Zobrazeno 1 - 10
of 381
pro vyhledávání: '"Jianfang Chen"'
Autor:
Xin Chen, Kexin Wang, Jianfang Chen, Chao Wu, Jun Mao, Yuanpeng Song, Yijing Liu, Zhenhua Shao, Xuemei Pu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Allosteric drugs offer a new avenue for modern drug design. However, the identification of cryptic allosteric sites presents a formidable challenge. Following the allostery nature of residue-driven conformation transition, we propose a state
Externí odkaz:
https://doaj.org/article/585d508369294ffd998b10f17db2e8a5
Autor:
Tong Cao, Feng Zhou, Di Tian, Qicheng Meng, Xiao Ma, Bin Wang, Qianjiang Zhang, Jiliang Xuan, Jianfang Chen, Daji Huang
Publikováno v:
Frontiers in Marine Science, Vol 11 (2024)
The degradation of coastal seawater quality off the Changjiang Estuary and adjacent waters is typically associated with monsoon wind, ocean currents and inputs of terrestrial pollutants. In addition to these factors, the passage of typhoons can be al
Externí odkaz:
https://doaj.org/article/68a6c6684fac4ec9a652e62adc6b127c
Publikováno v:
PeerJ, Vol 12, p e17862 (2024)
Background Chemotactic cytokines play a crucial role in the development of acute myeloid leukemia (AML). Thus, investigating the mechanisms of chemotactic cytokine-related genes (CCRGs) in AML is of paramount importance. Methods Using the TCGA-AML, G
Externí odkaz:
https://doaj.org/article/c26b6e4b58ba448f9a78907a005a54d4
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionCD8+T cell tolerance plays an important role in tumor escape. Recent studies have shown that CD45+ erythroid progenitor cells (CD45+EPCs) generated through splenic extramedullary erythropoiesis suppress tumor immunity. However, the mechan
Externí odkaz:
https://doaj.org/article/5bd96557ac8a4eb283506e8b86ee38ec
Autor:
Pei Sun Loh, Jianjie He, Shida Feng, Yijin Wang, Zengxuan Chen, Chuanyi Guo, Shuangyan He, Xue-Gang Chen, Ai-Min Jin, Yuxia Sun, Jiawang Chen, Jianru Zhao, Zhongqiao Li, Jianfang Chen
Publikováno v:
Water, Vol 16, Iss 16, p 2225 (2024)
This study investigated the distribution of sedimentary phosphorus (P) species along an area of a rapid current at the southern coast of Zhoushan Island. The objective of this study was to improve the understanding of P cycling in a zone of rapid wat
Externí odkaz:
https://doaj.org/article/91d88b99f36c4508a3eb8624f4245fca
Autor:
Wenqi Ye, Xiao Ma, Chenggang Liu, Ruijie Ye, W. N. C. Priyadarshani, Ruchi Jayathilake, Ashoka Weerakoon, Udeshika Wimalasiri, P. A. K. N. Dissanayake, Gayan Pathirana, R. G. A. Iroshanie, Yuanli Zhu, Zhongqiao Li, Bin Wang, Lu Shou, Lihua Ran, Feng Zhou, Jianfang Chen, Ping Du
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
Marine environments wherein long-term microbial oxygen consumption exceeds oxygen replenishment can be associated with oxygen minimum zones (OMZ). The Bay of Bengal OMZ (BOB-OMZ) is one of the most intense OMZs globally. To assess the contribution of
Externí odkaz:
https://doaj.org/article/413dfea4f60a4af2a19a16bd587d4090
Autor:
Jingjing Zhang, Hongliang Li, Martin G. Wiesner, Lihua Ran, Xingju He, Guangxi Chi, Xinyang Wang, Jinping Yu, Jianfang Chen
Publikováno v:
Frontiers in Marine Science, Vol 10 (2023)
Accurately assessing the capacity of the modern ocean to photosynthetically fix and sequester atmospheric CO2, termed the biological carbon pump (BCP), is a key component in studies on the marine carbon cycle and the global climate system. Particulat
Externí odkaz:
https://doaj.org/article/4ab7bb0aa4df4eb29f5c4e8160cbdf33
Publikováno v:
Frontiers in Marine Science, Vol 10 (2023)
Externí odkaz:
https://doaj.org/article/564b5635d5c34945adb4f3b77fa12bd0
Autor:
Jianfang Chen, Shuang Wu, Yu Peng, Yang Zhao, Yan Dong, Fengwei Ran, Haofei Geng, Kang Zhang, Jianjun Li, Shuo Huang, Zhe Wang
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Background: Colorectal cancer (CRC) ranks the second malignancy with high incidence and mortality worldwide. Cancer stem cells (CSCs) function critically in cancer progression and metastasis via the interplay with immune cells in tumor microenvironme
Externí odkaz:
https://doaj.org/article/5c8e2a1517a6416e9db84e91bd4b4873
Autor:
Bassem Jalali, Marie-Alexandrine Sicre, Jian Ren, Vincent Klein, Zhongqiao Li, Liang Su, Youcheng Bai, Anatolii S Astakhov, Jianfang Chen
Publikováno v:
Environmental Research Communications, Vol 6, Iss 9, p 091013 (2024)
In this study, we reconstruct three-century of sea ice cover history in the Chukchi Sea from the downcore profile of total organic carbon (TOC) and biomarker proxies, namely the Ice Proxy with 25 carbon atoms (IP _25 ), the di- and tri-unsaturated hi
Externí odkaz:
https://doaj.org/article/f0591a0e53d6493c983e306df9217467