26, Iss 8, Pp 107360- (2023)
Summary: Lineage switching can induce therapy resistance in cancer. Yet, how lineage fidelity is maintained and how it can be lost remain poorly understood. Here, we have used CRISPR-Cas9-based genetic screening to demonstrate that loss of SMARCB1, a
Externí odkaz:
https://doaj.org/article/629e571c05cc491594e2cb0fca3f5f9e
Autor:
Xusheng Wang, Haiyan Chen, Ruiyun Tian, Yiling Zhang, Marina S. Drutskaya, Chengmei Wang, Jianfeng Ge, Zhimeng Fan, Deqiang Kong, Xiaoxiao Wang, Ting Cai, Ying Zhou, Jingwen Wang, Jinmei Wang, Shan Wang, Zhihai Qin, Huanhuan Jia, Yue Wu, Jia Liu, Sergei A. Nedospasov, Edward E. Tredget, Mei Lin, Jianjun Liu, Yuyang Jiang, Yaojiong Wu
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Hair can be regenerated after skin wounding. Here the authors show that inflammatory macrophages produce TNF that activates Wnt signalling in hair follicle stem cells to drive this hair regeneration after wound repair in mice.
Externí odkaz:
https://doaj.org/article/c1280a37456c4ba7b643279d85e82d64
Publikováno v:
Cells, Vol 10, Iss 4, p 942 (2021)
MRCKα is a ubiquitously expressed serine/threonine kinase involved in cell contraction and F-actin turnover, which is highly amplified in human breast cancer and part of a gene expression signature for bad prognosis. Nothing is known about the in vi
Externí odkaz:
https://doaj.org/article/552a74e0f2cd405881e4dc8bc949b6f3
Publikováno v:
Cells, Vol 10, Iss 942, p 942 (2021)
Cells
Volume 10
Issue 4
Kwa, M Q, Brandao, R, Phung, T H, Ge, J, Scieri, G & Brakebusch, C 2021, ' MRCKα Is Dispensable for Breast Cancer Development in the MMTV-PyMT Model ', Cells, vol. 10, no. 4, 942 . https://doi.org/10.3390/cells10040942
Cells
Volume 10
Issue 4
Kwa, M Q, Brandao, R, Phung, T H, Ge, J, Scieri, G & Brakebusch, C 2021, ' MRCKα Is Dispensable for Breast Cancer Development in the MMTV-PyMT Model ', Cells, vol. 10, no. 4, 942 . https://doi.org/10.3390/cells10040942
MRCKα is a ubiquitously expressed serine/threonine kinase involved in cell contraction and F-actin turnover, which is highly amplified in human breast cancer and part of a gene expression signature for bad prognosis. Nothing is known about the in vi
Autor:
Tianchen Yu, Zhongguo Li, Wenfa Zhou, Xingzhi Wu, Jidong Jia, Ruipeng Niu, Jianfeng Ge, Junyi Yang, Yinglin Song
Publikováno v:
Optical Materials. 123:111923
Autor:
Klemens Rottner, Mei Qi Kwa, Cord Brakebusch, Laurent Burnier, Maria Adamopoulou, Jianfeng Ge, Matthias Schaks
Publikováno v:
The Journal of biological chemistry
Mesenchymal stem cells (MSC) are suggested to be important progenitors of myofibroblasts in fibrosis. To understand the role of Rho GTPase signaling in TGFβ-induced myofibroblast differentiation of MSC, we generated a novel MSC line and its descenda
Autor:
Edward E. Tredget, Shan X. Wang, Zhihai Qin, Deqiang Kong, Ting Cai, Haiyan Chen, Yaojiong Wu, Chengmei Wang, Yuyang Jiang, Jinmei Wang, Yue Wu, Jianjun Liu, Xiaoxiao Wang, Marina S. Drutskaya, Sergei A. Nedospasov, Jianfeng Ge, Huanhuan Jia, Xusheng Wang, Zhimeng Fan, Yiling Zhang, Mei Lin, Ying Zhou, Jia Liu, Jingwen Wang, Ruiyun Tian
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Skin stem cells can regenerate epidermal appendages; however, hair follicles (HF) lost as a result of injury are barely regenerated. Here we show that macrophages in wounds activate HF stem cells, leading to telogen–anagen transition (TAT) around t
Autor:
Shan X. Wang, Yaojiong Wu, Jianfeng Ge, Robert C Chunhua Zhao, Ruiyun Tian, Lin Yu, Ting Cai, Yuyang Jiang, Ling Guo
Publikováno v:
Stem Cells. 33:3315-3326
Mesenchymal stem cells (MSCs) are largely entrapped in the lungs after intravenous delivery. The underlying mechanisms have been poorly understood. Flow cytometry and Western blot analysis showed that the expression levels of many integrins such as
Publikováno v:
Stem Cells and Development. 23:978-989
The therapeutic effect of mesenchymal stem cells (MSCs) in tissue repair/regeneration is substantially dampened by the loss of primitive properties and poor engraftment to target organs. In this study, the multipotency and cell sizes of human MSCs, w