Zobrazeno 1 - 10
of 99
pro vyhledávání: '"Jiancun Zhang"'
Autor:
Tianxi Ye, Jinge Zhou, Chen Guo, Kaiyue Zhang, Yuping Wang, Yanhui Liu, Junhui Zhou, Yalin Xie, Entao Li, Rui Gong, Jiancun Zhang, Xia Chuai, Sandra Chiu
Publikováno v:
Cell Reports, Vol 43, Iss 6, Pp 114269- (2024)
Summary: The 2022 mpox outbreak led the World Health Organization (WHO) to declare it a public health emergency of international concern (PHEIC). There is a need to develop more effective and safer mpox virus (MPXV)-specific vaccines in response to t
Externí odkaz:
https://doaj.org/article/ff40d66c91494b0796b5f583f220ead0
Autor:
Muzammal Hussain, Yongzhi Lu, Muqddas Tariq, Hao Jiang, Yahai Shu, Shuang Luo, Qiang Zhu, Jiancun Zhang, Jinsong Liu
Publikováno v:
iScience, Vol 25, Iss 7, Pp 104591- (2022)
Summary: Skp1 overexpression promotes tumor growth, whereas reduced Skp1 activity is also linked with genomic instability and neoplastic transformation. This highlights the need to gain better understanding of Skp1 biology in cancer settings. To this
Externí odkaz:
https://doaj.org/article/548250b965894382b6037b62611e00d1
Publikováno v:
智能科学与技术学报, Vol 1, Pp 140-144 (2019)
Controlling the balance of a movable rod or a wine cup filled with water on a four axis air vehicle is a hard job.A system called four axis air vehicle-inverted pendulum balance control system is needed.With this special kind of balance control syste
Externí odkaz:
https://doaj.org/article/68322b1a19d448cb928b244048409ef4
Publikováno v:
Organic Letters. 23:7630-7634
Herein, we report a highly efficient organocatalytic asymmetric synthesis of axially chiral biaryl phosphonates with p-quinone phosphonates and 2-naphthols via CPA-catalyzed asymmetric arylations. A series of chiral biaryl monophosphonates were obtai
Publikováno v:
The Journal of Organic Chemistry. 85:10584-10592
A new type of spirocyclic bisoxindole-based C2-symmetric diols (SBIDOLs) was designed and synthesized. A series of racemic SBIDOL derivatives (6a-6g) were readily synthesized from commercially available 2-halo-5-methoxyanilines 1 (X = Cl or Br) throu
Autor:
Guoqiang Yao, Jianchen Yu, Cai Lin, Yujia Zhu, Anna Duan, Mengfeng Li, Jie Yuan, Jiancun Zhang
Publikováno v:
European journal of medicinal chemistry. 234
Zika virus (ZIKV) is a mosquito-borne flavivirus and outbreaks of ZIKV have been reported in Africa, Americas and other parts of the world lately. The ZIKV epidemic has received extensive attention due to its ability to cause serious medical conseque
Publikováno v:
Organic letters. 23(19)
Herein, we report a highly efficient organocatalytic asymmetric synthesis of axially chiral biaryl phosphonates with
Autor:
Yuejia Huang, Lin Lin, Xing Liu, Sheng Ye, Phil Y. Yao, Wenwen Wang, Fengrui Yang, Xinjiao Gao, Junying Li, Yin Zhang, Jiancun Zhang, Zhihong Yang, Xu Liu, Zhenye Yang, Jianye Zang, Maikun Teng, Zhiyong Wang, Ke Ruan, Xia Ding, Lin Li, Don W. Cleveland, Rongguang Zhang, Xuebiao Yao
Publikováno v:
Cell research, vol 29, iss 7
Cell Res
Cell Res
Error-free mitosis depends on accurate chromosome attachment to spindle microtubules, powered congression of those chromosomes, their segregation in anaphase, and assembly of a spindle midzone at mitotic exit. The centromere-associated kinesin motor
Publikováno v:
Life Sciences. 227:175-186
The tumor microenvironment comprises stromal and tumor cells which interact with each other through complex cross-talks that are mediated by a variety of growth factors, cytokines, and chemokines. The chemokine ligand 13 (CXCL13) and its chemokine re
Publikováno v:
Organic Process Research & Development. 23:1204-1212
An efficient and scalable synthesis of eliglustat (1) is herein reported. This novel route features a three-step telescoped process to afford the α-dibenzylamino β-ketoester 6 in 85% overall yield ...